Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl-and butyryl-cholinesterase F Nachon, E Carletti, C Ronco, M Trovaslet, Y Nicolet, L Jean, PY Renard Biochemical Journal 453 (3), 393-399, 2013 | 403 | 2013 |
Compounds triggering ER stress exert anti-melanoma effects and overcome BRAF inhibitor resistance M Cerezo, A Lehraiki, A Millet, F Rouaud, M Plaisant, E Jaune, T Botton, ... Cancer cell 29 (6), 805-819, 2016 | 242 | 2016 |
Metastatic melanoma: insights into the evolution of the treatments and future challenges A Millet, AR Martin, C Ronco, S Rocchi, R Benhida Medicinal research reviews 37 (1), 98-148, 2017 | 114 | 2017 |
Human butyrylcholinesterase produced in insect cells: huprine‐based affinity purification and crystal structure X Brazzolotto, M Wandhammer, C Ronco, M Trovaslet, L Jean, ... The FEBS journal 279 (16), 2905-2916, 2012 | 112 | 2012 |
ATM, ATR, CHK1, CHK2 and WEE1 inhibitors in cancer and cancer stem cells C Ronco, AR Martin, L Demange, R Benhida Medchemcomm 8 (2), 295-319, 2017 | 105 | 2017 |
Synthesis and structure–activity relationship of Huprine derivatives as human acetylcholinesterase inhibitors C Ronco, G Sorin, F Nachon, R Foucault, L Jean, A Romieu, PY Renard Bioorganic & medicinal chemistry 17 (13), 4523-4536, 2009 | 58 | 2009 |
Synthesis and biological evaluation of 3-amino-1, 2, 4-triazole derivatives as potential anticancer compounds O Grytsai, O Valiashko, M Penco-Campillo, M Dufies, A Hagege, ... Bioorganic chemistry 104, 104271, 2020 | 57 | 2020 |
Controlling plasma stability of hydroxamic acids: A medchem toolbox P Hermant, D Bosc, C Piveteau, R Gealageas, B Lam, C Ronco, ... Journal of Medicinal Chemistry 60 (21), 9067-9089, 2017 | 51 | 2017 |
New CXCR1/CXCR2 inhibitors represent an effective treatment for kidney or head and neck cancers sensitive or refractory to reference treatments M Dufies, O Grytsai, C Ronco, O Camara, D Ambrosetti, A Hagege, ... Theranostics 9 (18), 5332, 2019 | 44 | 2019 |
New huprine derivatives functionalized at position 9 as highly potent acetylcholinesterase inhibitors C Ronco, R Foucault, E Gillon, P Bohn, F Nachon, L Jean, PY Renard ChemMedChem 6 (5), 876-888, 2011 | 44 | 2011 |
A fluorescent immunochromatographic test using immunoliposomes for detecting microcystins and nodularins N Khreich, P Lamourette, B Lagoutte, C Ronco, X Franck, C Créminon, ... Analytical and bioanalytical chemistry 397 (5), 1733-1742, 2010 | 44 | 2010 |
Huprine derivatives as sub‐nanomolar human acetylcholinesterase inhibitors: from rational design to validation by X‐ray crystallography C Ronco, E Carletti, JP Colletier, M Weik, F Nachon, L Jean, PY Renard ChemMedChem 7 (3), 400-405, 2012 | 39 | 2012 |
The GRP78/BiP inhibitor HA15 synergizes with mitotane action against adrenocortical carcinoma cells through convergent activation of ER stress pathways C Ruggiero, M Doghman-Bouguerra, C Ronco, R Benhida, S Rocchi, ... Molecular and cellular endocrinology 474, 57-64, 2018 | 36 | 2018 |
Structure–activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino] acetic acids, dual binders of human insulin-degrading enzyme J Charton, M Gauriot, J Totobenazara, N Hennuyer, J Dumont, D Bosc, ... European journal of medicinal chemistry 90, 547-567, 2015 | 31 | 2015 |
Recent advances in age-related macular degeneration therapies M Fabre, L Mateo, D Lamaa, S Baillif, G Pagès, L Demange, C Ronco, ... Molecules 27 (16), 5089, 2022 | 28 | 2022 |
Discovery and Optimization of N-(4-(3-Aminophenyl)thiazol-2-yl)acetamide as a Novel Scaffold Active against Sensitive and Resistant Cancer Cells A Millet, M Plaisant, C Ronco, M Cerezo, P Abbe, E Jaune, E Cavazza, ... Journal of medicinal chemistry 59 (18), 8276-8292, 2016 | 27 | 2016 |
Reaction site-driven regioselective synthesis of AChE inhibitors E Oueis, G Santoni, C Ronco, O Syzgantseva, V Tognetti, L Joubert, ... Organic & biomolecular chemistry 12 (1), 156-161, 2014 | 26 | 2014 |
Improved synthetic pathway for the derivatization of huprine scaffold C Ronco, L Jean, PY Renard Tetrahedron 66 (37), 7399-7404, 2010 | 26 | 2010 |
Unified Azoline and Azole Syntheses by Optimized Aza‐Wittig Chemistry P Loos, C Ronco, M Riedrich, HD Arndt European Journal of Organic Chemistry 2013 (16), 3290-3315, 2013 | 25 | 2013 |
Hypoxia inducible factor down-regulation, cancer and cancer stem cells (CSCs): ongoing success stories AR Martin, C Ronco, L Demange, R Benhida MedChemComm 8 (1), 21-52, 2017 | 22 | 2017 |