| Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration S Balaban, RF Shearer, LS Lee, M van Geldermalsen, M Schreuder, ... Cancer & metabolism 5, 1-14, 2017 | 358 | 2017 |
| TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes T Gudjonsson, M Altmeyer, V Savic, L Toledo, C Dinant, M Grøfte, ... Cell 150 (4), 697-709, 2012 | 358 | 2012 |
| Tyrosine phosphorylation profiling reveals the signaling network characteristics of Basal breast cancer cells F Hochgräfe, L Zhang, SA O'Toole, BC Browne, M Pinese, A Porta Cubas, ... Cancer research 70 (22), 9391-9401, 2010 | 210 | 2010 |
| Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer SA O'Toole, DA Machalek, RF Shearer, EKA Millar, R Nair, P Schofield, ... Cancer research 71 (11), 4002-4014, 2011 | 185 | 2011 |
| Functional roles of the E3 ubiquitin ligase UBR5 in cancer RF Shearer, M Iconomou, CKW Watts, DN Saunders Molecular Cancer Research 13 (12), 1523-1532, 2015 | 135 | 2015 |
| Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway DR Croucher, F Hochgräfe, L Zhang, L Liu, RJ Lyons, D Rickwood, ... Cancer research 73 (6), 1969-1980, 2013 | 99 | 2013 |
| ZUFSP deubiquitylates K63-linked polyubiquitin chains to promote genome stability P Haahr, N Borgermann, X Guo, D Typas, D Achuthankutty, S Hoffmann, ... Molecular Cell 70 (1), 165-174. e6, 2018 | 91 | 2018 |
| SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer NLE Harris, C Vennin, JRW Conway, KL Vine, M Pinese, MJ Cowley, ... Oncogene 36 (30), 4288-4298, 2017 | 89 | 2017 |
| Experimental design for stable genetic manipulation in mammalian cell lines: lentivirus and alternatives RF Shearer, DN Saunders Genes to Cells 20 (1), 1-10, 2015 | 88 | 2015 |
| Extracellular fatty acids are the major contributor to lipid synthesis in prostate cancer S Balaban, ZD Nassar, AY Zhang, E Hosseini-Beheshti, MM Centenera, ... Molecular Cancer Research 17 (4), 949-962, 2019 | 81 | 2019 |
| Intravital imaging to monitor therapeutic response in moving hypoxic regions resistant to PI3K pathway targeting in pancreatic cancer JRW Conway, SC Warren, D Herrmann, KJ Murphy, AS Cazet, C Vennin, ... Cell reports 23 (11), 3312-3326, 2018 | 67 | 2018 |
| Mitochondrial mutations and metabolic adaptation in pancreatic cancer RA Hardie, E Van Dam, M Cowley, TL Han, S Balaban, M Pajic, M Pinese, ... Cancer & metabolism 5, 1-15, 2017 | 64 | 2017 |
| Bimolecular complementation affinity purification (BiCAP) reveals dimer-specific protein interactions for ERBB2 dimers DR Croucher, M Iconomou, JF Hastings, SP Kennedy, JZR Han, ... Science signaling 9 (436), ra69-ra69, 2016 | 64 | 2016 |
| Heterogeneity of fatty acid metabolism in breast cancer cells underlies differential sensitivity to palmitate‐induced apoptosis S Balaban, LS Lee, B Varney, A Aishah, Q Gao, RF Shearer, ... Molecular oncology 12 (9), 1623-1638, 2018 | 52 | 2018 |
| SerpinB2 (PAI-2) modulates proteostasis via binding misfolded proteins and promotion of cytoprotective inclusion formation JA Lee, JJ Yerbury, N Farrawell, RF Shearer, P Constantinescu, ... PLoS One 10 (6), e0130136, 2015 | 45 | 2015 |
| Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer SP Kennedy, JZR Han, N Portman, M Nobis, JF Hastings, KJ Murphy, ... Breast Cancer Research 21, 1-17, 2019 | 44 | 2019 |
| Homo-and heterotypic association regulates signaling by the SgK269/PEAK1 and SgK223 pseudokinases L Liu, YW Phua, RS Lee, X Ma, Y Jenkins, K Novy, ES Humphrey, H Chan, ... Journal of Biological Chemistry 291 (41), 21571-21583, 2016 | 37 | 2016 |
| The E3 ubiquitin ligase UBR5 regulates centriolar satellite stability and primary cilia RF Shearer, KAM Frikstad, J McKenna, RA McCloy, N Deng, A Burgess, ... Molecular biology of the cell 29 (13), 1542-1554, 2018 | 34 | 2018 |
| Regulation of primary cilia formation by the ubiquitin–proteasome system RF Shearer, DN Saunders Biochemical Society Transactions 44 (5), 1265-1271, 2016 | 27 | 2016 |
| Pathogenic variants in SLF2 and SMC5 cause segmented chromosomes and mosaic variegated hyperploidy LJ Grange, JJ Reynolds, F Ullah, B Isidor, RF Shearer, X Latypova, ... Nature communications 13 (1), 6664, 2022 | 21 | 2022 |
