Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to … S Xia, M Liu, C Wang, W Xu, Q Lan, S Feng, F Qi, L Bao, L Du, S Liu, ... Cell research 30 (4), 343-355, 2020 | 1377 | 2020 |
Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein S Xia, Y Zhu, M Liu, Q Lan, W Xu, Y Wu, T Ying, S Liu, Z Shi, S Jiang, L Lu Cellular & molecular immunology 17 (7), 765-767, 2020 | 791 | 2020 |
Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor L Lu, Q Liu, Y Zhu, KH Chan, L Qin, Y Li, Q Wang, JFW Chan, L Du, F Yu, ... Nature communications 5 (1), 3067, 2014 | 537 | 2014 |
The role of furin cleavage site in SARS-CoV-2 spike protein-mediated membrane fusion in the presence or absence of trypsin S Xia, Q Lan, S Su, X Wang, W Xu, Z Liu, Y Zhu, Q Wang, L Lu, S Jiang Signal transduction and targeted therapy 5 (1), 92, 2020 | 328 | 2020 |
Origin, virological features, immune evasion and intervention of SARS-CoV-2 Omicron sublineages S Xia, L Wang, Y Zhu, L Lu, S Jiang Signal Transduction and Targeted Therapy 7 (1), 241, 2022 | 123 | 2022 |
Minireview of progress in the structural study of SARS-CoV-2 proteins G Zhu, C Zhu, Y Zhu, F Sun Current research in microbial sciences 1, 53-61, 2020 | 65 | 2020 |
Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies MM Zhao, Y Zhu, L Zhang, G Zhong, L Tai, S Liu, G Yin, J Lu, Q He, MJ Li, ... Cell discovery 8 (1), 53, 2022 | 56 | 2022 |
Surface exposure of the HIV-1 env cytoplasmic tail LLP2 domain during the membrane fusion process: interaction with gp41 fusion core L Lu, Y Zhu, J Huang, X Chen, H Yang, S Jiang, YH Chen Journal of Biological Chemistry 283 (24), 16723-16731, 2008 | 53 | 2008 |
Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation S Xia, Q Lan, Y Zhu, C Wang, W Xu, Y Li, L Wang, F Jiao, J Zhou, C Hua, ... Signal Transduction and Targeted Therapy 6 (1), 288, 2021 | 44 | 2021 |
Characterization by high-resolution crystal structure analysis of a triple-helix region of human collagen type III with potent cell adhesion activity C Hua, Y Zhu, W Xu, S Ye, R Zhang, L Lu, S Jiang Biochemical and biophysical research communications 508 (4), 1018-1023, 2019 | 43 | 2019 |
Improved pharmacological and structural properties of HIV fusion inhibitor AP3 over enfuvirtide: highlighting advantages of artificial peptide strategy X Zhu, Y Zhu, S Ye, Q Wang, W Xu, S Su, Z Sun, F Yu, Q Liu, C Wang, ... Scientific reports 5 (1), 13028, 2015 | 43 | 2015 |
Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement Y Chen, X Song, S Ye, L Miao, Y Zhu, RG Zhang, G Ji Protein & cell 4, 299-309, 2013 | 43 | 2013 |
Crystal structure of kindlin-2 PH domain reveals a conformational transition for its membrane anchoring and regulation of integrin activation Y Liu, Y Zhu, S Ye, R Zhang Protein & cell 3 (6), 434-440, 2012 | 40 | 2012 |
Nanometer-resolution in situ structure of the SARS-CoV-2 postfusion spike protein L Tai, G Zhu, M Yang, L Cao, X Xing, G Yin, C Chan, C Qin, Z Rao, ... Proceedings of the National Academy of Sciences 118 (48), e2112703118, 2021 | 39 | 2021 |
Pan-coronavirus fusion inhibitors as the hope for today and tomorrow X Wang, S Xia, Y Zhu, L Lu, S Jiang Protein & cell 12 (2), 84-88, 2021 | 38 | 2021 |
Intravaginal administration of human type III collagen-derived biomaterial with high cell-adhesion activity to treat vaginal atrophy in rats S You, S Liu, X Dong, H Li, Y Zhu, L Hu ACS Biomaterials Science & Engineering 6 (4), 1977-1988, 2020 | 32 | 2020 |
A randomized open-label clinical trial of an anti-HPV biological dressing (JB01-BD) administered intravaginally to treat high-risk HPV infection X Guo, L Qiu, Y Wang, Y Wang, Q Wang, L Song, Y Li, K Huang, X Du, ... Microbes and Infection 18 (2), 148-152, 2016 | 30 | 2016 |
A cryo-electron microscopy support film formed by 2D crystals of hydrophobin HFBI H Fan, B Wang, Y Zhang, Y Zhu, B Song, H Xu, Y Zhai, M Qiao, F Sun Nature communications 12 (1), 7257, 2021 | 29 | 2021 |
Structure-based evidence for the enhanced transmissibility of the dominant SARS-CoV-2 B. 1.1. 7 variant (Alpha) S Xia, Z Wen, L Wang, Q Lan, F Jiao, L Tai, Q Wang, F Sun, S Jiang, L Lu, ... Cell discovery 7 (1), 109, 2021 | 28 | 2021 |
A novel HIV-1 gp41 tripartite model for rational design of HIV-1 fusion inhibitors with improved antiviral activity S Su, Q Wang, W Xu, F Yu, C Hua, Y Zhu, S Jiang, L Lu AIDS 31 (7), 885-894, 2017 | 27 | 2017 |