Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase DP Hanger, K Hughes, JR Woodgett, JP Brion, BH Anderton Neuroscience letters 147 (1), 58-62, 1992 | 948 | 1992 |
MISE EN ÉVIDENCE IMMUNOLOGIQUE DE LA PROTEINE TAU AU NIVEAU DES LESIONS DE DEGENERESCENCE NEUROFIBRILLAIRE DE LA MALADIE D‘ALZHEIMER JP BRION, H Passareiro, J NUNEZ, J Jacqueline FLAMENT-DURAND Archives de Biologie 95, 229-235, 1985 | 465* | 1985 |
Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits K Schindowski, A Bretteville, K Leroy, S Bégard, JP Brion, M Hamdane, ... The American journal of pathology 169 (2), 599-616, 2006 | 447 | 2006 |
Increased level of active GSK‐3β in Alzheimer’s disease and accumulation in argyrophilic grains and in neurones at different stages of neurofibrillary degeneration K Leroy, Z Yilmaz, JP Brion Neuropathology and applied neurobiology 33 (1), 43-55, 2007 | 443 | 2007 |
What is the evidence that tau pathology spreads through prion-like propagation? A Mudher, M Colin, S Dujardin, M Medina, I Dewachter, SM Alavi Naini, ... Acta neuropathologica communications 5, 1-20, 2017 | 346 | 2017 |
Neurofibrillary tangles of Alzheimer's disease: an immunohistochemical study. JP Brion, AM Couck, E Passareiro, J Flament-Durand Journal of submicroscopic cytology 17 (1), 89-96, 1985 | 329 | 1985 |
PART is part of Alzheimer disease C Duyckaerts, H Braak, JP Brion, L Buée, K Del Tredici, M Goedert, ... Acta neuropathologica 129, 749-756, 2015 | 304 | 2015 |
Developmental expression and localization of glycogen synthase kinase-3β in rat brain K Leroy, JP Brion Journal of chemical neuroanatomy 16 (4), 279-293, 1999 | 290 | 1999 |
Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation R Dayanandan, M Van Slegtenhorst, TGA Mack, L Ko, SH Yen, K Leroy, ... FEBS letters 446 (2-3), 228-232, 1999 | 262 | 1999 |
Neurofibrillary tangles and Alzheimer’s disease JP Brion European neurology 40 (3), 130-140, 1998 | 259 | 1998 |
Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt–PCP–JNK pathway R Killick, EM Ribe, R Al-Shawi, B Malik, C Hooper, C Fernandes, ... Molecular psychiatry 19 (1), 88-98, 2014 | 258 | 2014 |
Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's disease JP Brion, G Tremp, JN Octave The American journal of pathology 154 (1), 255-270, 1999 | 255 | 1999 |
Developmental Changes in τ Phosphorylation: Fetal τ Is Transiently Phosphorylated in a Manner Similar to Paired Helical Filament‐τ Characteristic of Alzheimer's Disease JP Brion, C Smith, AM Couck, JM Gallo, BH Anderton Journal of neurochemistry 61 (6), 2071-2080, 1993 | 243 | 1993 |
Hallmarks of Alzheimer’s disease in stem-cell-derived human neurons transplanted into mouse brain I Espuny-Camacho, AM Arranz, M Fiers, A Snellinx, K Ando, S Munck, ... Neuron 93 (5), 1066-1081. e8, 2017 | 233 | 2017 |
Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase P Derkinderen, TME Scales, DP Hanger, KY Leung, HL Byers, MA Ward, ... Journal of Neuroscience 25 (28), 6584-6593, 2005 | 232 | 2005 |
The active form of glycogen synthase kinase-3β is associated with granulovacuolar degeneration in neurons in Alzheimer's disease K Leroy, A Boutajangout, M Authelet, JR Woodgett, BH Anderton, JP Brion Acta neuropathologica 103, 91-99, 2002 | 230 | 2002 |
Reduction of acetylated α-tubulin immunoreactivity in neurofibrillary tangle-bearing neurons in Alzheimer's disease B Hempen, JP Brion Journal of Neuropathology & Experimental Neurology 55 (9), 964-972, 1996 | 212 | 1996 |
Abnormalities of Wnt signalling in schizophrenia–evidence for neurodevelopmental abnormality D Cotter, R Kerwin, S Al-Sarraji, JP Brion, A Chadwich, S Lovestone, ... Neuroreport 9 (7), 1379-1383, 1998 | 211 | 1998 |
Lithium reduces tau phosphorylation: effects in living cells and in neurons at therapeutic concentrations S Lovestone, DR Davis, MT Webster, S Kaech, JP Brion, A Matus, ... Biological psychiatry 45 (8), 995-1003, 1999 | 200 | 1999 |
Tau in Alzheimer neurofibrillary tangles. N- and C-terminal regions are differentially associated with paired helical filaments and the location of a putative abnormal … JP Brion, DP Hanger, MT Bruce, AM Couck, J Flament-Durand, ... Biochemical journal 273 (1), 127-133, 1991 | 184 | 1991 |