| The systemin receptor SR160 from Lycopersicon peruvianum is a member of the LRR receptor kinase family JM Scheer, CA Ryan Jr Proceedings of the National Academy of Sciences 99 (14), 9585-9590, 2002 | 384 | 2002 |
| Anti-CD20/CD3 T cell–dependent bispecific antibody for the treatment of B cell malignancies LL Sun, D Ellerman, M Mathieu, M Hristopoulos, X Chen, Y Li, X Yan, ... Science translational medicine 7 (287), 287ra70-287ra70, 2015 | 262 | 2015 |
| Polypeptide hormones CA Ryan, G Pearce, J Scheer, DS Moura The Plant Cell 14 (suppl_1), S251-S264, 2002 | 237 | 2002 |
| Bispecific antibodies with natural architecture produced by co-culture of bacteria expressing two distinct half-antibodies C Spiess, M Merchant, A Huang, Z Zheng, NY Yang, J Peng, D Ellerman, ... Nature biotechnology 31 (8), 753-758, 2013 | 221 | 2013 |
| A common allosteric site and mechanism in caspases JM Scheer, MJ Romanowski, JA Wells Proceedings of the National Academy of Sciences 103 (20), 7595-7600, 2006 | 189 | 2006 |
| A 160-kD Systemin Receptor on the Surface of Lycopersicon peruvianum Suspension-Cultured Cells JM Scheer, CA Ryan The plant cell 11 (8), 1525-1535, 1999 | 187 | 1999 |
| Antitumor efficacy of a bispecific antibody that targets HER2 and activates T cells TT Junttila, J Li, J Johnston, M Hristopoulos, R Clark, D Ellerman, ... Cancer research 74 (19), 5561-5571, 2014 | 168 | 2014 |
| Production of heteromultimeric proteins J Scheer, C Spiess, DG Yansura US Patent 9,637,557, 2017 | 164 | 2017 |
| Development of a two-part strategy to identify a therapeutic human bispecific antibody that inhibits IgE receptor signaling J Jackman, Y Chen, A Huang, B Moffat, JM Scheer, SR Leong, WP Lee, ... Journal of Biological Chemistry 285 (27), 20850-20859, 2010 | 125 | 2010 |
| Crystal structure of procaspase-1 zymogen domain reveals insight into inflammatory caspase autoactivation JM Elliott, L Rouge, C Wiesmann, JM Scheer Journal of Biological Chemistry 284 (10), 6546-6553, 2009 | 111 | 2009 |
| Development of a human IgG4 bispecific antibody for dual targeting of interleukin-4 (IL-4) and interleukin-13 (IL-13) cytokines C Spiess, J Bevers, J Jackman, N Chiang, G Nakamura, M Dillon, H Liu, ... Journal of Biological Chemistry 288 (37), 26583-26593, 2013 | 99 | 2013 |
| An allosteric circuit in caspase-1 D Datta, JM Scheer, MJ Romanowski, JA Wells Journal of molecular biology 381 (5), 1157-1167, 2008 | 90 | 2008 |
| Knobs-into-holes antibody production in mammalian cell lines reveals that asymmetric afucosylation is sufficient for full antibody-dependent cellular cytotoxicity W Shatz, S Chung, B Li, B Marshall, M Tejada, W Phung, W Sandoval, ... MAbs 5 (6), 872-881, 2013 | 86 | 2013 |
| Generation of systemin signaling in tobacco by transformation with the tomato systemin receptor kinase gene JM Scheer, G Pearce, CA Ryan Proceedings of the National Academy of Sciences 100 (17), 10114-10117, 2003 | 85 | 2003 |
| Suramin inhibits initiation of defense signaling by systemin, chitosan, and a β-glucan elicitor in suspension-cultured Lycopersicon peruvianum cells J Stratmann, J Scheer, CA Ryan Proceedings of the National Academy of Sciences 97 (16), 8862-8867, 2000 | 82 | 2000 |
| X chromosome-linked inhibitor of apoptosis regulates cell death induction by proapoptotic receptor agonists E Varfolomeev, B Alicke, JM Elliott, K Zobel, K West, H Wong, JM Scheer, ... Journal of Biological Chemistry 284 (50), 34553-34560, 2009 | 77 | 2009 |
| Design and pharmacokinetic characterization of novel antibody formats for ocular therapeutics K Gadkar, CV Pastuskovas, JE Le Couter, JM Elliott, J Zhang, CV Lee, ... Investigative Ophthalmology & Visual Science 56 (9), 5390-5400, 2015 | 74 | 2015 |
| Contribution of antibody hydrodynamic size to vitreal clearance revealed through rabbit studies using a species-matched fab W Shatz, PE Hass, M Mathieu, HS Kim, K Leach, M Zhou, Y Crawford, ... Molecular Pharmaceutics 13 (9), 2996-3003, 2016 | 73 | 2016 |
| Crystal structures of a ligand-free and malonate-bound human caspase-1: implications for the mechanism of substrate binding MJ Romanowski, JM Scheer, T O'Brien, RS McDowell Structure 12 (8), 1361-1371, 2004 | 72 | 2004 |
| A bispecific DLL3/CD3 IgG-like T-cell engaging antibody induces antitumor responses in small cell lung cancer S Hipp, V Voynov, B Drobits-Handl, C Giragossian, F Trapani, AE Nixon, ... Clinical Cancer Research 26 (19), 5258-5268, 2020 | 70 | 2020 |
Robert F. KelleyGenentech, Inc.在 gene.com 的电子邮件经过验证
Robert F. KelleyGenentech, Inc.在 gene.com 的电子邮件经过验证