| Selfish genes, the phenotype paradigm and genome evolution WF Doolittle, C Sapienza Nature 284 (5757), 601-603, 1980 | 2356 | 1980 |
| Phylogenetic classification and the universal tree WF Doolittle Science 284 (5423), 2124-2128, 1999 | 2345 | 1999 |
| A kingdom-level phylogeny of eukaryotes based on combined protein data SL Baldauf, AJ Roger, I Wenk-Siefert, WF Doolittle Science 290 (5493), 972-977, 2000 | 1492 | 2000 |
| Prokaryotic evolution in light of gene transfer JP Gogarten, WF Doolittle, JG Lawrence Molecular biology and evolution 19 (12), 2226-2238, 2002 | 1144 | 2002 |
| The complete genome of the crenarchaeon Sulfolobus solfataricus P2 Q She, RK Singh, F Confalonieri, Y Zivanovic, G Allard, MJ Awayez, ... Proceedings of the National Academy of Sciences 98 (14), 7835-7840, 2001 | 964 | 2001 |
| Use of 16S rRNA and rpoB Genes as Molecular Markers for Microbial Ecology Studies RJ Case, Y Boucher, I Dahllöf, C Holmström, WF Doolittle, ... Applied and environmental microbiology 73 (1), 278-288, 2007 | 895 | 2007 |
| Has the endosymbiont hypothesis been proven? MW Gray, WF Doolittle Microbiological Reviews 46 (1), 1-42, 1982 | 719 | 1982 |
| You are what you eat: a gene transfer ratchet could account for bacterial genes in eukaryotic nuclear genomes WF Doolittle Trends in Genetics 14 (8), 307-311, 1998 | 676 | 1998 |
| Archaea and the prokaryote-to-eukaryote transition JR Brown, WF Doolittle Microbiology and Molecular Biology Reviews 61 (4), 456-502, 1997 | 674 | 1997 |
| Differences between tissue-associated intestinal microfloras of patients with Crohn's disease and ulcerative colitis U Gophna, K Sommerfeld, S Gophna, WF Doolittle, ... Journal of clinical microbiology 44 (11), 4136-4141, 2006 | 651 | 2006 |
| Microsporidia are related to Fungi: evidence from the largest subunit of RNA polymerase II and other proteins RP Hirt, JM Logsdon Jr, B Healy, MW Dorey, WF Doolittle, TM Embley Proceedings of the National Academy of Sciences 96 (2), 580-585, 1999 | 645 | 1999 |
| Genes in pieces: were they ever together? WF Doolittle Nature 272 (5654), 581-582, 1978 | 599 | 1978 |
| Comparison of Bayesian and maximum likelihood bootstrap measures of phylogenetic reliability CJ Douady, F Delsuc, Y Boucher, WF Doolittle, EJP Douzery Molecular biology and evolution 20 (2), 248-254, 2003 | 573 | 2003 |
| Pattern pluralism and the Tree of Life hypothesis WF Doolittle, E Bapteste Proceedings of the National Academy of Sciences 104 (7), 2043-2049, 2007 | 564 | 2007 |
| Lateral gene transfer and the origins of prokaryotic groups Y Boucher, CJ Douady, RT Papke, DA Walsh, MER Boudreau, CL Nesbø, ... Annual review of genetics 37 (1), 283-328, 2003 | 516 | 2003 |
| The new science of metagenomics: revealing the secrets of our microbial planet National Research Council, Division on Earth, Life Studies, ... National Academies Press, 2007 | 510* | 2007 |
| Lateral genomics WF Doolittle Trends in Biochemical Sciences 24 (12), M5-M8, 1999 | 510 | 1999 |
| Root of the universal tree of life based on ancient aminoacyl-tRNA synthetase gene duplications. JR Brown, WF Doolittle Proceedings of the National Academy of Sciences 92 (7), 2441-2445, 1995 | 490 | 1995 |
| Is junk DNA bunk? A critique of ENCODE WF Doolittle Proceedings of the National Academy of Sciences 110 (14), 5294-5300, 2013 | 481 | 2013 |
| Origin and evolution of the slime molds (Mycetozoa) SL Baldauf, WF Doolittle Proceedings of the National Academy of Sciences 94 (22), 12007-12012, 1997 | 455 | 1997 |
