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Marc Kschonsak
Marc Kschonsak
Sr. Scientist Structural Biology, Genentech/Roche
在 gene.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Structural basis for a safety-belt mechanism that anchors condensin to chromosomes
M Kschonsak, F Merkel, S Bisht, J Metz, V Rybin, M Hassler, CH Haering
Cell 171 (3), 588-600. e24, 2017
1582017
Shaping mitotic chromosomes: From classical concepts to molecular mechanisms
M Kschonsak, CH Haering
BioEssays 37 (7), 755-766, 2015
1022015
Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism
BG Lee, F Merkel, M Allegretti, M Hassler, C Cawood, L Lecomte, ...
Nature structural & molecular biology 27 (8), 743-751, 2020
1002020
Real‐time detection of condensin‐driven DNA compaction reveals a multistep binding mechanism
JM Eeftens, S Bisht, J Kerssemakers, M Kschonsak, CH Haering, ...
The EMBO journal 36 (23), 3448-3457, 2017
912017
Condensin Smc2-Smc4 dimers are flexible and dynamic
JM Eeftens, AJ Katan, M Kschonsak, M Hassler, L de Wilde, EM Dief, ...
Cell reports 14 (8), 1813-1818, 2016
912016
Mapping degradation signals and pathways in a eukaryotic N-terminome
I Kats, A Khmelinskii, M Kschonsak, F Huber, RA Knieß, A Bartosik, ...
Molecular cell 70 (3), 488-501. e5, 2018
882018
Functional characterization of SMARCA4 variants identified by targeted exome-sequencing of 131,668 cancer patients
TM Fernando, R Piskol, R Bainer, ES Sokol, SE Trabucco, Q Zhang, ...
Nature communications 11 (1), 5551, 2020
862020
Structural basis of an asymmetric condensin ATPase cycle
M Hassler, IA Shaltiel, M Kschonsak, B Simon, F Merkel, L Thärichen, ...
Molecular cell 74 (6), 1175-1188. e9, 2019
752019
A hold-and-feed mechanism drives directional DNA loop extrusion by condensin
IA Shaltiel, S Datta, L Lecomte, M Hassler, M Kschonsak, S Bravo, ...
Science 376 (6597), 1087-1094, 2022
732022
Structure of the Pds5-Scc1 complex and implications for cohesin function
KW Muir, M Kschonsak, Y Li, J Metz, CH Haering, D Panne
Cell reports 14 (9), 2116-2126, 2016
612016
Structure of the human sodium leak channel NALCN
M Kschonsak, HC Chua, CL Noland, C Weidling, T Clairfeuille, ...
Nature 587 (7833), 313-318, 2020
512020
Structures of HCMV Trimer reveal the basis for receptor recognition and cell entry
M Kschonsak, L Rougé, CP Arthur, H Hoangdung, N Patel, I Kim, ...
Cell 184 (5), 1232-1244. e16, 2021
492021
Structural architecture of the human NALCN channelosome
M Kschonsak, HC Chua, C Weidling, N Chakouri, CL Noland, K Schott, ...
Nature 603 (7899), 180-186, 2022
282022
Structural basis for HCMV Pentamer receptor recognition and antibody neutralization
M Kschonsak, MC Johnson, R Schelling, EM Green, L Rougé, H Ho, ...
Science advances 8 (10), eabm2536, 2022
232022
Cryoelectron microscopy structure of a yeast centromeric nucleosome at 2.7 Å resolution
D Migl, M Kschonsak, CP Arthur, Y Khin, SC Harrison, C Ciferri, ...
Structure 28 (3), 363-370. e3, 2020
202020
Structure-guided unlocking of NaX reveals a non-selective tetrodotoxin-sensitive cation channel
CL Noland, HC Chua, M Kschonsak, SA Heusser, N Braun, T Chang, ...
Nature Communications 13 (1), 1416, 2022
182022
Up-regulation of ubiquitin–proteasome activity upon loss of NatA-dependent N-terminal acetylation
I Kats, C Reinbold, M Kschonsak, A Khmelinskii, L Armbruster, T Ruppert, ...
Life science alliance 5 (2), 2022
162022
Cryo-EM reveals an unprecedented binding site for NaV1. 7 inhibitors enabling rational design of potent hybrid inhibitors
M Kschonsak, CC Jao, CP Arthur, AL Rohou, P Bergeron, DF Ortwine, ...
Elife 12, e84151, 2023
122023
Solution structure and flexibility of the condensin HEAT-repeat subunit Ycg1
K Manalastas-Cantos, M Kschonsak, CH Haering, DI Svergun
Journal of Biological Chemistry 294 (37), 13822-13829, 2019
122019
Ternary complex dissociation kinetics contribute to mutant-selective EGFR degradation
SC Rosenberg, F Shanahan, S Yamazoe, M Kschonsak, YJ Zeng, J Lee, ...
Cell Chemical Biology 30 (2), 175-187. e15, 2023
102023
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