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Yoonji Lee
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Oxidative modifications of glyceraldehyde-3-phosphate dehydrogenase play a key role in its multiple cellular functions
NR Hwang, SH Yim, YM Kim, J Jeong, EJ Song, Y Lee, JH Lee, S Choi, ...
Biochemical Journal 423 (2), 253-264, 2009
1942009
In Vivo Albumin Traps Photosensitizer Monomers from Self-Assembled Phthalocyanine Nanovesicles: A Facile and Switchable Theranostic Approach
X Li, S Yu, Y Lee, T Guo, N Kwon, D Lee, SC Yeom, Y Cho, G Kim, ...
Journal of the American Chemical Society 141 (3), 1366-1372, 2018
1632018
Capsiate, a nonpungent capsaicin-like compound, inhibits angiogenesis and vascular permeability via a direct inhibition of Src kinase activity
BJ Pyun, S Choi, Y Lee, TW Kim, JK Min, Y Kim, BD Kim, JH Kim, TY Kim, ...
Cancer research 68 (1), 227-235, 2008
1062008
Recent advances in structure-based drug design targeting class AG protein-coupled receptors utilizing crystal structures and computational simulations
Y Lee, S Basith, S Choi
Journal of medicinal chemistry 61 (1), 1-46, 2018
992018
Herbal compound farnesiferol C exerts antiangiogenic and antitumor activity and targets multiple aspects of VEGFR1 (Flt1) or VEGFR2 (Flk1) signaling cascades
JH Lee, S Choi, Y Lee, HJ Lee, KH Kim, KS Ahn, H Bae, HJ Lee, EO Lee, ...
Molecular cancer therapeutics 9 (2), 389-399, 2010
902010
Transient receptor potential vanilloid type 1 antagonists: a patent review (2011-2014)
Y Lee, S Hong, M Cui, PK Sharma, J Lee, S Choi
Expert opinion on therapeutic patents 25 (3), 291-318, 2015
792015
Structural insights into transient receptor potential vanilloid type 1 (TRPV1) from homology modeling, flexible docking, and mutational studies
JH Lee, Y Lee, HC Ryu, DW Kang, J Lee, J Lazar, LV Pearce, ...
Journal of computer-aided molecular design 25, 317-327, 2011
792011
Mapping the intramolecular signal transduction of G‐protein coupled receptors
Y Lee, S Choi, C Hyeon
Proteins: Structure, Function, and Bioinformatics 82 (5), 727-743, 2014
592014
A novel pyrazole derivative protects from ovariectomy-induced osteoporosis through the inhibition of NADPH oxidase
JH Joo, JE Huh, JH Lee, DR Park, Y Lee, SG Lee, S Choi, HJ Lee, ...
Scientific reports 6 (1), 22389, 2016
552016
X-ray Crystal Structure and Binding Mode Analysis of Human S-Adenosylhomocysteine Hydrolase Complexed with Novel Mechanism-Based Inhibitors, Haloneplanocin A Analogues
KM Lee, WJ Choi, Y Lee, HJ Lee, LX Zhao, HW Lee, JG Park, HO Kim, ...
Journal of medicinal chemistry 54 (4), 930-938, 2011
502011
Structure–Activity Relationships of Truncated C2-or C8-Substituted Adenosine Derivatives as Dual Acting A2A and A3 Adenosine Receptor Ligands
X Hou, MS Majik, K Kim, Y Pyee, Y Lee, V Alexander, HJ Chung, HW Lee, ...
Journal of medicinal chemistry 55 (1), 342-356, 2011
442011
Structure–Activity Relationships of Neplanocin A Analogues as S-Adenosylhomocysteine Hydrolase Inhibitors and Their Antiviral and Antitumor Activities
G Chandra, YW Moon, Y Lee, JY Jang, J Song, A Nayak, K Oh, ...
Journal of medicinal chemistry 58 (12), 5108-5120, 2015
432015
8-hydroxy-2-deoxyguanosine prevents plaque formation and inhibits vascular smooth muscle cell activation through Rac1 inactivation
J Young Huh, D Son, Y Lee, J Lee, B Kim, H Myung Lee, H Jo, S Choi, ...
Free Radical Biology and Medicine, 2012
432012
Importance of protein dynamics in the structure-based drug discovery of class AG protein-coupled receptors (GPCRs)
Y Lee, R Lazim, SJY Macalino, S Choi
Current opinion in structural biology 55, 147-153, 2019
402019
Water-Soluble Phthalocyanines Selectively Bind to Albumin Dimers: A Green Approach Toward Enhancing Tumor-Targeted Photodynamic Therapy
X Li, K Jeong, Y Lee, T Guo, D Lee, J Park, N Kwon, JH Na, SK Hong, ...
Theranostics 9 (22), 6412-6423, 2019
362019
Ultraslow Water-Mediated Transmembrane Interactions Regulate the Activation of A 2A Adenosine Receptor
Y Lee, S Kim, S Choi, C Hyeon
Biophysical Journal 111 (6), 1180-1191, 2016
362016
Communication over the network of binary switches regulates the activation of A2A adenosine receptor
Y Lee, S Choi, C Hyeon
PLoS computational biology 11 (2), e1004044, 2015
352015
Revolutionizing Medicinal Chemistry: The Application of Artificial Intelligence (AI) in Early Drug Discovery
R Han, H Yoon, G Kim, H Lee, Y Lee
Pharmaceuticals 16 (9), 1259, 2023
302023
Synthesis and Anti-Renal Fibrosis Activity of Conformationally Locked Truncated 2-Hexynyl-N 6-Substituted-(N)-Methanocarba-nucleosides as A3 Adenosine Receptor Antagonists and …
A Nayak, G Chandra, I Hwang, K Kim, X Hou, HO Kim, PK Sahu, KK Roy, ...
Journal of medicinal chemistry 57 (4), 1344-1354, 2014
262014
Structural prerequisites for CRM1-dependent nuclear export signaling peptides: accessibility, adapting conformation, and the stability at the binding site
Y Lee, J Pei, JM Baumhardt, YM Chook, NV Grishin
Scientific reports 9 (1), 6627, 2019
252019
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