Handling heme: The mechanisms underlying the movement of heme within and between cells RK Donegan, CM Moore, DA Hanna, AR Reddi Free Radical Biology and Medicine 133, 88-100, 2019 | 133 | 2019 |
Structural basis for misfolding in myocilin-associated glaucoma RK Donegan, SE Hill, DM Freeman, E Nguyen, SD Orwig, KC Turnage, ... Human molecular genetics 24 (8), 2111-2124, 2015 | 78 | 2015 |
Discovery of molecular therapeutics for glaucoma: challenges, successes, and promising directions: miniperspective RK Donegan, RL Lieberman Journal of medicinal chemistry 59 (3), 788-809, 2016 | 58 | 2016 |
A blueprint for academic laboratories to produce SARS-CoV-2 quantitative RT-PCR test kits SJ Mascuch, S Fakhretaha-Aval, JC Bowman, MTH Ma, G Thomas, ... Journal of Biological Chemistry 295 (46), 15438-15453, 2020 | 37 | 2020 |
The glaucoma-associated olfactomedin domain of myocilin forms polymorphic fibrils that are constrained by partial unfolding and peptide sequence SE Hill, RK Donegan, RL Lieberman Journal of molecular biology 426 (4), 921-935, 2014 | 37 | 2014 |
The glaucoma-associated olfactomedin domain of myocilin is a novel calcium binding protein RK Donegan, SE Hill, KC Turnage, SD Orwig, RL Lieberman Journal of Biological Chemistry 287 (52), 43370-43377, 2012 | 37 | 2012 |
Heme and hemoglobin suppress amyloid β–mediated inflammatory activation of mouse astrocytes LBW Sitara B. Sankar, Rebecca K. Donegan, Kajol J. Shah, Amit R. Reddi Journal of Biological Chemistry 293 (11358), 2018 | 35 | 2018 |
Structure and misfolding of the flexible tripartite coiled-coil domain of glaucoma-associated myocilin SE Hill, E Nguyen, RK Donegan, AC Patterson-Orazem, A Hazel, ... Structure 25 (11), 1697-1707. e5, 2017 | 27 | 2017 |
Using genetically encoded heme sensors to probe the mechanisms of heme uptake and homeostasis in Candida albicans Z Weissman, M Pinsky, RK Donegan, AR Reddi, D Kornitzer Cellular microbiology 23 (2), e13282, 2021 | 18 | 2021 |
Molecular details of olfactomedin domains provide pathway to structure-function studies SE Hill, RK Donegan, E Nguyen, TM Desai, RL Lieberman PloS one 10 (6), e0130888, 2015 | 18 | 2015 |
The role of host heme in bacterial infection RK Donegan Biological Chemistry 403 (11-12), 1017-1029, 2022 | 8 | 2022 |
Exogenously scavenged and endogenously synthesized heme are differentially utilized by Mycobacterium tuberculosis RK Donegan, Y Fu, J Copeland, S Idga, G Brown, OF Hale, A Mitra, ... Microbiology Spectrum 10 (5), e03604-22, 2022 | 6 | 2022 |
New direction for glaucoma therapeutics: focus on the olfactomedin domain of myocilin RK Donegan, RL Lieberman Future Medicinal Chemistry 4 (17), 2131-2134, 2012 | 3 | 2012 |
Regulation of heme biosynthesis via the coproporphyrin dependent pathway in bacteria H Aftab, RK Donegan Frontiers in Microbiology 15, 1345389, 2024 | 2 | 2024 |
Fluorometric Methods to Measure Bioavailable and Total Heme IM Dominic, MM Willoughby, AK Freer, CM Moore, RK Donegan, ... Iron Metabolism: Methods and Protocols, 151-194, 2024 | | 2024 |
The terminal heme synthetic enzyme, Coproheme Decarboxylase, coordinates heme synthesis and uptake in response to iron in Mycobacteria RK Donegan, J Copeland, S Edgha, G Brown, OF Hale, A Mitra, H Yang, ... bioRxiv, 2021.05. 10.443464, 2021 | | 2021 |
Molecular architecture of myocilin and structural defects imparted by non-synonymous mutations in its coiled coil domain RL Lieberman, SE Hill, E Nguyen, RK Donegan Investigative Ophthalmology & Visual Science 58 (8), 4906-4906, 2017 | | 2017 |
Molecular structures of olfactomedin domains from different subfamilies RL Lieberman, S Hill, RK Donegan, E Nguyen Investigative Ophthalmology & Visual Science 56 (7), 5525-5525, 2015 | | 2015 |
Structural and biophysical characterization of the myocilin olfactomedin domain RK Donegan Georgia Institute of Technology, 2015 | | 2015 |
Crystal structure of the olfactomedin domain of myocilin RL Lieberman, R Donegan Investigative Ophthalmology & Visual Science 55 (13), 5031-5031, 2014 | | 2014 |