Proteostasis impairment in protein-misfolding and-aggregation diseases MS Hipp, SH Park, FU Hartl Trends in cell biology 24 (9), 506-514, 2014 | 761 | 2014 |
PolyQ proteins interfere with nuclear degradation of cytosolic proteins by sequestering the Sis1p chaperone SH Park, Y Kukushkin, R Gupta, T Chen, A Konagai, MS Hipp, ... Cell 154 (1), 134-145, 2013 | 420 | 2013 |
Failure of RQC machinery causes protein aggregation and proteotoxic stress YJ Choe, SH Park, T Hassemer, R Körner, L Vincenz-Donnelly, ... Nature 531 (7593), 191-195, 2016 | 248 | 2016 |
Use of modular substrates demonstrates mechanistic diversity and reveals differences in chaperone requirement of ERAD C Taxis, R Hitt, SH Park, PM Deak, Z Kostova, DH Wolf Journal of Biological Chemistry 278 (38), 35903-35913, 2003 | 244 | 2003 |
The cytoplasmic Hsp70 chaperone machinery subjects misfolded and endoplasmic reticulum import-incompetent proteins to degradation via the ubiquitin–proteasome system SH Park, N Bolender, F Eisele, Z Kostova, J Takeuchi, P Coffino, DH Wolf Molecular biology of the cell 18 (1), 153-165, 2007 | 210 | 2007 |
Cytosolic protein Vms1 links ribosome quality control to mitochondrial and cellular homeostasis T Izawa, SH Park, L Zhao, FU Hartl, W Neupert Cell 171 (4), 890-903. e18, 2017 | 167 | 2017 |
Stress-dependent condensate formation regulated by the ubiquitin-related modifier Urm1 LV Cairo, X Hong, MBD Müller, P Yuste-Checa, C Jagadeesan, A Bracher, ... Cell 187 (17), 4656-4673. e28, 2024 | 4 | 2024 |
Molecular chaperones in protein quality control: from recognition to degradation SH Park | 2 | 2007 |
489 Day of the dead: pseudokinases and pseudophosphatases in physiology and disease MS Hipp, SH Park, FU Hartl, LJ Neukomm, MR Freeman, M Sotomayor, ... | | |
The cytoplasmic Hsp70 chaperone machinery subjects misfolded and ER import incompetent proteins to degradation via the ubiquitin-proteasome system. SH Park, N Bolender, F Eisele, Z Kostova, J Takeuchi, P Coffino, DH Wolf | | |