HER2 recruits AKT1 to disrupt STING signalling and suppress antiviral defence and antitumour immunity S Wu, Q Zhang, F Zhang, F Meng, S Liu, R Zhou, Q Wu, X Li, LI Shen, ... Nature cell biology 21 (8), 1027-1040, 2019 | 202 | 2019 |
Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade Q Zhang, F Meng, S Chen, SW Plouffe, S Wu, S Liu, X Li, R Zhou, J Wang, ... Nature cell biology 19 (4), 362-374, 2017 | 185 | 2017 |
A non-canonical cGAS–STING–PERK pathway facilitates the translational program critical for senescence and organ fibrosis D Zhang, Y Liu, Y Zhu, Q Zhang, H Guan, S Liu, S Chen, C Mei, C Chen, ... Nature cell biology 24 (5), 766-782, 2022 | 143 | 2022 |
Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation F Meng, R Zhou, S Wu, Q Zhang, Q Jin, Y Zhou, SW Plouffe, S Liu, ... Genes & Development 30 (9), 1086-1100, 2016 | 87 | 2016 |
Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity F Meng, Z Yu, D Zhang, S Chen, H Guan, R Zhou, Q Wu, Q Zhang, S Liu, ... Molecular Cell 81 (20), 4147-4164. e7, 2021 | 80 | 2021 |
IRF3 prevents colorectal tumorigenesis via inhibiting the nuclear translocation of β-catenin M Tian, X Wang, J Sun, W Lin, L Chen, S Liu, X Wu, L Shi, P Xu, X Cai, ... Nature Communications 11 (1), 5762, 2020 | 69 | 2020 |
TBK1-mediated DRP1 targeting confers nucleic acid sensing to reprogram mitochondrial dynamics and physiology S Chen, S Liu, J Wang, Q Wu, A Wang, H Guan, Q Zhang, D Zhang, ... Molecular Cell 80 (5), 810-827. e7, 2020 | 48 | 2020 |
Lck/Hck/Fgr-mediated tyrosine phosphorylation negatively regulates TBK1 to restrain innate antiviral responses S Liu, S Chen, X Li, S Wu, Q Zhang, Q Jin, L Hu, R Zhou, Z Yu, F Meng, ... Cell host & microbe 21 (6), 754-768. e5, 2017 | 40 | 2017 |
AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity Q Zhang, S Liu, CS Zhang, Q Wu, X Yu, R Zhou, F Meng, A Wang, ... Molecular Cell 82 (23), 4519-4536. e7, 2022 | 33 | 2022 |
The protein phosphatase PPM1A dephosphorylates and activates YAP to govern mammalian intestinal and liver regeneration R Zhou, Q Wu, M Wang, S Irani, X Li, Q Zhang, F Meng, S Liu, F Zhang, ... PLoS Biology 19 (2), e3001122, 2021 | 17 | 2021 |
Innate immune sensing of lysosomal dysfunction drives multiple lysosomal storage disorders A Wang, C Chen, C Mei, S Liu, C Xiang, W Fang, F Zhang, Y Xu, S Chen, ... Nature Cell Biology 26 (2), 219-234, 2024 | 15 | 2024 |
IRF3 activates RB to authorize cGAS-STING–induced senescence and mitigate liver fibrosis Q Wu, X Leng, Q Zhang, YZ Zhu, R Zhou, Y Liu, C Mei, D Zhang, S Liu, ... Science Advances 10 (9), eadj2102, 2024 | 13 | 2024 |
Targeting proteostasis of the HEV replicase to combat infection in preclinical models F Zhang, LD Xu, Q Zhang, A Wang, X Yu, S Liu, C Chen, S Wu, J Jin, ... Journal of Hepatology 78 (4), 704-716, 2023 | 12 | 2023 |
Advancements in tyrosine kinase-mediated regulation of innate nucleic acid sensing. S Liu, P Xu Zhejiang da xue xue bao. Yi xue ban= Journal of Zhejiang University. Medical …, 2024 | 1 | 2024 |
Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis X Li, X Li, C Xiang, J Cao, J Guo, S Zhu, J Tan, L Wang, C Gao, S Liu, ... Cell Reports 43 (9), 2024 | | 2024 |
Microglial cGAS–STING signaling underlies glaucoma pathogenesis Y Liu, A Wang, C Chen, Q Zhang, Q Shen, D Zhang, X Xiao, S Chen, ... Proceedings of the National Academy of Sciences 121 (36), e2409493121, 2024 | | 2024 |