Progress and challenges in targeting the SARS-CoV-2 papain-like protease H Tan, Y Hu, P Jadhav, B Tan, J Wang Journal of medicinal chemistry 65 (11), 7561-7580, 2022 | 106 | 2022 |
SARS-CoV-2 main protease drug design, assay development, and drug resistance studies B Tan, R Joyce, H Tan, Y Hu, J Wang Accounts of chemical research 56 (2), 157-168, 2022 | 52 | 2022 |
Total syntheses of calyciphylline A-type alkaloids (−)-10-deoxydaphnipaxianine A,(+)-daphlongamine E and (+)-calyciphylline R via late-stage divinyl carbinol rearrangements Y Zhang, Y Chen, M Song, B Tan, Y Jiang, C Yan, Y Jiang, X Hu, C Zhang, ... Journal of the American Chemical Society 144 (35), 16042-16051, 2022 | 29 | 2022 |
Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model B Tan, X Zhang, A Ansari, P Jadhav, H Tan, K Li, A Chopra, A Ford, X Chi, ... Science 383 (6690), 1434-1440, 2024 | 22 | 2024 |
Exploring diverse reactive warheads for the design of SARS-CoV-2 main protease inhibitors B Tan, M Sacco, H Tan, K Li, R Joyce, X Zhang, Y Chen, J Wang European Journal of Medicinal Chemistry 259, 115667, 2023 | 17 | 2023 |
Design, synthesis and biological activity evaluation of novel 4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl) oxy) pyridine-2-yl) amino derivatives as potent … B Tan, X Zhang, X Quan, G Zheng, X Li, L Zhao, W Li, B Li Bioorganic & Medicinal Chemistry Letters 30 (16), 127339, 2020 | 13 | 2020 |
Structure-based design of SARS-CoV-2 papain-like protease inhibitors P Jadhav, B Huang, J Osipiuk, X Zhang, H Tan, C Tesar, M Endres, ... European Journal of Medicinal Chemistry 264, 116011, 2024 | 7 | 2024 |
Stereospecific Effects of Benzimidazolonepiperidine Compounds on T-Type Ca2+ Channels and Pain K Gomez, C Tang, B Tan, S Perez-Miller, D Ran, S Loya, ... ACS Chemical Neuroscience 13 (13), 2035-2047, 2022 | 4 | 2022 |
Structure-Based Lead Optimization of Enterovirus D68 2A Protease Inhibitors B Tan, C Liu, K Li, P Jadhav, G Lambrinidis, L Zhu, L Olson, H Tan, Y Wen, ... Journal of medicinal chemistry 66 (21), 14544-14563, 2023 | 1 | 2023 |