How do ALS-associated mutations in superoxide dismutase 1 promote aggregation of the protein? BF Shaw, JS Valentine Trends in biochemical sciences 32 (2), 78-85, 2007 | 301 | 2007 |
Destabilization of apoprotein is insufficient to explain Cu, Zn-superoxide dismutase-linked ALS pathogenesis JA Rodriguez, BF Shaw, A Durazo, SH Sohn, PA Doucette, AM Nersissian, ... Proceedings of the National Academy of Sciences 102 (30), 10516-10521, 2005 | 209 | 2005 |
Abnormal SDS‐PAGE migration of cytosolic proteins can identify domains and mechanisms that control surfactant binding Y Shi, RA Mowery, J Ashley, M Hentz, AJ Ramirez, B Bilgicer, ... Protein Science 21 (8), 1197-1209, 2012 | 181 | 2012 |
Loss of metal ions, disulfide reduction and mutations related to familial ALS promote formation of amyloid-like aggregates from superoxide dismutase ZA Oztug Durer, JA Cohlberg, P Dinh, S Padua, K Ehrenclou, S Downes, ... PloS one 4 (3), e5004, 2009 | 150 | 2009 |
PAI-1 promotes extracellular matrix deposition in the airways of a murine asthma model CK Oh, B Ariue, RF Alban, B Shaw, SH Cho Biochemical and biophysical research communications 294 (5), 1155-1160, 2002 | 148 | 2002 |
Binding of a single zinc ion to one subunit of copper− zinc superoxide dismutase apoprotein substantially influences the structure and stability of the entire homodimeric protein SZ Potter, H Zhu, BF Shaw, JA Rodriguez, PA Doucette, SH Sohn, ... Journal of the American Chemical Society 129 (15), 4575-4583, 2007 | 137 | 2007 |
Detergent-insoluble aggregates associated with amyotrophic lateral sclerosis in transgenic mice contain primarily full-length, unmodified superoxide dismutase-1 BF Shaw, HL Lelie, A Durazo, AM Nersissian, G Xu, PK Chan, EB Gralla, ... Journal of Biological Chemistry 283 (13), 8340-8350, 2008 | 103 | 2008 |
Insights into the role of the unusual disulfide bond in copper-zinc superoxide dismutase K Sea, SH Sohn, A Durazo, Y Sheng, BF Shaw, X Cao, AB Taylor, ... Journal of Biological Chemistry 290 (4), 2405-2418, 2015 | 92 | 2015 |
Lysine acetylation can generate highly charged enzymes with increased resistance toward irreversible inactivation BF Shaw, GF Schneider, B Bilgiçer, GK Kaufman, JM Neveu, WS Lane, ... Protein science 17 (8), 1446-1455, 2008 | 91 | 2008 |
Local unfolding in a destabilized, pathogenic variant of superoxide dismutase 1 observed with H/D exchange and mass spectrometry BF Shaw, A Durazo, AM Nersissian, JP Whitelegge, KF Faull, ... Journal of Biological Chemistry 281 (26), 18167-18176, 2006 | 83 | 2006 |
Deamidation of asparagine to aspartate destabilizes Cu, Zn superoxide dismutase, accelerates fibrillization, and mirrors ALS-linked mutations Y Shi, NR Rhodes, A Abdolvahabi, T Kohn, NP Cook, AA Marti, BF Shaw Journal of the American Chemical Society 135 (42), 15897-15908, 2013 | 66 | 2013 |
Pathway for unfolding of ubiquitin in sodium dodecyl sulfate, studied by capillary electrophoresis GF Schneider, BF Shaw, A Lee, E Carillho, GM Whitesides Journal of the American Chemical Society 130 (51), 17384-17393, 2008 | 59 | 2008 |
Arresting amyloid with coulomb’s law: acetylation of ALS-linked SOD1 by aspirin impedes aggregation A Abdolvahabi, Y Shi, NR Rhodes, NP Cook, AA Martí, BF Shaw Biophysical journal 108 (5), 1199-1212, 2015 | 55 | 2015 |
Complexes of native ubiquitin and dodecyl sulfate illustrate the nature of hydrophobic and electrostatic interactions in the binding of proteins and surfactants BF Shaw, GF Schneider, H Arthanari, M Narovlyansky, D Moustakas, ... Journal of the American Chemical Society 133 (44), 17681-17695, 2011 | 55 | 2011 |
A non-chromatographic method for the purification of a bivalently active monoclonal IgG antibody from biological fluids B Bilgiçer, SW Thomas III, BF Shaw, GK Kaufman, VM Krishnamurthy, ... Journal of the American Chemical Society 131 (26), 9361-9367, 2009 | 52 | 2009 |
Metal-free superoxide dismutase-1 and three different amyotrophic lateral sclerosis variants share a similar partially unfolded β-barrel at physiological temperature A Durazo, BF Shaw, M Chattopadhyay, KF Faull, AM Nersissian, ... Journal of Biological Chemistry 284 (49), 34382-34389, 2009 | 49 | 2009 |
Stochastic formation of fibrillar and amorphous superoxide dismutase oligomers linked to amyotrophic lateral sclerosis A Abdolvahabi, Y Shi, A Chuprin, S Rasouli, BF Shaw ACS chemical neuroscience 7 (6), 799-810, 2016 | 47 | 2016 |
Selective photocrosslinking of functional ligands to antibodies via the conserved nucleotide binding site NJ Alves, MM Champion, JF Stefanick, MW Handlogten, DT Moustakas, ... Biomaterials 34 (22), 5700-5710, 2013 | 46 | 2013 |
Neutralizing positive charges at the surface of a protein lowers its rate of amide hydrogen exchange without altering its structure or increasing its thermostability BF Shaw, H Arthanari, M Narovlyansky, A Durazo, DP Frueh, MP Pollastri, ... Journal of the American Chemical Society 132 (49), 17411-17425, 2010 | 41 | 2010 |
Autonomous early detection of eye disease in childhood photographs MC Munson, DL Plewman, KM Baumer, R Henning, CT Zahler, ... Science advances 5 (10), eaax6363, 2019 | 37 | 2019 |