Large scale analysis of the mutational landscape in HT-SELEX improves aptamer discovery J Hoinka, A Berezhnoy, P Dao, ZE Sauna, E Gilboa, TM Przytycka Nucleic acids research 43 (12), 5699-5707, 2015 | 134 | 2015 |
Identification of sequence–structure RNA binding motifs for SELEX-derived aptamers J Hoinka, E Zotenko, A Friedman, ZE Sauna, TM Przytycka Bioinformatics 28 (12), i215-i223, 2012 | 107 | 2012 |
Aptacluster–a method to cluster ht-selex aptamer pools and lessons from its application J Hoinka, A Berezhnoy, ZE Sauna, E Gilboa, TM Przytycka Research in Computational Molecular Biology: 18th Annual International …, 2014 | 103 | 2014 |
Identifying high-affinity aptamer ligands with defined cross-reactivity using high-throughput guided systematic evolution of ligands by exponential enrichment A Levay, R Brenneman, J Hoinka, D Sant, M Cardone, G Trinchieri, ... Nucleic acids research 43 (12), e82-e82, 2015 | 78 | 2015 |
AptaSUITE: a full-featured bioinformatics framework for the comprehensive analysis of aptamers from HT-SELEX experiments J Hoinka, R Backofen, TM Przytycka Molecular Therapy-Nucleic Acids 11, 515-517, 2018 | 76 | 2018 |
AptaTRACE elucidates RNA sequence-structure motifs from selection trends in HT-SELEX experiments P Dao, J Hoinka, M Takahashi, J Zhou, M Ho, Y Wang, F Costa, JJ Rossi, ... Cell systems 3 (1), 62-70, 2016 | 73 | 2016 |
Highly Constrained Bicyclic Scaffolds for the Discovery of Protease-Stable Peptides via mRNA Display DE Hacker, J Hoinka, ES Iqbal, TM Przytycka, MCT Hartman ACS chemical biology 12 (3), 795-804, 2017 | 66 | 2017 |
A 2′ FY-RNA motif defines an aptamer for Ebolavirus secreted protein S Shubham, J Hoinka, S Banerjee, E Swanson, JA Dillard, ... Scientific reports 8 (1), 12373, 2018 | 39 | 2018 |
AptaPLEX–A dedicated, multithreaded demultiplexer for HT-SELEX data J Hoinka, T Przytycka Methods 106, 82-85, 2016 | 33 | 2016 |
Direct, competitive comparison of linear, monocyclic, and bicyclic libraries using mRNA display DE Hacker, NA Abrigo, J Hoinka, SL Richardson, TM Przytycka, ... ACS Combinatorial Science 22 (6), 306-310, 2020 | 21 | 2020 |
AptaGUI—a graphical user interface for the efficient analysis of HT-SELEX data J Hoinka, P Dao, TM Przytycka Molecular Therapy-Nucleic Acids 4, 2015 | 19 | 2015 |
Co-SELECT reveals sequence non-specific contribution of DNA shape to transcription factor binding in vitro S Pal, J Hoinka, TM Przytycka Nucleic acids research 47 (13), 6632-6641, 2019 | 15 | 2019 |
Subpopulation detection and their comparative analysis across single-cell experiments with scPopCorn Y Wang, J Hoinka, TM Przytycka Cell systems 8 (6), 506-513. e5, 2019 | 15 | 2019 |
AptaBlocks: Designing RNA complexes and accelerating RNA-based drug delivery systems Y Wang, J Hoinka, Y Liang, T Adamus, P Swiderski, TM Przytycka Nucleic acids research 46 (16), 8133-8142, 2018 | 11 | 2018 |
RepairSig: Deconvolution of DNA damage and repair contributions to the mutational landscape of cancer D Wojtowicz, J Hoinka, B Amgalan, YA Kim, TM Przytycka Cell Systems 12 (10), 994-1003. e4, 2021 | 9 | 2021 |
The Bioinformatics of Aptamers: HT-SELEX Analysis with AptaSUITE J Hoinka, TM Przytycka Nucleic Acid Aptamers: Selection, Characterization, and Application, 73-83, 2022 | 2 | 2022 |
DNA aptamers for early detection of ebolavirus S Banerjee, J Hoinka, A Gosai, Z Zhu, S Devarakonda, C Geekiyanage, ... The FASEB Journal 35, 2021 | 2 | 2021 |
Embedding gene sets in low-dimensional space J Hoinka, TM Przytycka Nature Machine Intelligence 2 (7), 367-368, 2020 | 2 | 2020 |
Co-SELECT reveals sequence non-specific contribution of DNA shape to transcription factor binding in vitro S Pal, J Hoinka, TM Przytycka BioRxiv, 413922, 2018 | 2 | 2018 |
AptaTRACE: Elucidating Sequence-Structure Binding Motifs by Uncovering Selection Trends in HT-SELEX Experiments P Dao, J Hoinka, Y Wang, M Takahashi, J Zhou, F Costa, J Rossi, ... arXiv preprint arXiv:1604.03081, 2016 | 2 | 2016 |