Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies ITW Harley, KM Kaufman, CD Langefeld, JB Harley, JA Kelly Nature Reviews Genetics 10 (5), 285-290, 2009 | 363 | 2009 |
IL‐17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice ITW Harley, TE Stankiewicz, DA Giles, S Softic, LM Flick, M Cappelletti, ... Hepatology 59 (5), 1830-1839, 2014 | 259 | 2014 |
Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease YY Gu, ITW Harley, LB Henderson, BJ Aronow, I Vietor, LA Huber, ... Nature 458 (7241), 1039-1042, 2009 | 163 | 2009 |
The curiously suspicious: a role for Epstein-Barr virus in lupus JB Harley, ITW Harley, JM Guthridge, JA James Lupus 15 (11), 768-777, 2006 | 129 | 2006 |
GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network B Namjou, T Lingren, Y Huang, S Parameswaran, BL Cobb, IB Stanaway, ... BMC medicine 17, 1-19, 2019 | 126 | 2019 |
Genetic associations of LYN with systemic lupus erythematosus R Lu, GS Vidal, JA Kelly, AM Delgado-Vega, XK Howard, SR Macwana, ... Genes & Immunity 10 (5), 397-403, 2009 | 126 | 2009 |
Obesity and the gut microbiome: Striving for causality ITW Harley, CL Karp Molecular metabolism 1 (1-2), 21-31, 2012 | 115 | 2012 |
Distinct Tlr4-expressing cell compartments control neutrophilic and eosinophilic airway inflammation JW McAlees, GS Whitehead, ITW Harley, M Cappelletti, CL Rewerts, ... Mucosal immunology 8 (4), 863-873, 2015 | 98 | 2015 |
Osteopontin and systemic lupus erythematosus association: a probable gene-gender interaction S Han, JM Guthridge, ITW Harley, AL Sestak, X Kim-Howard, ... PloS one 3 (3), e0001757, 2008 | 96 | 2008 |
Two functional lupus-associated BLK promoter variants control cell-type-and developmental-stage-specific transcription JM Guthridge, R Lu, H Sun, C Sun, GB Wiley, N Dominguez, ... The American Journal of Human Genetics 94 (4), 586-598, 2014 | 71 | 2014 |
Type I interferons regulate susceptibility to inflammation-induced preterm birth M Cappelletti, P Presicce, MJ Lawson, V Chaturvedi, TE Stankiewicz, ... JCI insight 2 (5), 2017 | 65 | 2017 |
SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression G Hou, ITW Harley, X Lu, T Zhou, N Xu, C Yao, Y Qin, Y Ouyang, J Ma, ... Nature communications 12 (1), 135, 2021 | 60 | 2021 |
The role of genetic variation near interferon-kappa in systemic lupus erythematosus ITW Harley, TB Niewold, RM Stormont, KM Kaufman, SB Glenn, ... BioMed Research International 2010, 2010 | 60 | 2010 |
Evaluation of TRAF6 in a large multiancestral lupus cohort B Namjou, CB Choi, ITW Harley, ME Alarcón‐Riquelme, ... Arthritis & Rheumatism 64 (6), 1960-1969, 2012 | 59 | 2012 |
Lysosomal pH Is Regulated in a Sex Dependent Manner in Immune Cells Expressing CXorf21 VM Harris, ITW Harley, BT Kurien, KA Koelsch, RH Scofield Frontiers in immunology 10, 578, 2019 | 46 | 2019 |
Identification of ATPAF1 as a novel candidate gene for asthma in children EM Schauberger, SL Ewart, SH Arshad, M Huebner, W Karmaus, ... Journal of Allergy and Clinical Immunology 128 (4), 753-760. e11, 2011 | 40 | 2011 |
Characterization of cxorf21 provides molecular insight into female-bias immune response in SLE pathogenesis VM Harris, KA Koelsch, BT Kurien, ITW Harley, JD Wren, JB Harley, ... Frontiers in immunology 10, 2160, 2019 | 39 | 2019 |
Lupus risk variants in the PXK locus alter B-cell receptor internalization SE Vaughn, C Foley, X Lu, ZH Patel, EE Zoller, AF Magnusen, ... Frontiers in genetics 5, 450, 2015 | 37 | 2015 |
Differential colonization with segmented filamentous bacteria and Lactobacillus murinus do not drive divergent development of diet-induced obesity in C57BL/6 mice ITW Harley, DA Giles, PT Pfluger, SL Burgess, S Walters, J Hembree, ... Molecular metabolism 2 (3), 171-183, 2013 | 37 | 2013 |
The Effect of Inversion at 8p23 on BLK Association with Lupus in Caucasian Population B Namjou, Y Ni, ITW Harley, I Chepelev, B Cobb, LC Kottyan, PM Gaffney, ... PloS one 9 (12), e115614, 2014 | 36 | 2014 |