| The zebrafish reference genome sequence and its relationship to the human genome K Howe, MD Clark, CF Torroja, J Torrance, C Berthelot, M Muffato, ... Nature 496 (7446), 498-503, 2013 | 5160 | 2013 |
| Metastasis and immune evasion from extracellular cGAMP hydrolysis J Li, MA Duran, N Dhanota, WK Chatila, SE Bettigole, J Kwon, RK Sriram, ... Cancer discovery 11 (5), 1212-1227, 2021 | 178 | 2021 |
| A robust multiplex immunofluorescence and digital pathology workflow for the characterisation of the tumour immune microenvironment A Viratham Pulsawatdi, SG Craig, V Bingham, K McCombe, ... Molecular oncology 14 (10), 2384-2402, 2020 | 87 | 2020 |
| QuPath: The global impact of an open source digital pathology system MP Humphries, P Maxwell, M Salto-Tellez Computational and Structural Biotechnology Journal 19, 852-859, 2021 | 76 | 2021 |
| Identifying mismatch repair‐deficient colon cancer: near‐perfect concordance between immunohistochemistry and microsatellite instability testing in a large, population‐based series MB Loughrey, J McGrath, HG Coleman, P Bankhead, P Maxwell, ... Histopathology 78 (3), 401-413, 2021 | 68 | 2021 |
| Characterisation of male breast cancer: a descriptive biomarker study from a large patient series MP Humphries, S Sundara Rajan, H Honarpisheh, G Cserni, J Dent, ... Scientific reports 7 (1), 45293, 2017 | 64 | 2017 |
| Immune status is prognostic for poor survival in colorectal cancer patients and is associated with tumour hypoxia SG Craig, MP Humphries, M Alderdice, V Bingham, SD Richman, ... British journal of cancer 123 (8), 1280-1288, 2020 | 60 | 2020 |
| Automated tumour recognition and digital pathology scoring unravels new role for PD‐L1 in predicting good outcome in ER‐/HER2+ breast cancer MP Humphries, S Hynes, V Bingham, D Cougot, J James, F Patel-Socha, ... Journal of Oncology 2018 (1), 2937012, 2018 | 53 | 2018 |
| Obesity and male breast cancer: provocative parallels? MP Humphries, VC Jordan, V Speirs BMC medicine 13, 1-9, 2015 | 51 | 2015 |
| Critical appraisal of programmed death ligand 1 reflex diagnostic testing: current standards and future opportunities MP Humphries, S McQuaid, SG Craig, V Bingham, P Maxwell, M Maurya, ... Journal of Thoracic Oncology 14 (1), 45-53, 2019 | 47 | 2019 |
| Improving the diagnostic accuracy of the PD-L1 test with image analysis and multiplex hybridization MP Humphries, V Bingham, F Abdullahi Sidi, SG Craig, S McQuaid, ... Cancers 12 (5), 1114, 2020 | 38 | 2020 |
| The adaptive immune and immune checkpoint landscape of neoadjuvant treated esophageal adenocarcinoma using digital pathology quantitation MP Humphries, SG Craig, R Kacprzyk, NC Fisher, V Bingham, S McQuaid, ... BMC cancer 20, 1-11, 2020 | 30 | 2020 |
| Triazoloacridin-6-ones as novel inhibitors of the quinone oxidoreductases NQO1 and NQO2 KA Nolan, MP Humphries, J Barnes, JR Doncaster, MC Caraher, N Tirelli, ... Bioorganic & medicinal chemistry 18 (2), 696-706, 2010 | 27 | 2010 |
| Novel inhibitors of NRH: quinone oxidoreductase 2 (NQO2): crystal structures, biochemical activity, and intracellular effects of imidazoacridin-6-ones MS Dunstan, J Barnes, M Humphries, RC Whitehead, RA Bryce, D Leys, ... Journal of medicinal chemistry 54 (19), 6597-6611, 2011 | 25 | 2011 |
| The clinical and molecular significance associated with STING signaling in breast cancer EE Parkes, MP Humphries, E Gilmore, FA Sidi, V Bingham, SM Phyu, ... NPJ Breast Cancer 7 (1), 81, 2021 | 23 | 2021 |
| Comparison of different anti‐Ki67 antibody clones and hot‐spot sizes for assessing proliferative index and grading in pancreatic neuroendocrine tumours using manual and image … R Owens, E Gilmore, V Bingham, C Cardwell, H McBride, S McQuaid, ... Histopathology 77 (4), 646-658, 2020 | 23 | 2020 |
| Deregulation of IGF-binding proteins-2 and-5 contributes to the development of endocrine resistant breast cancer in vitro Y Hawsawi, MP Humphries, A Wright, A Berwick, M Shires, H Al-Kharobi, ... Oncotarget 7 (22), 32129, 2016 | 22 | 2016 |
| Imidazoacridin-6-ones as novel inhibitors of the quinone oxidoreductase NQO2 KA Nolan, MP Humphries, RA Bryce, IJ Stratford Bioorganic & Medicinal Chemistry Letters 20 (9), 2832-2836, 2010 | 21 | 2010 |
| Activation of a cGAS-STING-mediated immune response predicts response to neoadjuvant chemotherapy in early breast cancer EE Parkes, KI Savage, T Lioe, C Boyd, S Halliday, SM Walker, K Lowry, ... British journal of cancer 126 (2), 247-258, 2022 | 20 | 2022 |
| A means of assessing deep learning-based detection of ICOS protein expression in colon cancer MMK Sarker, Y Makhlouf, SG Craig, MP Humphries, M Loughrey, ... Cancers 13 (15), 3825, 2021 | 20 | 2021 |
