| Glucagon-like peptide-1 and exendin-4 stimulate β-cell neogenesis in streptozotocin-treated newborn rats resulting in persistently improved glucose homeostasis at adult age C Tourrel, D Bailbe, MJ Meile, M Kergoat, B Portha Diabetes 50 (7), 1562-1570, 2001 | 489 | 2001 |
| IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat JA Ehses, G Lacraz, MH Giroix, F Schmidlin, J Coulaud, N Kassis, ... Proceedings of the National Academy of Sciences 106 (33), 13998-14003, 2009 | 427 | 2009 |
| Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the β-cell mass during the prediabetic period with glucagon-like peptide-1 or exendin-4 C Tourrel, D Bailbe, M Lacorne, MJ Meile, M Kergoat, B Portha Diabetes 51 (5), 1443-1452, 2002 | 398 | 2002 |
| Chromosomal mapping of genetic loci associated with non-insulin dependent diabetes in the GK rat D Gauguier, P Froguel, V Parent, C Bernard, MT Bihoreau, B Portha, ... Nature Genetics 12 (1), 38-43, 1996 | 373 | 1996 |
| Diabetogenic effect of streptozotocin in the rat during the perinatal period B Portha, C Levacher, L Picon, G Rosselin Diabetes 23 (11), 889-895, 1974 | 348 | 1974 |
| β-Cell insensitivity to glucose in the GK rat, a spontaneous nonobese model for type II diabetes B Portha, P Serradas, D Bailbé, KI Suzuki, Y Goto, MH Giroix Diabetes 40 (4), 486-491, 1991 | 337 | 1991 |
| Chemical diabetes in the adult rat as the spontaneous evolution of neonatal diabetes B Portha, L Picon, G Rosselin Diabetologia 17, 371-377, 1979 | 290 | 1979 |
| Islet inflammation and fibrosis in a spontaneous model of type 2 diabetes, the GK rat F Homo-Delarche, S Calderari, JC Irminger, MN Gangnerau, J Coulaud, ... Diabetes 55 (6), 1625-1633, 2006 | 240 | 2006 |
| The rat models of non-insulin dependent diabetes induced by neonatal streptozotocin. B Portha, O Blondel, P Serradas, R McEvoy, MH Giroix, M Kergoat, ... Diabète & métabolisme 15 (2), 61-75, 1989 | 240 | 1989 |
| Impaired development of pancreatic beta-cell mass is a primary event during the progression to diabetes in the GK rat J Movassat, C Saulnier, P Serradas, B Portha Diabetologia 40, 916-925, 1997 | 202 | 1997 |
| Glucose insensitivity and amino-acid hypersensitivity of insulin release in rats with non-insulin-dependent diabetes: a study with the perfused pancreas MH Giroix, B Portha, M Kergoat, D Bailbe, L Picon Diabetes 32 (5), 445-451, 1983 | 196 | 1983 |
| Programmed disorders of β‐cell development and function as one cause for type 2 diabetes? The GK rat paradigm B Portha Diabetes/metabolism research and reviews 21 (6), 495-504, 2005 | 195 | 2005 |
| Early‐life origins of type 2 diabetes: fetal programming of the beta‐cell mass B Portha, A Chavey, J Movassat Journal of Diabetes Research 2011 (1), 105076, 2011 | 178 | 2011 |
| Insulin resistance in the GK rat: decreased receptor number but normal kinase activity in liver S Bisbis, D Bailbe, MA Tormo, F Picarel-Blanchot, M Derouet, J Simon, ... American Journal of Physiology-Endocrinology and Metabolism 265 (5), E807-E813, 1993 | 168 | 1993 |
| GLP-1 based therapy for type 2 diabetes DK Arulmozhi, B Portha European journal of pharmaceutical sciences 28 (1-2), 96-108, 2006 | 149 | 2006 |
| The GK rat beta-cell: a prototype for the diseased human beta-cell in type 2 diabetes? B Portha, G Lacraz, M Kergoat, F Homo-Delarche, MH Giroix, D Bailbé, ... Molecular and cellular endocrinology 297 (1-2), 73-85, 2009 | 147 | 2009 |
| In vivo insulin resistance in streptozotocin-diabetic rats—evidence for reversal following oral vanadate treatment O Blondel, D Bailbe, B Portha Diabetologia 32, 185-190, 1989 | 144 | 1989 |
| beta-cell function and viability in the spontaneously diabetic GK rat: information from the GK/Par colony. B Portha, MH Giroix, P Serradas, MN Gangnerau, J Movassat, F Rajas, ... Diabetes 50 (suppl_1), S89, 2001 | 127 | 2001 |
| Histogenesis of the endocrine pancreas in newborn rats after destruction by streptozotocin: an immunocytochemical study D Cantenys, B Portha, MC Dutrillaux, E Hollande, C Roze, L Picon Virchows Archiv B 35, 109-122, 1980 | 125 | 1980 |
| The GK rat: a prototype for the study of non-overweight type 2 diabetes B Portha, MH Giroix, C Tourrel-Cuzin, H Le-Stunff, J Movassat animal models in diabetes research, 125-159, 2012 | 122 | 2012 |
