Autoantibodies against type I IFNs in patients with life-threatening COVID-19 P Bastard, LB Rosen, Q Zhang, E Michailidis, HH Hoffmann, Y Zhang, ... Science 370 (6515), eabd4585, 2020 | 2098 | 2020 |
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 Q Zhang, P Bastard, Z Liu, J Le Pen, M Moncada-Velez, J Chen, M Ogishi, ... Science 370 (6515), eabd4570, 2020 | 1808 | 2020 |
Variation in the human immune system is largely driven by non-heritable influences P Brodin, V Jojic, T Gao, S Bhattacharya, CJL Angel, D Furman, ... Cell 160 (1-2), 37-47, 2015 | 931 | 2015 |
The immunology of multisystem inflammatory syndrome in children with COVID-19 CR Consiglio, N Cotugno, F Sardh, C Pou, D Amodio, L Rodriguez, Z Tan, ... Cell 183 (4), 968-981. e7, 2020 | 765 | 2020 |
Immune determinants of COVID-19 disease presentation and severity P Brodin Nature medicine 27 (1), 28-33, 2021 | 555 | 2021 |
Human immune system variation P Brodin, MM Davis Nature reviews immunology 17 (1), 21-29, 2017 | 550 | 2017 |
Stereotypic immune system development in newborn children A Olin, E Henckel, Y Chen, T Lakshmikanth, C Pou, J Mikes, A Gustafsson, ... Cell 174 (5), 1277-1292. e14, 2018 | 483 | 2018 |
Why is COVID‐19 so mild in children? P Brodin Acta Paediatrica 109 (6), 1082-1083, 2020 | 453 | 2020 |
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ... Science immunology 6 (62), eabl4340, 2021 | 323 | 2021 |
The strength of inhibitory input during education quantitatively tunes the functional responsiveness of individual natural killer cells P Brodin, T Lakshmikanth, S Johansson, K Kärre, P Höglund Blood, The Journal of the American Society of Hematology 113 (11), 2434-2441, 2009 | 320 | 2009 |
NK cell education: not an on-off switch but a tunable rheostat P Brodin, K Kärre, P Höglund Trends in immunology 30 (4), 143-149, 2009 | 319 | 2009 |
Current perspectives of natural killer cell education by MHC class I molecules P Höglund, P Brodin Nature reviews immunology 10 (10), 724-734, 2010 | 304 | 2010 |
A genome-wide transcriptomic analysis of protein-coding genes in human blood cells M Uhlen, MJ Karlsson, W Zhong, A Tebani, C Pou, J Mikes, ... Science 366 (6472), eaax9198, 2019 | 293 | 2019 |
Treatment of multisystem inflammatory syndrome in children AJ McArdle, O Vito, H Patel, EG Seaby, P Shah, C Wilson, C Broderick, ... New England Journal of Medicine 385 (1), 11-22, 2021 | 286 | 2021 |
Bifidobacteria-mediated immune system imprinting early in life BM Henrick, L Rodriguez, T Lakshmikanth, C Pou, E Henckel, ... Cell 184 (15), 3884-3898. e11, 2021 | 254 | 2021 |
X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19 T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ... Science immunology 6 (62), eabl4348, 2021 | 243 | 2021 |
Automatic classification of cellular expression by nonlinear stochastic embedding (ACCENSE) K Shekhar, P Brodin, MM Davis, AK Chakraborty Proceedings of the National Academy of Sciences 111 (1), 202-207, 2014 | 232 | 2014 |
MiR-125b, a microRNA downregulated in psoriasis, modulates keratinocyte proliferation by targeting FGFR2 N Xu, P Brodin, T Wei, F Meisgen, L Eidsmo, N Nagy, L Kemeny, M Ståhle, ... Journal of Investigative Dermatology 131 (7), 1521-1529, 2011 | 232 | 2011 |
A global effort to define the human genetics of protective immunity to SARS-CoV-2 infection JL Casanova, HC Su, L Abel, A Aiuti, S Almuhsen, AA Arias, P Bastard, ... Cell 181 (6), 1194-1199, 2020 | 213 | 2020 |
Systems-level immunomonitoring from acute to recovery phase of severe COVID-19 L Rodriguez, PT Pekkarinen, T Lakshmikanth, Z Tan, CR Consiglio, ... Cell Reports Medicine 1 (5), 100078, 2020 | 178 | 2020 |