| Structural model of the dimeric Parkinson’s protein LRRK2 reveals a compact architecture involving distant interdomain contacts G Guaitoli, F Raimondi, BK Gilsbach, Y Gómez-Llorente, E Deyaert, ... Proceedings of the National Academy of Sciences 113 (30), E4357-E4366, 2016 | 163 | 2016 |
| Phosphopeptide analysis reveals two discrete clusters of phosphorylation in the N-terminus and the Roc domain of the Parkinson-disease associated protein kinase LRRK2 CJ Gloeckner, K Boldt, F Von Zweydorf, S Helm, L Wiesent, H Sarioglu, ... Journal of proteome research 9 (4), 1738-1745, 2010 | 154 | 2010 |
| Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3 K Muda, D Bertinetti, F Gesellchen, JS Hermann, F von Zweydorf, ... Proceedings of the National Academy of Sciences 111 (1), E34-E43, 2014 | 147 | 2014 |
| Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated by its C-terminal WD40 domain G Piccoli, F Onofri, MD Cirnaru, CJO Kaiser, P Jagtap, A Kastenmüller, ... Molecular and cellular biology, 2014 | 123 | 2014 |
| The LRRK2 G2385R variant is a partial loss-of-function mutation that affects synaptic vesicle trafficking through altered protein interactions MDP Carrion, S Marsicano, F Daniele, A Marte, F Pischedda, ... Scientific reports 7 (1), 5377, 2017 | 59 | 2017 |
| Physiological and pathophysiological characteristics of ataxin-3 isoforms D Weishäupl, J Schneider, BP Pinheiro, C Ruess, SM Dold, ... Journal of Biological Chemistry 294 (2), 644-661, 2019 | 48 | 2019 |
| Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43 J Garcia Morato, F Hans, F von Zweydorf, R Feederle, SJ Elsässer, ... Nature Communications 13 (1), 1223, 2022 | 45 | 2022 |
| Identification and characterization of ubiquitinylation sites in TAR DNA-binding protein of 43 kDa (TDP-43) F Hans, M Eckert, F von Zweydorf, CJ Gloeckner, PJ Kahle Journal of Biological Chemistry 293 (41), 16083-16099, 2018 | 43 | 2018 |
| Medin aggregation causes cerebrovascular dysfunction in aging wild-type mice K Degenhardt, J Wagner, A Skodras, M Candlish, AJ Koppelmann, K Wild, ... Proceedings of the National Academy of Sciences 117 (38), 23925-23931, 2020 | 31 | 2020 |
| Allosteric inhibition of Parkinson’s-linked LRRK2 by constrained peptides LG Helton, A Soliman, F von Zweydorf, M Kentros, JT Manschwetus, ... ACS chemical biology 16 (11), 2326-2338, 2021 | 29 | 2021 |
| Antagonistic activities of CDC14B and CDK1 on USP9X regulate WT1-dependent mitotic transcription and survival M Dietachmayr, A Rathakrishnan, O Karpiuk, F von Zweydorf, T Engleitner, ... Nature communications 11 (1), 1268, 2020 | 29 | 2020 |
| Phosphorylation modulates the subcellular localization of SOX11 EA Balta, MT Wittmann, M Jung, E Sock, BM Haeberle, B Heim, ... Frontiers in molecular neuroscience 11, 211, 2018 | 26 | 2018 |
| Nanobodies as allosteric modulators of Parkinson’s disease–associated LRRK2 RK Singh, A Soliman, G Guaitoli, E Störmer, F von Zweydorf, T Dal Maso, ... Proceedings of the National Academy of Sciences 119 (9), e2112712119, 2022 | 23 | 2022 |
| Understanding the role of genetic variability in LRRK2 in Indian population A Kishore, A Ashok Kumar Sreelatha, M Sturm, F von‐Zweydorf, ... Movement Disorders 34 (4), 496-505, 2019 | 13 | 2019 |
| The LRRK2 N-terminal domain influences vesicle trafficking: impact of the E193K variant A Marku, MDP Carrion, F Pischedda, A Marte, Z Casiraghi, P Marciani, ... Scientific reports 10 (1), 3799, 2020 | 12 | 2020 |
| Phosphorylation of the neurogenic transcription factor SOX11 on serine 133 modulates neuronal morphogenesis EA Balta, I Schäffner, MT Wittmann, E Sock, F von Zweydorf, ... Scientific reports 8 (1), 16196, 2018 | 11 | 2018 |
| TRAF6 phosphorylation prevents its autophagic degradation and re-shapes LPS-triggered signaling networks J Busch, R Moreno, L de la Vega, VV Saul, S Bacher, F von Zweydorf, ... Cancers 13 (14), 3618, 2021 | 6 | 2021 |
| Applying SILAC for the differential analysis of protein complexes K Boldt, CJ Gloeckner, Y Texier, F von Zweydorf, M Ueffing Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) Methods and …, 2014 | 4 | 2014 |
| Biophysical analysis reveals autophosphorylation as an important negative regulator of LRRK2 dimerization G Guaitoli, X Zhang, F Saitta, P Miglionico, LM Silbermann, FY Ho, ... BioRxiv, 2023.08. 11.549911, 2023 | 2 | 2023 |
| Medin amyloid forms age‐associated aggregates in the brain vasculature and may contribute to cerebral β‐amyloidosis: Molecular and cell biology/APP/Abeta/amyloid J Wagner, K Degenhardt, K Wild, U Obermüller, LM Haesler, ... Alzheimer's & Dementia 16, e042861, 2020 | | 2020 |
