| Bacillus thuringiensisCrylA (a) insecticidal toxin: crystal structure and channel formation P Grochulski, L Masson, S Borisova, M Pusztai-Carey, JL Schwartz, ... Journal of molecular biology 254 (3), 447-464, 1995 | 792 | 1995 |
| Insights into interfacial activation from an open structure of Candida rugosa lipase P Grochulski, Y Li, JD Schrag, F Bouthillier, P Smith, D Harrison, B Rubin, ... Journal of Biological Chemistry 268 (17), 12843-12847, 1993 | 724 | 1993 |
| Two conformational states of Candida rugosa lipase P Grochulski, Y Li, JD Schrag, M Cygler Protein Science 3 (1), 82-91, 1994 | 488 | 1994 |
| A structural basis for the chiral preferences of lipases M Cygler, P Grochulski, RJ Kazlauskas, JD Schrag, F Bouthillier, B Rubin, ... Journal of the American Chemical Society 116 (8), 3180-3186, 1994 | 467 | 1994 |
| Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment. R Coulombe, P Grochulski, J Sivaraman, R Menard, JS Mort, M Cygler The EMBO journal 15 (20), 5492-5503, 1996 | 458 | 1996 |
| Analogs of reaction intermediates identify a unique substrate binding site in Candida rugosa lipase P Grochulski, F Bouthillier, RJ Kazlauskas, AN Serreqi, JD Schrag, ... Biochemistry 33 (12), 3494-3500, 1994 | 330 | 1994 |
| Three-dimensional structure of holo 3 alpha, 20 beta-hydroxysteroid dehydrogenase: a member of a short-chain dehydrogenase family. D Ghosh, CM Weeks, P Grochulski, WL Duax, M Erman, RL Rimsay, ... Proceedings of the National Academy of Sciences 88 (22), 10064-10068, 1991 | 315 | 1991 |
| Structure of a calpain Ca2+-binding domain reveals a novel EF-hand and Ca2+-induced conformational changes H Blanchard, P Grochulski, Y Li, JSC Arthur, PL Davies, JS Elce, M Cygler Nature Structural Biology 4 (7), 532-538, 1997 | 279 | 1997 |
| Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion M Cygler, J Sivaraman, P Grochulski, R Coulombe, AC Storer, JS Mort Structure 4 (4), 405-416, 1996 | 240 | 1996 |
| Structural insights into mechanisms of catalysis and inhibition in Norwalk virus polymerase DF Zamyatkin, F Parra, JMM Alonso, DA Harki, BR Peterson, P Grochulski, ... Journal of Biological Chemistry 283 (12), 7705-7712, 2008 | 164 | 2008 |
| Restriction of intramolecular movements within the Cry1Aa toxin molecule of Bacillus thuringiensis through disulfide bond engineering JL Schwartz, M Juteau, P Grochulski, M Cygler, G Préfontaine, ... FEBS letters 410 (2-3), 397-402, 1997 | 161 | 1997 |
| Molecular structure and mechanisms of action of cyclic and linear ion transport antibiotics WL Duax, JF Griffin, DA Langs, GD Smith, P Grochulski, V Pletnev, ... Peptide Science 40 (1), 141-155, 1996 | 99 | 1996 |
| Beamline 08ID-1, the prime beamline of the Canadian Macromolecular Crystallography Facility P Grochulski, MN Fodje, J Gorin, SL Labiuk, R Berg Journal of synchrotron radiation 18 (4), 681-684, 2011 | 93 | 2011 |
| Enantioselectivity of Candida Rugosa Lipase Toward Carboxylic Acids: A Predictive Rule from Substrate Mapping and X-Ray Crystallography SN Ahmed, RJ Kazlauskas, AH Morinville, P Grochulski, JD Schrag, ... Biocatalysis 9 (1-4), 209-225, 1994 | 92 | 1994 |
| Metalloprotein active site structure determination: synergy between X-ray absorption spectroscopy and X-ray crystallography JJH Cotelesage, MJ Pushie, P Grochulski, IJ Pickering, GN George Journal of inorganic biochemistry 115, 127-137, 2012 | 91 | 2012 |
| Covalent intermediate trapped in 2-keto-3-deoxy-6-phosphogluconate (KDPG) aldolase structure at 1.95-Å resolution J Allard, P Grochulski, J Sygusch Proceedings of the National Academy of Sciences 98 (7), 3679-3684, 2001 | 76 | 2001 |
| Binding of 2′-amino-2′-deoxycytidine-5′-triphosphate to norovirus polymerase induces rearrangement of the active site DF Zamyatkin, F Parra, Á Machín, P Grochulski, KKS Ng Journal of molecular biology 390 (1), 10-16, 2009 | 71 | 2009 |
| 08B1-1: an automated beamline for macromolecular crystallography experiments at the Canadian Light Source M Fodje, P Grochulski, K Janzen, S Labiuk, J Gorin, R Berg Journal of synchrotron radiation 21 (3), 633-637, 2014 | 67 | 2014 |
| Roles of individual EF-hands in the activation of m-calpain by calcium P Dutt, JCS Arthur, P Grochulski, M Cygler, JS Elce Biochemical journal 348 (1), 37-43, 2000 | 55 | 2000 |
| Calcium stiffens archaeal Rad51 recombinase from Methanococcus voltae for homologous recombination X Qian, Y He, X Ma, MN Fodje, P Grochulski, Y Luo Journal of Biological Chemistry 281 (51), 39380-39387, 2006 | 36 | 2006 |
