The voltage-gated potassium channel Kv1. 3 is a promising multitherapeutic target against human pathologies M Perez-Verdaguer, J Capera, C Serrano-Novillo, I Estadella, D Sastre, ... Expert opinion on therapeutic targets 20 (5), 577-591, 2016 | 106 | 2016 |
Fighting rheumatoid arthritis: Kv1. 3 as a therapeutic target A Serrano-Albarrás, S Cirera-Rocosa, D Sastre, I Estadella, A Felipe Biochemical pharmacology 165, 214-220, 2019 | 27 | 2019 |
The calmodulin‐binding tetraleucine motif of KCNE4 is responsible for association with Kv1. 3 L Sole, SR Roig, D Sastre, A Vallejo-Gracia, A Serrano-Albarrás, ... The FASEB Journal 33 (7), 8263-8279, 2019 | 13 | 2019 |
Calmodulin-dependent KCNE4 dimerization controls membrane targeting SR Roig, L Solé, S Cassinelli, M Colomer-Molera, D Sastre, ... Scientific reports 11 (1), 14046, 2021 | 10 | 2021 |
Triple-colocalization approach to assess traffic patterns and their modulation D Sastre, I Estadella, M Bosch, A Felipe Computer Optimized Microscopy: Methods and Protocols, 215-233, 2019 | 10 | 2019 |
KCNE4-dependent functional consequences of Kv1. 3-related leukocyte physiology A Vallejo-Gracia, D Sastre, M Colomer-Molera, L Solé, M Navarro-Pérez, ... Scientific reports 11 (1), 14632, 2021 | 9 | 2021 |
Functional consequences of the variable stoichiometry of the Kv1. 3-KCNE4 complex L Solé, D Sastre, M Colomer-Molera, A Vallejo-Gracia, SR Roig, ... Cells 9 (5), 1128, 2020 | 5 | 2020 |
A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes M Chan, H Sahakyan, J Eldstrom, D Sastre, Y Wang, Y Dou, M Pourrier, ... Elife 12, RP87038, 2023 | 2 | 2023 |
Kv1. 3-dependent immune system activation is regulated by KCNE4 M Colomer-Molera, D Sastre, LS Codina, A Vallejo-Gracia, MN Perez, ... Biophysical Journal 122 (3), 14a, 2023 | 1 | 2023 |
KCNE4-dependent modulation of Kv1. 3 pharmacology D Sastre, M Colomer-Molera, A de Benito-Bueno, C Valenzuela, ... Biochemical Pharmacology, 116368, 2024 | | 2024 |
Voltage Clamp Fluorometry: Illuminating the Dynamics of Ion Channels D Sastre, D Fedida Potassium Channels: Methods and Protocols, 119-138, 2024 | | 2024 |
Routing of Kv7. 1 to endoplasmic reticulum plasma membrane junctions C Serrano‐Novillo, I Estadella, M Navarro‐Pérez, A Oliveras, ... Acta Physiologica 240 (3), e14106, 2024 | | 2024 |
Impact of KCNE4 on Kv1. 3 pharmacology D Sastre, M Colomer-Molera, G Fernandez-Ballester, A Felipe Biophysical Journal 123 (3), 262a, 2024 | | 2024 |
Evaluating sequential and allosteric activation models in IKs channels with mutated voltage sensors D Fedida, D Sastre, Y Dou, M Westhoff, J Eldstrom Journal of General Physiology 156 (3), e202313465, 2024 | | 2024 |
KV1. 3 Interacts with a Calmodulin-Binding Tetraleucine Motif of KCNE4 D Sastre, LS Codina, SR Roig, G Fernandez-Ballester, MM Tamkun, ... Biophysical Journal 118 (3), 262a, 2020 | | 2020 |
The C-Terminal Domain of Kv1. 3 Interacts with KCNE4 to form Oligomeric Channels SR Roig, L Solé, A Vallejo-Gracia, D Sastre, A Serrano-Albarrás, ... Biophysical Journal 112 (3), 545a, 2017 | | 2017 |
EGF and the potassium channel Kv1. 3 are promising pharmacological targets against neuro-degenerative diseases R Martínez-Mármol, M Salla-Martret, D Sastre, I Estadella, A Felipe Journal of Neurology & Neuromedicine 1 (5), 2016 | | 2016 |
CHANGES IN THE KV1. 3 PHARMACOLOGY UPON THE ASSOCIATION WITH KCNE4 M Colomer-Molera, D Sastre, G Fernández-Ballester, A Felipe IX CONGRESO DE LA RED ESPAÑOLA DE CANALES IÓNICOS (RECI), 57, 0 | | |