| The bacterial defensin resistance protein MprF consists of separable domains for lipid lysinylation and antimicrobial peptide repulsion CM Ernst, P Staubitz, NN Mishra, SJ Yang, G Hornig, H Kalbacher, ... PLoS pathogens 5 (11), e1000660, 2009 | 369 | 2009 |
| Broad‐spectrum antimicrobial peptide resistance by MprF‐mediated aminoacylation and flipping of phospholipids CM Ernst, A Peschel Molecular microbiology 80 (2), 290-299, 2011 | 244 | 2011 |
| Adaptive evolution of virulence and persistence in carbapenem-resistant Klebsiella pneumoniae CM Ernst, JR Braxton, CA Rodriguez-Osorio, AP Zagieboylo, L Li, ... Nature medicine 26 (5), 705-711, 2020 | 184 | 2020 |
| Multi-institute analysis of carbapenem resistance reveals remarkable diversity, unexplained mechanisms, and limited clonal outbreaks GC Cerqueira, AM Earl, CM Ernst, YH Grad, JP Dekker, M Feldgarden, ... Proceedings of the National Academy of Sciences 114 (5), 1135-1140, 2017 | 166 | 2017 |
| Multiple peptide resistance factor (MprF)-mediated resistance of Staphylococcus aureus against antimicrobial peptides coincides with a modulated peptide interaction with … J Andrä, T Goldmann, CM Ernst, A Peschel, T Gutsmann Journal of Biological Chemistry 286 (21), 18692-18700, 2011 | 124 | 2011 |
| Characterization of Staphylococcus aureus cardiolipin synthases 1 and 2 and their contribution to accumulation of cardiolipin in stationary phase and within phagocytes T Koprivnjak, D Zhang, CM Ernst, A Peschel, WM Nauseef, JP Weiss Journal of bacteriology 193 (16), 4134-4142, 2011 | 94 | 2011 |
| MprF-mediated daptomycin resistance CM Ernst, A Peschel International Journal of Medical Microbiology 309 (5), 359-363, 2019 | 76 | 2019 |
| Gain-of-function mutations in the phospholipid flippase MprF confer specific daptomycin resistance CM Ernst, CJ Slavetinsky, S Kuhn, JN Hauser, M Nega, NN Mishra, ... MBio 9 (6), 10.1128/mbio. 01659-18, 2018 | 75 | 2018 |
| Alanyl-phosphatidylglycerol and lysyl-phosphatidylglycerol are translocated by the same MprF flippases and have similar capacities to protect against the antibiotic daptomycin … CJ Slavetinsky, A Peschel, CM Ernst Antimicrobial agents and chemotherapy 56 (7), 3492-3497, 2012 | 75 | 2012 |
| The lipid-modifying multiple peptide resistance factor is an oligomer consisting of distinct interacting synthase and flippase subunits CM Ernst, S Kuhn, CJ Slavetinsky, B Krismer, S Heilbronner, C Gekeler, ... MBio 6 (1), 10.1128/mbio. 02340-14, 2015 | 72 | 2015 |
| Changing the phospholipid composition of Staphylococcus aureus causes distinct changes in membrane proteome and membrane‐sensory regulators S Sievers, C M. Ernst, T Geiger, M Hecker, C Wolz, D Becher, A Peschel Proteomics 10 (8), 1685-1693, 2010 | 38 | 2010 |
| Sensitizing Staphylococcus aureus to antibacterial agents by decoding and blocking the lipid flippase MprF CJ Slavetinsky, JN Hauser, C Gekeler, J Slavetinsky, A Geyer, A Kraus, ... Elife 11, e66376, 2022 | 28 | 2022 |
| Generation of mouse-zebrafish hematopoietic tissue chimeric embryos for hematopoiesis and host-pathogen interaction studies M Parada-Kusz, C Penaranda, EJ Hagedorn, A Clatworthy, AV Nair, ... Disease Models & Mechanisms 11 (11), dmm034876, 2018 | 24 | 2018 |
| Genetic determinants facilitating the evolution of resistance to carbapenem antibiotics P Ma, LL He, A Pironti, HH Laibinis, CM Ernst, AL Manson, ... Elife 10, e67310, 2021 | 19 | 2021 |
| Carbapenem resistance caused by high-level expression of OXA-663 β-lactamase in an OmpK36-deficient Klebsiella pneumoniae clinical isolate P Ma, HH Laibinis, CM Ernst, DT Hung Antimicrobial agents and chemotherapy 62 (11), 10.1128/aac. 01281-18, 2018 | 17 | 2018 |
| SensitizingStaphylococcus aureusto antibacterial host defense by decoding and blocking the lipid flippase MprF CJ Slavetinsky, JN Hauser, C Gekeler, J Slavetinsky, A Geyer, A Kraus, ... | 4 | 2020 |
| Prokaryotic phospholipid translocation by ubiquitous PplT domain proteins JN Hauser, AK Tchoupa, S Zabel, K Nieselt, C Ernst, CJ Slavetinsky, ... bio Rxiv, 2022 | | 2022 |
| Compounds, compositions, and methods for inducing antimicrobial intracellular activity and for preventing and treating microbial infections DT Hung, CM Ernst, T Kawate WO Patent 2023/086671 A1, 2022 | | 2022 |
| Anti-staphylococcal antibodies CM Ernst, AP Peschel, A Kraus, M Tesar US Patent 9,873,733, 2018 | | 2018 |
| Carbapenem resistance caused by high-level expression of OXA-663 β-lactamase in an OmpK36-deficient Klebsiella pneumoniae clinical isolate. MPJ Ma PeiJun, HH Laibinis, CM Ernst, DT Hung | | 2018 |
