The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals N Zhang, H Bai, KK David, J Dong, Y Zheng, J Cai, M Giovannini, P Liu, ... Developmental cell 19 (1), 27-38, 2010 | 849 | 2010 |
Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon KM Haigis, KR Kendall, Y Wang, A Cheung, MC Haigis, JN Glickman, ... Nature genetics 40 (5), 600-608, 2008 | 707 | 2008 |
A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system IG Boneca, O Dussurget, D Cabanes, MA Nahori, S Sousa, M Lecuit, ... Proceedings of the National Academy of Sciences 104 (3), 997-1002, 2007 | 426 | 2007 |
Liver-targeted disruption of Apc in mice activates β-catenin signaling and leads to hepatocellular carcinomas S Colnot, T Decaens, M Niwa-Kawakita, C Godard, G Hamard, A Kahn, ... Proceedings of the National Academy of Sciences 101 (49), 17216-17221, 2004 | 404 | 2004 |
Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2 M Giovannini, E Robanus-Maandag, M van der Valk, M Niwa-Kawakita, ... Genes & development 14 (13), 1617-1630, 2000 | 404 | 2000 |
NF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions D Lallemand, M Curto, I Saotome, M Giovannini, AI McClatchey Genes & development 17 (9), 1090-1100, 2003 | 382 | 2003 |
Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4DCAF1 in the nucleus W Li, L You, J Cooper, G Schiavon, A Pepe-Caprio, L Zhou, R Ishii, ... Cell 140 (4), 477-490, 2010 | 375 | 2010 |
Membrane organization and tumorigenesis—the NF2 tumor suppressor, Merlin AI McClatchey, M Giovannini Genes & development 19 (19), 2265-2277, 2005 | 369 | 2005 |
Gene–environment interaction modulated by allelic heterogeneity in inflammatory diseases M Chamaillard, D Philpott, SE Girardin, H Zouali, S Lesage, F Chareyre, ... Proceedings of the National Academy of Sciences 100 (6), 3455-3460, 2003 | 360 | 2003 |
MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors WJ Jessen, SJ Miller, E Jousma, J Wu, TA Rizvi, ME Brundage, D Eaves, ... The Journal of clinical investigation 123 (1), 340-347, 2013 | 357 | 2013 |
Cre-mediated somatic site-specific recombination in mice K Akagi, M Vooijs, M Van der Valk, M Giovannini, A Berns, V Sandig, ... Nucleic acids research 25 (9), 1766-1773, 1997 | 351 | 1997 |
Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver S Benhamouche, M Curto, I Saotome, AB Gladden, CH Liu, M Giovannini, ... Genes & development 24 (16), 1718-1730, 2010 | 325 | 2010 |
Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of Ras and Rac H Morrison, T Sperka, J Manent, M Giovannini, H Ponta, P Herrlich Cancer research 67 (2), 520-527, 2007 | 264 | 2007 |
Nf2 gene inactivation in arachnoidal cells is rate-limiting for meningioma development in the mouse M Kalamarides, M Niwa-Kawakita, H Leblois, V Abramowski, ... Genes & development 16 (9), 1060-1065, 2002 | 252 | 2002 |
Colorectal cancers in a new mouse model of familial adenomatous polyposis: influence of genetic and environmental modifiers S Colnot, M Niwa-Kawakita, G Hamard, C Godard, S Le Plenier, ... Laboratory investigation 84 (12), 1619-1630, 2004 | 227 | 2004 |
Update from the 2011 International Schwannomatosis Workshop: From genetics to diagnostic criteria SR Plotkin, JO Blakeley, DG Evans, CO Hanemann, TJM Hulsebos, ... American journal of medical genetics Part A 161 (3), 405-416, 2013 | 197 | 2013 |
Card15 gene overexpression in mononuclear and epithelial cells of the inflamed Crohn’s disease colon D Berrebi, R Maudinas, JP Hugot, M Chamaillard, F Chareyre, ... Gut 52 (6), 840-846, 2003 | 196 | 2003 |
Murine Nod1 but not its human orthologue mediates innate immune detection of tracheal cytotoxin JG Magalhaes, DJ Philpott, MA Nahori, M Jéhanno, J Fritz, L Bourhis Le, ... EMBO reports 6 (12), 1201-1207, 2005 | 192 | 2005 |
EWS-erg and EWS-Fli1 fusion transcripts in Ewing's sarcoma and primitive neuroectodermal tumors with variant translocations. M Giovannini, JA Biegel, M Serra, JY Wang, YH Wei, L Nycum, ... The Journal of clinical investigation 94 (2), 489-496, 1994 | 188 | 1994 |
CARD15/NOD2 is required for Peyer's patches homeostasis in mice F Barreau, U Meinzer, F Chareyre, D Berrebi, M Niwa-Kawakita, ... PloS one 2 (6), e523, 2007 | 184 | 2007 |