Directed evolution of cytochrome c for carbon–silicon bond formation: Bringing silicon to life SBJ Kan, RD Lewis, K Chen, FH Arnold Science 354 (6315), 1048-1051, 2016 | 586 | 2016 |
Machine learning-assisted directed protein evolution with combinatorial libraries Z Wu, SBJ Kan, RD Lewis, BJ Wittmann, FH Arnold Proceedings of the National Academy of Sciences 116 (18), 8852-8858, 2019 | 489 | 2019 |
Genetically programmed chiral organoborane synthesis SBJ Kan, X Huang, Y Gumulya, K Chen, FH Arnold Nature 552 (7683), 132-136, 2017 | 282 | 2017 |
Enzymatic construction of highly strained carbocycles K Chen, X Huang, SBJ Kan, RK Zhang, FH Arnold Science 360 (6384), 71-75, 2018 | 221 | 2018 |
The impact of the Mukaiyama aldol reaction in total synthesis SBJ Kan, KKH Ng, I Paterson Angewandte Chemie International Edition 52 (35), 9097-9108, 2013 | 177 | 2013 |
Diverse engineered heme proteins enable stereodivergent cyclopropanation of unactivated alkenes AM Knight, SBJ Kan, RD Lewis, OF Brandenberg, K Chen, FH Arnold ACS Central Science 4 (3), 372-377, 2018 | 131 | 2018 |
Catalytic iron-carbene intermediate revealed in a cytochrome c carbene transferase RD Lewis, M Garcia-Borràs, MJ Chalkley, AR Buller, KN Houk, SBJ Kan, ... Proceedings of the National Academy of Sciences 115 (28), 7308-7313, 2018 | 112 | 2018 |
A Biocatalytic Platform for Synthesis of Chiral α-Trifluoromethylated Organoborons X Huang, M Garcia-Borràs, K Miao, SBJ Kan, A Zutshi, KN Houk, ... ACS central science 5 (2), 270-276, 2019 | 92 | 2019 |
Highly stereoselective biocatalytic synthesis of key cyclopropane intermediate to ticagrelor KE Hernandez, H Renata, RD Lewis, SBJ Kan, C Zhang, J Forte, ... ACS catalysis 6 (11), 7810-7813, 2016 | 86 | 2016 |
A cascade palladium-mediated cross-coupling/electrocyclization approach to the construction of fused bi-and tricyclic rings SBJ Kan, EA Anderson Organic letters 10 (11), 2323-2326, 2008 | 54 | 2008 |
Diversity-oriented enzymatic synthesis of cyclopropane building blocks BJ Wittmann, AM Knight, JL Hofstra, SE Reisman, SB Jennifer Kan, ... ACS catalysis 10 (13), 7112-7116, 2020 | 51 | 2020 |
Catalyst‐Controlled, Enantioselective and Diastereodivergent Conjugate Addition of Aldehydes to Electron‐Deficient Olefins SBJ Kan, H Maruyama, M Akakura, T Kano, K Maruoka Angewandte Chemie, 2017 | 45 | 2017 |
Phase‐Transfer‐Catalyzed Asymmetric Synthesis of Axially Chiral Anilides K Liu, X Wu, SBJ Kan, S Shirakawa, K Maruoka Chemistry–An Asian Journal 8 (12), 3214-3221, 2013 | 42 | 2013 |
Synthesis of the C1− C13 tetraenoate subunit of the chivosazoles I Paterson, SBJ Kan, LJ Gibson Organic Letters 12 (16), 3724-3727, 2010 | 42 | 2010 |
Origin and Control of Chemoselectivity in Cytochrome c Catalyzed Carbene Transfer into Si–H and N–H bonds M Garcia-Borràs, SBJ Kan, RD Lewis, A Tang, G Jimenez-Osés, ... Journal of the American Chemical Society 143 (18), 7114-7123, 2021 | 37 | 2021 |
Die Bedeutung der Mukaiyama‐Aldolreaktion für die Totalsynthese SBJ Kan, KKH Ng, I Paterson Angewandte Chemie 125 (35), 9267-9279, 2013 | 37 | 2013 |
A palladium-mediated cascade cyclisation approach to the CDE cores of rubriflordilactone A and lancifodilactone G SBJ Kan Chemical Communications, 5818-5820, 2008 | 36 | 2008 |
A continuing career in biocatalysis: Frances H. Arnold R Fasan, SB Jennifer Kan, H Zhao ACS catalysis 9 (11), 9775-9788, 2019 | 34 | 2019 |
Engineered cytochrome c-catalyzed lactone-carbene B–H insertion K Chen, X Huang, SQ Zhang, AZ Zhou, SBJ Kan, X Hong, FH Arnold Synlett 30 (04), 378-382, 2019 | 34 | 2019 |
An Expedient Total Synthesis of Chivosazole F: an Actin‐Binding Antimitotic Macrolide from the Myxobacterium Sorangium Cellulosum S Williams, J Jin, SBJ Kan, M Li, LJ Gibson, I Paterson Angewandte Chemie International Edition 56 (2), 645-649, 2017 | 31 | 2017 |