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Yun Zhu
Yun Zhu
在 ibp.ac.cn 的电子邮件经过验证
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Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to …
S Xia, M Liu, C Wang, W Xu, Q Lan, S Feng, F Qi, L Bao, L Du, S Liu, ...
Cell research 30 (4), 343-355, 2020
13772020
Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein
S Xia, Y Zhu, M Liu, Q Lan, W Xu, Y Wu, T Ying, S Liu, Z Shi, S Jiang, L Lu
Cellular & molecular immunology 17 (7), 765-767, 2020
7912020
Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor
L Lu, Q Liu, Y Zhu, KH Chan, L Qin, Y Li, Q Wang, JFW Chan, L Du, F Yu, ...
Nature communications 5 (1), 3067, 2014
5372014
The role of furin cleavage site in SARS-CoV-2 spike protein-mediated membrane fusion in the presence or absence of trypsin
S Xia, Q Lan, S Su, X Wang, W Xu, Z Liu, Y Zhu, Q Wang, L Lu, S Jiang
Signal transduction and targeted therapy 5 (1), 92, 2020
3282020
Origin, virological features, immune evasion and intervention of SARS-CoV-2 Omicron sublineages
S Xia, L Wang, Y Zhu, L Lu, S Jiang
Signal Transduction and Targeted Therapy 7 (1), 241, 2022
1232022
Minireview of progress in the structural study of SARS-CoV-2 proteins
G Zhu, C Zhu, Y Zhu, F Sun
Current research in microbial sciences 1, 53-61, 2020
652020
Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies
MM Zhao, Y Zhu, L Zhang, G Zhong, L Tai, S Liu, G Yin, J Lu, Q He, MJ Li, ...
Cell discovery 8 (1), 53, 2022
562022
Surface exposure of the HIV-1 env cytoplasmic tail LLP2 domain during the membrane fusion process: interaction with gp41 fusion core
L Lu, Y Zhu, J Huang, X Chen, H Yang, S Jiang, YH Chen
Journal of Biological Chemistry 283 (24), 16723-16731, 2008
532008
Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation
S Xia, Q Lan, Y Zhu, C Wang, W Xu, Y Li, L Wang, F Jiao, J Zhou, C Hua, ...
Signal Transduction and Targeted Therapy 6 (1), 288, 2021
442021
Characterization by high-resolution crystal structure analysis of a triple-helix region of human collagen type III with potent cell adhesion activity
C Hua, Y Zhu, W Xu, S Ye, R Zhang, L Lu, S Jiang
Biochemical and biophysical research communications 508 (4), 1018-1023, 2019
432019
Improved pharmacological and structural properties of HIV fusion inhibitor AP3 over enfuvirtide: highlighting advantages of artificial peptide strategy
X Zhu, Y Zhu, S Ye, Q Wang, W Xu, S Su, Z Sun, F Yu, Q Liu, C Wang, ...
Scientific reports 5 (1), 13028, 2015
432015
Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement
Y Chen, X Song, S Ye, L Miao, Y Zhu, RG Zhang, G Ji
Protein & cell 4, 299-309, 2013
432013
Crystal structure of kindlin-2 PH domain reveals a conformational transition for its membrane anchoring and regulation of integrin activation
Y Liu, Y Zhu, S Ye, R Zhang
Protein & cell 3 (6), 434-440, 2012
402012
Nanometer-resolution in situ structure of the SARS-CoV-2 postfusion spike protein
L Tai, G Zhu, M Yang, L Cao, X Xing, G Yin, C Chan, C Qin, Z Rao, ...
Proceedings of the National Academy of Sciences 118 (48), e2112703118, 2021
392021
Pan-coronavirus fusion inhibitors as the hope for today and tomorrow
X Wang, S Xia, Y Zhu, L Lu, S Jiang
Protein & cell 12 (2), 84-88, 2021
382021
Intravaginal administration of human type III collagen-derived biomaterial with high cell-adhesion activity to treat vaginal atrophy in rats
S You, S Liu, X Dong, H Li, Y Zhu, L Hu
ACS Biomaterials Science & Engineering 6 (4), 1977-1988, 2020
322020
A randomized open-label clinical trial of an anti-HPV biological dressing (JB01-BD) administered intravaginally to treat high-risk HPV infection
X Guo, L Qiu, Y Wang, Y Wang, Q Wang, L Song, Y Li, K Huang, X Du, ...
Microbes and Infection 18 (2), 148-152, 2016
302016
A cryo-electron microscopy support film formed by 2D crystals of hydrophobin HFBI
H Fan, B Wang, Y Zhang, Y Zhu, B Song, H Xu, Y Zhai, M Qiao, F Sun
Nature communications 12 (1), 7257, 2021
292021
Structure-based evidence for the enhanced transmissibility of the dominant SARS-CoV-2 B. 1.1. 7 variant (Alpha)
S Xia, Z Wen, L Wang, Q Lan, F Jiao, L Tai, Q Wang, F Sun, S Jiang, L Lu, ...
Cell discovery 7 (1), 109, 2021
282021
A novel HIV-1 gp41 tripartite model for rational design of HIV-1 fusion inhibitors with improved antiviral activity
S Su, Q Wang, W Xu, F Yu, C Hua, Y Zhu, S Jiang, L Lu
AIDS 31 (7), 885-894, 2017
272017
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