Machine learning-based reclassification of germline variants of unknown significance: The RENOVO algorithm V Favalli, G Tini, E Bonetti, G Vozza, A Guida, S Gandini, PG Pelicci, ... The American Journal of Human Genetics 108 (4), 682-695, 2021 | 36 | 2021 |
HDAC inhibition as potential therapeutic strategy to restore the deregulated immune response in severe COVID-19 C Ripamonti, V Spadotto, P Pozzi, A Stevenazzi, B Vergani, M Marchini, ... Frontiers in immunology 13, 841716, 2022 | 31 | 2022 |
Laniakea@ ReCaS: exploring the potential of customisable Galaxy on-demand instances as a cloud-based service MA Tangaro, P Mandreoli, M Chiara, G Donvito, M Antonacci, A Parisi, ... BMC bioinformatics 22, 1-21, 2021 | 8 | 2021 |
High-fat diet promotes Acute Promyelocytic Leukemia through PPARδ-enhanced self-renewal of preleukemic progenitors L Mazzarella, P Falvo, M Adinolfi, G Tini, E Gatti, R Piccioni, E Bonetti, ... Cancer Prevention Research 17 (2), 59-75, 2024 | 4 | 2024 |
Inhibition of the lysine demethylase LSD1 modulates the balance between inflammatory and antiviral responses against coronaviruses L Mazzarella, F Santoro, R Ravasio, V Fumagalli, PE Massa, ... Science Signaling 16 (816), eade0326, 2023 | 2 | 2023 |
Abstract P5-13-04: NF1 mutations render HER2+ breast cancer highly sensitive to T-DM1 by altering microtubule dynamics BA Duso, EG Dorronzoro, G Tini, MR de Filippo, E Bonetti, MR Ippolito, ... Cancer Research 82 (4_Supplement), P5-13-04-P5-13-04, 2022 | 1 | 2022 |
Inhibiting LSD1 suppresses coronavirus-induced inflammation but spares innate antiviral activity L Mazzarella, F Santoro, R Ravasio, PE Massa, S Rodighiero, E Gavilán, ... bioRxiv, 2021.05. 02.441948, 2021 | 1 | 2021 |
RENOVO-NF1 accurately predicts NF1 missense variant pathogenicity E Bonetti, S Pellegatta, N Rosati, M Eoli, L Mazzarella medRxiv, 2025.01. 06.25320039, 2025 | | 2025 |
Accuracy of renovo predictions on variants reclassified over time E Bonetti, G Tini, L Mazzarella Journal of Translational Medicine 22 (1), 713, 2024 | | 2024 |
Accuracy of RENOVO Predictions on Genetic Variants Reclassified Over Time E Bonetti, G Tini, L Mazzarella | | 2024 |
Abstract A013: NF1 loss is syntetic lethal with Trastuzumab emtansine E Messuti, BA Duso, A Castiglioni, G Tini, E Bonetti, G Ciossani, ... Molecular Cancer Therapeutics 23 (6_Supplement), A013-A013, 2024 | | 2024 |
Intra-tubular damage is targeted by maytansinoids and rescued by NF1: Revisiting mechanism and biomarkers of an established ADC payload E Messuti, BA Duso, A Castiglioni, G Tini, E Bonetti, G Ciossani, ... Cancer Research 84 (6_Supplement), 513-513, 2024 | | 2024 |
A novel, RAS-independent role for NF1 in microtubular dynamics and damage repair dictates sensitivity to T-DM1 in HER2-positive breast cancer BA Duso, E Messuti, G Tini, E Bonetti, A Castiglioni, G Frigè, G Ciossani, ... bioRxiv, 2023.12. 06.569572, 2023 | | 2023 |
A novel, RAS-independent role for NF1 in microtubular dynamics and damage repair dictates sensitivity to T-DM1 in HER2-positive breast cancer E Messuti, G Tini, E Bonetti, A Castiglioni, G Frige, G Ciossani, S Monzani, ... | | 2023 |
Benchmarking and improving the performance of variant-calling pipelines with RecallME G Vozza, E Bonetti, G Tini, V Favalli, G Frigè, G Bucci, S De Summa, ... Bioinformatics 39 (12), btad722, 2023 | | 2023 |
NF1 (neurofibromatosis 1) controls microtubule dynamics and dictates sensitivity to maytansinoids BA Duso, E Messuti, E Bonetti, G Tini, A Castiglioni, G Ciossani, ... Cancer Research 83 (7_Supplement), 4896-4896, 2023 | | 2023 |
Computer-Assisted Interpretation of Cancer-Predisposing Variants E Bonetti, G Vozza, L Mazzarella Hereditary Gastric and Breast Cancer Syndrome: CDH1: One Genotype with …, 2023 | | 2023 |