Antigen-specific adaptive immunity to SARS-CoV-2 in acute COVID-19 and associations with age and disease severity CR Moderbacher, SI Ramirez, JM Dan, A Grifoni, KM Hastie, D Weiskopf, ... Cell 183 (4), 996-1012. e19, 2020 | 1829 | 2020 |
Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model TF Rogers, F Zhao, D Huang, N Beutler, A Burns, W He, O Limbo, C Smith, ... Science 369 (6506), 956-963, 2020 | 1378 | 2020 |
Immunological mechanisms of the antitumor effects of supplemental oxygenation SM Hatfield, J Kjaergaard, D Lukashev, TH Schreiber, B Belikoff, R Abbott, ... Science translational medicine 7 (277), 277ra30-277ra30, 2015 | 563 | 2015 |
Precursor frequency and affinity determine B cell competitive fitness in germinal centers, tested with germline-targeting HIV vaccine immunogens RK Abbott, JH Lee, S Menis, P Skog, M Rossi, T Ota, DW Kulp, D Bhullar, ... Immunity 48 (1), 133-146. e6, 2018 | 309 | 2018 |
Engineered immunogen binding to alum adjuvant enhances humoral immunity TJ Moyer, Y Kato, W Abraham, JYH Chang, DW Kulp, N Watson, ... Nature Medicine 26 (3), 430-440, 2020 | 227 | 2020 |
Hostile, hypoxia–A2-adenosinergic tumor biology as the next barrier to overcome for tumor immunologists MV Sitkovsky, S Hatfield, R Abbott, B Belikoff, D Lukashev, A Ohta Cancer immunology research 2 (7), 598-605, 2014 | 220 | 2014 |
Systemic oxygenation weakens the hypoxia and hypoxia inducible factor 1α-dependent and extracellular adenosine-mediated tumor protection SM Hatfield, J Kjaergaard, D Lukashev, B Belikoff, TH Schreiber, ... Journal of molecular medicine 92, 1283-1292, 2014 | 196 | 2014 |
Multifaceted effects of antigen valency on B cell response composition and differentiation in vivo Y Kato, RK Abbott, BL Freeman, S Haupt, B Groschel, M Silva, S Menis, ... Immunity 53 (3), 548-563. e8, 2020 | 177 | 2020 |
Germinal center hypoxia potentiates immunoglobulin class switch recombination RK Abbott, M Thayer, J Labuda, M Silva, P Philbrook, DW Cain, H Kojima, ... The Journal of Immunology 197 (10), 4014-4020, 2016 | 116 | 2016 |
Increased peripheral blood neutrophil activation phenotypes and neutrophil extracellular trap formation in critically ill coronavirus disease 2019 (COVID-19) patients: a case … JA Masso-Silva, A Moshensky, MTY Lam, MF Odish, A Patel, L Xu, ... Clinical Infectious Diseases 74 (3), 479-489, 2022 | 92 | 2022 |
Factors in B cell competition and immunodominance RK Abbott, S Crotty Immunological reviews 296 (1), 120-131, 2020 | 74 | 2020 |
When designing vaccines, consider the starting material: the human B cell repertoire C Havenar-Daughton, RK Abbott, WR Schief, S Crotty Current opinion in immunology 53, 209-216, 2018 | 64 | 2018 |
B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models D Huang, RK Abbott, C Havenar-Daughton, PD Skog, R Al-Kolla, ... Proceedings of the National Academy of Sciences 117 (37), 22920-22931, 2020 | 56 | 2020 |
Increased peripheral blood neutrophil activation phenotypes and NETosis in critically ill COVID-19 patients JA Masso-Silva, A Moshensky, MTY Lam, M Odish, A Patel, L Xu, ... medRxiv, 2021.01. 14.21249831, 2021 | 40 | 2021 |
The GS protein-coupled A2a adenosine receptor controls T cell help in the germinal center RK Abbott, M Silva, J Labuda, M Thayer, DW Cain, P Philbrook, ... Journal of Biological Chemistry 292 (4), 1211-1217, 2017 | 28 | 2017 |
Targeted elimination of immunodominant B cells drives the germinal center reaction toward subdominant epitopes M Silva, TH Nguyen, P Philbrook, M Chu, O Sears, S Hatfield, RK Abbott, ... Cell reports 21 (13), 3672-3680, 2017 | 25 | 2017 |
Highly mutated antibodies capable of neutralizing N276 glycan-deficient HIV after a single immunization with an Env trimer JH Lee, C Nakao, M Appel, A Le, E Landais, O Kalyuzhniy, X Hu, ... Cell Reports 38 (10), 2022 | 8 | 2022 |
Dynamic activity in cis-regulatory elements of leukocytes identifies transcription factor activation and stratifies COVID-19 severity in ICU patients MTY Lam, SH Duttke, MF Odish, HD Le, EA Hansen, CT Nguyen, ... Cell Reports Medicine 4 (2), 2023 | 6 | 2023 |
Profiling transcription initiation in peripheral leukocytes reveals severity-associated cis-regulatory elements in critical COVID-19 MTY Lam, SH Duttke, MF Odish, HD Le, EA Hansen, CT Nguyen, ... BioRxiv, 2021 | 6 | 2021 |
Increased IL-8, neutrophil activation phenotypes and NETosis in critically ill COVID-19 patients JA Masso-Silva, A Moshensky, MTY Lam, M Odish, A Patel, L Xu, ... | 3 | 2020 |