FTY720/Fingolimod Reduces Synucleinopathy and Improves Gut Motility in A53T Mice CONTRIBUTIONS OF PRO-BRAIN-DERIVED NEUROTROPHIC FACTOR (PRO-BDNF) AND MATURE BDNF G Vidal-Martínez, J Vargas-Medrano, C Gil-Tommee, D Medina, NT Garza, ... Journal of Biological Chemistry 191 (39), 20811–20821, 2016 | 76 | 2016 |
FTY720 (Fingolimod) reverses α-synuclein-induced downregulation of brain-derived neurotrophic factor mRNA in OLN-93 oligodendroglial cells I Segura-Ulate, B Yang, J Vargas-Medrano, RG Perez Neuropharmacology 117, 149-157, 2017 | 40 | 2017 |
Novel FTY720-based compounds stimulate neurotrophin expression and phosphatase activity in dopaminergic cells J Vargas-Medrano, S Krishnamachari, E Villanueva, WH Godfrey, H Lou, ... ACS Medicinal Chemistry Letters 5 (7), 782-786, 2014 | 36 | 2014 |
FTY720 improves behavior, increases brain derived neurotrophic factor levels and reduces α-synuclein pathology in parkinsonian GM2+/− mice G Vidal-Martinez, K Najera, JD Miranda, C Gil-Tommee, B Yang, ... Neuroscience 411, 1-10, 2019 | 34 | 2019 |
Psychological and neurobiological aspects of suicide in adolescents: Current outlooks J Vargas-Medrano, V Diaz-Pacheco, C Castaneda, M Miranda-Arango, ... Brain, behavior, & immunity-health 7, 100124, 2020 | 29 | 2020 |
PKCβ-dependent phosphorylation of the glycine transporter 1 J Vargas-Medrano, V Castrejon-Tellez, F Plenge, I Ramirez, M Miranda Neurochemistry international 59 (8), 1123-1132, 2011 | 28 | 2011 |
Altered levels of interleukins and neurotrophic growth factors in mood disorders and suicidality: an analysis from periphery to central nervous system PMT Bharathi S Gadad, Javier Vargas-Medrano, Enrique Ivan Ramos, Katherine ... Translational Psychiatry 11 (1), 341, 2021 | 25 | 2021 |
FTY720-Mitoxy reduces synucleinopathy and neuroinflammation, restores behavior and mitochondria function, and increases GDNF expression in Multiple System Atrophy mouse models G Vidal-Martinez, I Segura-Ulate, B Yang, V Diaz-Pacheco, JA Barragan, ... Experimental neurology 325, 113120, 2020 | 20 | 2020 |
FTY720-Mitoxy reduces toxicity associated with MSA-like α-synuclein and oxidative stress by increasing trophic factor expression and myelin protein in OLN-93 oligodendroglia … J Vargas-Medrano, I Segura-Ulate, B Yang, R Chinnasamy, JB Arterburn, ... Neuropharmacology 158, 107701, 2019 | 19 | 2019 |
Up-regulation of protective neuronal MicroRNAs by FTY720 and novel FTY720-derivatives J Vargas-Medrano, B Yang, NT Garza, I Segura-Ulate, RG Perez Neuroscience letters 690, 178-180, 2019 | 19 | 2019 |
PKC-dependent GlyT1 ubiquitination occurs independent of phosphorylation: Inespecificity in lysine selection for ubiquitination SP Barrera, V Castrejon-Tellez, M Trinidad, E Robles-Escajeda, ... PLoS One 10 (9), e0138897, 2015 | 18 | 2015 |
Is gratitude associated with suicidal ideation in veterans with mental illness and student veterans with PTSD symptoms? E Umucu, CL Lo, B Lee, J Vargas-Medrano, V Diaz-Pacheco, K Misra, ... The Journal of nervous and mental disease 210 (1), 26-31, 2022 | 16 | 2022 |
Could α-Synuclein modulation of insulin and dopamine identify a novel link between Parkinson’s disease and diabetes as well as potential therapies? G Vidal-Martinez, B Yang, J Vargas-Medrano, RG Perez Frontiers in Molecular Neuroscience 11, 465, 2018 | 13 | 2018 |
Parkinsonian GM2 synthase knockout mice lacking mature gangliosides develop urinary dysfunction and neurogenic bladder C Gil-Tommee, G Vidal-Martinez, CA Reyes, J Vargas-Medrano, ... Experimental neurology 311, 265-273, 2019 | 12 | 2019 |
FTY720-Derivatives Do Not Induce FTY720-Like Lymphopenia I Segura-Ulate, T Belcher, G Vidal-Martinez, J Vargas-Medrano, RG Perez Journal of Pharmacological Sciences, 2017 | 11 | 2017 |
Chlorpromazine and dimethyl sulfoxide modulate the catalytic activity of the plasma membrane Ca2+-ATPase from human erythrocyte F Plenge-Tellechea, CA Domínguez-Solís, ÁG Díaz-Sánchez, ... Journal of Bioenergetics and Biomembranes, 1-11, 2018 | 10 | 2018 |
Cypermethrin, deltamethrin and glyphosate affect the activity of the Ca2+-ATPase from human erythrocyte J Vargas-Medrano, JA Sierra-Fonseca, M Arellano-Carrillo, ... Tecnociencia chihuahua 5 (3), 121-131, 2011 | 9 | 2011 |
Autophagy induction and accumulation of phosphorylated tau in the hippocampus and prefrontal cortex of adult C57BL/6 mice subjected to adolescent fluoxetine treatment JA Sierra-Fonseca, M Rodriguez, A Themann, O Lira, FJ Flores-Ramirez, ... Journal of Alzheimer's Disease 83 (4), 1691-1702, 2021 | 7 | 2021 |
Recombinant α- β- and γ-Synucleins Stimulate Protein Phosphatase 2A Catalytic Subunit Activity in Cell Free Assays S Lek, J Vargas-Medrano, E Villanueva, B Marcus, W Godfrey, RG Perez Journal of Visualized Experiments 126, 1-7, 2017 | 6 | 2017 |
EFECTO TÓXICO DE LOS PLAGUICIDAS AGRÍCOLAS SOBRE LA RELAJACIÓN MUSCULAR. Estudio de la Ca2+-ATPasa de retículo sarcoplásmico (SERCA) LF Plenge-Tellechea, J Vargas-Medrano Ciencia en la frontera 2 (1), 75-79, 2003 | 5 | 2003 |