Drug resistance and treatment failure in leishmaniasis: A 21st century challenge A Ponte-Sucre, F Gamarro, JC Dujardin, MP Barrett, R López-Vélez, ... PLoS neglected tropical diseases 11 (12), e0006052, 2017 | 783 | 2017 |
Population genomics reveals the origin and asexual evolution of human infective trypanosomes W Weir, P Capewell, B Foth, C Clucas, A Pountain, P Steketee, N Veitch, ... elife 5, e11473, 2016 | 94 | 2016 |
Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana R Mwenechanya, J Kovářová, NJ Dickens, M Mudaliar, P Herzyk, ... PLoS neglected tropical diseases 11 (6), e0005649, 2017 | 58 | 2017 |
Genomic instability at the locus of sterol C24-methyltransferase promotes amphotericin B resistance in Leishmania parasites AW Pountain, SK Weidt, C Regnault, PA Bates, AM Donachie, NJ Dickens, ... PLoS Neglected Tropical Diseases 13 (2), e0007052, 2019 | 50 | 2019 |
Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli KM Rattigan, AW Pountain, C Regnault, F Achcar, IM Vincent, ... PloS one 13 (3), e0194126, 2018 | 46 | 2018 |
Deletion of transketolase triggers a stringent metabolic response in promastigotes and loss of virulence in amastigotes of Leishmania mexicana J Kovářová, AW Pountain, D Wildridge, S Weidt, F Bringaud, ... PLoS Pathogens 14 (3), e1006953, 2018 | 21 | 2018 |
Amphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism and oxidative stress response EA Alpizar-Sosa, NRB Ithnin, W Wei, AW Pountain, SK Weidt, ... PLoS Neglected Tropical Diseases 16 (9), e0010779, 2022 | 20 | 2022 |
Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs F Giordani, D Paape, IM Vincent, AW Pountain, F Fernández-Cortés, ... PLoS pathogens 16 (11), e1008932, 2020 | 19 | 2020 |
The paralogous transcription factors Stp1 and Stp2 of Candida albicans have distinct functions in nutrient acquisition and host interaction P Miramón, AW Pountain, A van Hoof, MC Lorenz Infection and immunity 88 (5), 10.1128/iai. 00763-19, 2020 | 15 | 2020 |
Untargeted metabolomics to understand the basis of phenotypic differences in amphotericin B-resistant Leishmania parasites AW Pountain, MP Barrett Wellcome Open Research 4, 2019 | 13 | 2019 |
Interactions of Both Pathogenic and Nonpathogenic CUG Clade Candida Species with Macrophages Share a Conserved Transcriptional Landscape AW Pountain, JR Collette, WM Farrell, MC Lorenz Mbio 12 (6), e03317-21, 2021 | 11 | 2021 |
Iminosugars counteract the downregulation of the interferon γ receptor by dengue virus JL Miller, ML Hill, J Brun, A Pountain, AC Sayce, N Zitzmann Antiviral Research 170, 104551, 2019 | 11 | 2019 |
The tempo and mode of gene regulatory programs during bacterial infection G Avital, F Kuperwaser, AW Pountain, KA Lacey, EE Zwack, M Podkowik, ... Cell reports 41 (2), 2022 | 5 | 2022 |
A quantitative model for the transcriptional landscape of the bacterial cell cycle A Pountain, P Jiang, M Podkowik, B Shopsin, VJ Torres, I Yanai bioRxiv, 2022 | 4 | 2022 |
Quorum-sensing agr system of Staphylococcus aureus primes gene expression for protection from lethal oxidative stress M Podkowik, AI Perault, G Putzel, A Pountain, J Kim, AL DuMont, ... Elife 12, RP89098, 2024 | 3 | 2024 |
Transcription–replication interactions reveal bacterial genome regulation AW Pountain, P Jiang, T Yao, E Homaee, Y Guan, KJC McDonald, ... Nature 626 (7999), 661-669, 2024 | 3 | 2024 |
Candida auris—macrophage cellular interactions and transcriptional response P Miramón, AW Pountain, MC Lorenz Infection and Immunity 91 (11), e00274-23, 2023 | 3 | 2023 |
Transcription-replication interactions reveal principles of bacterial genome regulation AW Pountain, P Jiang, T Yao, E Homaee, Y Guan, M Podkowik, ... Research Square, 2022 | 1 | 2022 |
Quorum-sensing M Podkowik, AI Perault, G Putzel, A Pountain, J Kim, AL DuMont, ... | | 2024 |
Genetic and metabolic mechanisms of amphotericin B resistance in Leishmania parasites AW Pountain University of Glasgow, 2018 | | 2018 |