| Control of regulatory T cell development by the transcription factor Foxp3 S Hori, T Nomura, S Sakaguchi Science 299 (5609), 1057-1061, 2003 | 10645 | 2003 |
| Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various … S Sakaguchi, N Sakaguchi, M Asano, M Itoh, M Toda Journal of immunology (Baltimore, Md.: 1950) 155 (3), 1151-1164, 1995 | 9314 | 1995 |
| Regulatory T cells and immune tolerance S Sakaguchi, T Yamaguchi, T Nomura, M Ono cell 133 (5), 775-787, 2008 | 5679 | 2008 |
| Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses S Sakaguchi Annu. Rev. Immunol. 22, 531-562, 2004 | 4462 | 2004 |
| Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self S Sakaguchi Nature immunology 6 (4), 345-352, 2005 | 3530 | 2005 |
| CTLA-4 control over Foxp3+ regulatory T cell function K Wing, Y Onishi, P Prieto-Martin, T Yamaguchi, M Miyara, Z Fehervari, ... Science 322 (5899), 271-275, 2008 | 3253 | 2008 |
| Immunologic Self-Tolerance Maintained by Cd25+Cd4+Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4 T Takahashi, T Tagami, S Yamazaki, T Uede, J Shimizu, N Sakaguchi, ... The Journal of experimental medicine 192 (2), 303-310, 2000 | 2753 | 2000 |
| FOXP3+ regulatory T cells in the human immune system S Sakaguchi, M Miyara, CM Costantino, DA Hafler Nature Reviews Immunology 10 (7), 490-500, 2010 | 2691 | 2010 |
| Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota K Atarashi, T Tanoue, K Oshima, W Suda, Y Nagano, H Nishikawa, ... Nature 500 (7461), 232-236, 2013 | 2642 | 2013 |
| Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor M Miyara, Y Yoshioka, A Kitoh, T Shima, K Wing, A Niwa, C Parizot, ... Immunity 30 (6), 899-911, 2009 | 2313 | 2009 |
| Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance J Shimizu, S Yamazaki, T Takahashi, Y Ishida, S Sakaguchi Nature immunology 3 (2), 135-142, 2002 | 2274 | 2002 |
| Regulatory T cells: key controllers of immunologic self-tolerance S Sakaguchi Cell 101 (5), 455-458, 2000 | 2199 | 2000 |
| Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance S Sakaguchi, N Sakaguchi, J Shimizu, S Yamazaki, T Sakihama, M Itoh, ... Immunological reviews 182 (1), 18-32, 2001 | 2114 | 2001 |
| Immunologic self-tolerance maintained by CD25+ CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. T Takahashi, Y Kuniyasu, M Toda, N Sakaguchi, M Itoh, M Iwata, ... International immunology 10 (12), 1969-1980, 1998 | 2029 | 1998 |
| Foxp3+CD25+CD4+ natural regulatory T cells in dominant self‐tolerance and autoimmune disease S Sakaguchi, M Ono, R Setoguchi, H Yagi, S Hori, Z Fehervari, J Shimizu, ... Immunological reviews 212 (1), 8-27, 2006 | 1951 | 2006 |
| Induction of tumor immunity by removing CD25+ CD4+ T cells: a common basis between tumor immunity and autoimmunity J Shimizu, S Yamazaki, S Sakaguchi The Journal of Immunology 163 (10), 5211-5218, 1999 | 1862 | 1999 |
| Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. M Asano, M Toda, N Sakaguchi, S Sakaguchi The Journal of experimental medicine 184 (2), 387-396, 1996 | 1789 | 1996 |
| Regulatory T cells in transplantation tolerance KJ Wood, S Sakaguchi Nature Reviews Immunology 3 (3), 199-210, 2003 | 1693 | 2003 |
| Thymus and autoimmunity: production of CD25+ CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance M Itoh, T Takahashi, N Sakaguchi, Y Kuniyasu, J Shimizu, F Otsuka, ... The Journal of Immunology 162 (9), 5317-5326, 1999 | 1636 | 1999 |
| A promoter-level mammalian expression atlas Nature 507 (7493), 462-470, 2014 | 1558 | 2014 |
