Understanding microRNA-mediated gene regulatory networks through mathematical modelling X Lai, O Wolkenhauer, J Vera Nucleic Acids Research 44 (13), 6019-6035, 2016 | 176 | 2016 |
Systems biology-based investigation of cooperating microRNAs as monotherapy or adjuvant therapy in cancer X Lai, M Eberhardt, U Schmitz, J Vera Nucleic acids research 47 (15), 7753-7766, 2019 | 148 | 2019 |
Artificial intelligence in cancer target identification and drug discovery Y You, X Lai, Y Pan, H Zheng, J Vera, S Liu, S Deng, L Zhang Signal Transduction and Targeted Therapy 7 (156), 2022 | 131 | 2022 |
Computational analysis of target hub gene repression regulated by multiple and cooperative miRNAs X Lai, U Schmitz, SK Gupta, A Bhattacharya, M Kunz, O Wolkenhauer, ... Nucleic Acids Research 40 (18), 8818-8834, 2012 | 97 | 2012 |
Cooperative gene regulation by microRNA pairs and their identification using a computational workflow U Schmitz, X Lai, F Winter, O Wolkenhauer, J Vera, SK Gupta Nucleic acids research 42 (12), 7539-7552, 2014 | 95 | 2014 |
MiR-205-5p and miR-342-3p cooperate in the repression of the E2F1 transcription factor in the context of anticancer chemotherapy resistance X Lai, SK Gupta, U Schmitz, S Marquardt, S Knoll, A Spitschak, ... Theranostics 8 (4), 1106-1120, 2018 | 68 | 2018 |
Kinetic Modeling-Based Detection of Genetic Signatures that Provide Chemoresistance via the E2F1-p73/DNp73-miR-205 Network J Vera, U Schmitz, X Lai, D Engelmann, FM Khan, O Wolkenhauer, ... Cancer Research, 2013 | 65 | 2013 |
MicroRNA-Regulated Networks: The Perfect Storm for Classical Molecular Biology, the Ideal Scenario for Systems Biology. J Vera, X Lai, U Schmitz, O Wolkenhauer Advances in experimental medicine and biology 774, 55-76, 2012 | 63 | 2012 |
Exosomal lncRNAs and cancer: connecting the missing links H Naderi-Meshkin, X Lai, R Amirkhah, J Vera, JEJ Rasko, U Schmitz Bioinformatics 35 (2), 352-360, 2019 | 59 | 2019 |
Serum levels of miR-320 family members are associated with clinical parameters and diagnosis in prostate cancer patients V Lieb, K Weigelt, L Scheinost, K Fischer, T Greither, M Marcou, G Theil, ... Oncotarget, 2017 | 55 | 2017 |
A gene regulatory architecture that controls region‐independent dynamics of oligodendrocyte differentiation M Cantone, M Küspert, S Reiprich, X Lai, M Eberhardt, P Göttle, F Beyer, ... Glia, 2019 | 43 | 2019 |
Asthma phenotyping, therapy, and prevention: what can we learn from systems biology? A Sittka, J Vera, X Lai, BT Schmeck Pediatric research, 2013 | 42 | 2013 |
A Systems’ Biology Approach to Study MicroRNA‐Mediated Gene Regulatory Networks X Lai, A Bhattacharya, U Schmitz, M Kunz, J Vera, O Wolkenhauer BioMed research international 2013 (1), 703849, 2013 | 40 | 2013 |
Modeling miRNA regulation in cancer signaling systems: miR-34a regulation of the p53/Sirt1 signaling module X Lai, O Wolkenhauer, J Vera Computational Modeling of Signaling Networks, 87-108, 2012 | 39 | 2012 |
MicroRNA Clusters X Lai, J Vera Encyclopedia of Systems Biology, 1310-1314, 2013 | 28 | 2013 |
Innate extracellular vesicles from melanoma patients suppress β-catenin in tumor cells by miRNA-34a JH Lee, J Dindorf, M Eberhardt, X Lai, C Ostalecki, N Koliha, S Gross, ... Life science alliance 2 (2), 2019 | 25 | 2019 |
Multiplicity of mathematical modeling strategies to search for molecular and cellular insights into bacteria lung infection M Cantone, G Santos, P Wentker, X Lai, J Vera Frontiers in physiology 8, 645, 2017 | 24 | 2017 |
RNA sequencing of collecting duct renal cell carcinoma suggests an interaction between miRNA and target genes and a predominance of deregulated solute carrier genes S Wach, H Taubert, K Weigelt, N Hase, M Köhn, D Misiak, S Hüttelmaier, ... Cancers 12 (1), 64, 2020 | 22 | 2020 |
THP-1-derived macrophages render lung epithelial cells hypo-responsive to Legionella pneumophila–a systems biology study C Schulz, X Lai, W Bertrams, AL Jung, A Sittka-Stark, CE Herkt, H Janga, ... Scientific reports 7 (1), 1-15, 2017 | 22 | 2017 |
Third-kind encounters in biomedicine: immunology meets mathematics and informatics to become quantitative and predictive M Eberhardt, X Lai, N Tomar, S Gupta, B Schmeck, A Steinkasserer, ... Systems Medicine, 135-179, 2016 | 22 | 2016 |