| Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation RM Chemelli, JT Willie, CM Sinton, JK Elmquist, T Scammell, C Lee, ... Cell 98 (4), 437-451, 1999 | 3627 | 1999 |
| Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. S Ishibashi, MS Brown, JL Goldstein, RD Gerard, RE Hammer, J Herz The Journal of clinical investigation 92 (2), 883-893, 1993 | 2028 | 1993 |
| Dramatic growth of mice that develop from eggs microinjected with metallothionein–growth hormone fusion genes RD Palmiter, RL Brinster, RE Hammer, ME Trumbauer, MG Rosenfeld, ... Nature 300 (5893), 611-615, 1982 | 2017 | 1982 |
| Synaptotagmin I: a major Ca2+ sensor for transmitter release at a central synapse M Geppert, Y Goda, RE Hammer, C Li, TW Rosahl, CF Stevens, ... Cell 79 (4), 717-727, 1994 | 1827 | 1994 |
| Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXRα DJ Peet, SD Turley, W Ma, BA Janowski, JMA Lobaccaro, RE Hammer, ... Cell 93 (5), 693-704, 1998 | 1814 | 1998 |
| Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41 BS Samuel, A Shaito, T Motoike, FE Rey, F Backhed, JK Manchester, ... Proceedings of the National Academy of Sciences 105 (43), 16767-16772, 2008 | 1806 | 2008 |
| Endocrine regulation of the fasting response by PPARα-mediated induction of fibroblast growth factor 21 T Inagaki, P Dutchak, G Zhao, X Ding, L Gautron, V Parameswara, Y Li, ... Cell metabolism 5 (6), 415-425, 2007 | 1723 | 2007 |
| Production of transgenic rabbits, sheep and pigs by microinjection RE Hammer, VG Pursel, CE Rexroad Jr, RJ Wall, DJ Bolt, KM Ebert, ... Nature 315 (6021), 680-683, 1985 | 1617 | 1985 |
| Synaptic assembly of the brain in the absence of neurotransmitter secretion M Verhage, AS Maia, JJ Plomp, AB Brussaard, JH Heeroma, H Vermeer, ... Science 287 (5454), 864-869, 2000 | 1536 | 2000 |
| Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2 M Trommsdorff, M Gotthardt, T Hiesberger, J Shelton, W Stockinger, ... Cell 97 (6), 689-701, 1999 | 1487 | 1999 |
| The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats. JD Taurog, JA Richardson, JT Croft, WA Simmons, M Zhou, ... The Journal of experimental medicine 180 (6), 2359-2364, 1994 | 1387 | 1994 |
| Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo YY Kisanuki, RE Hammer, J Miyazaki, SC Williams, JA Richardson, ... Developmental biology 230 (2), 230-242, 2001 | 1384 | 2001 |
| Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy I Shimomura, RE Hammer, S Ikemoto, MS Brown, JL Goldstein Nature 401 (6748), 73-76, 1999 | 1317 | 1999 |
| White fat progenitor cells reside in the adipose vasculature W Tang, D Zeve, JM Suh, D Bosnakovski, M Kyba, RE Hammer, ... Science 322 (5901), 583-586, 2008 | 1285 | 2008 |
| Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human β2m: an animal model of HLA-B27-associated human disorders RE Hammer, SD Maika, JA Richardson, JP Tang, JD Taurog Cell 63 (5), 1099-1112, 1990 | 1273 | 1990 |
| Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice K Hosoda, RE Hammer, JA Richardson, AG Baynash, JC Cheung, ... Cell 79 (7), 1267-1276, 1994 | 1191 | 1994 |
| A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice K Tabuchi, J Blundell, MR Etherton, RE Hammer, X Liu, CM Powell, ... science 318 (5847), 71-76, 2007 | 1181 | 2007 |
| Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons AG Baynash, K Hosoda, A Giaid, JA Richardson, N Emoto, RE Hammer, ... Cell 79 (7), 1277-1285, 1994 | 1147 | 1994 |
| Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice I Shimomura, M Matsuda, RE Hammer, Y Bashmakov, MS Brown, ... Molecular cell 6 (1), 77-86, 2000 | 1062 | 2000 |
| Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy I Shimomura, RE Hammer, JA Richardson, S Ikemoto, Y Bashmakov, ... Genes & development 12 (20), 3182-3194, 1998 | 1009 | 1998 |
