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Emanuele Bonetti
Emanuele Bonetti
Post Doc Fellow European Institute of Oncology
在 ieo.it 的电子邮件经过验证
标题
引用次数
引用次数
年份
Machine learning-based reclassification of germline variants of unknown significance: The RENOVO algorithm
V Favalli, G Tini, E Bonetti, G Vozza, A Guida, S Gandini, PG Pelicci, ...
The American Journal of Human Genetics 108 (4), 682-695, 2021
362021
HDAC inhibition as potential therapeutic strategy to restore the deregulated immune response in severe COVID-19
C Ripamonti, V Spadotto, P Pozzi, A Stevenazzi, B Vergani, M Marchini, ...
Frontiers in immunology 13, 841716, 2022
312022
Laniakea@ ReCaS: exploring the potential of customisable Galaxy on-demand instances as a cloud-based service
MA Tangaro, P Mandreoli, M Chiara, G Donvito, M Antonacci, A Parisi, ...
BMC bioinformatics 22, 1-21, 2021
82021
High-fat diet promotes Acute Promyelocytic Leukemia through PPARδ-enhanced self-renewal of preleukemic progenitors
L Mazzarella, P Falvo, M Adinolfi, G Tini, E Gatti, R Piccioni, E Bonetti, ...
Cancer Prevention Research 17 (2), 59-75, 2024
42024
Inhibition of the lysine demethylase LSD1 modulates the balance between inflammatory and antiviral responses against coronaviruses
L Mazzarella, F Santoro, R Ravasio, V Fumagalli, PE Massa, ...
Science Signaling 16 (816), eade0326, 2023
22023
Abstract P5-13-04: NF1 mutations render HER2+ breast cancer highly sensitive to T-DM1 by altering microtubule dynamics
BA Duso, EG Dorronzoro, G Tini, MR de Filippo, E Bonetti, MR Ippolito, ...
Cancer Research 82 (4_Supplement), P5-13-04-P5-13-04, 2022
12022
Inhibiting LSD1 suppresses coronavirus-induced inflammation but spares innate antiviral activity
L Mazzarella, F Santoro, R Ravasio, PE Massa, S Rodighiero, E Gavilán, ...
bioRxiv, 2021.05. 02.441948, 2021
12021
RENOVO-NF1 accurately predicts NF1 missense variant pathogenicity
E Bonetti, S Pellegatta, N Rosati, M Eoli, L Mazzarella
medRxiv, 2025.01. 06.25320039, 2025
2025
Accuracy of renovo predictions on variants reclassified over time
E Bonetti, G Tini, L Mazzarella
Journal of Translational Medicine 22 (1), 713, 2024
2024
Accuracy of RENOVO Predictions on Genetic Variants Reclassified Over Time
E Bonetti, G Tini, L Mazzarella
2024
Abstract A013: NF1 loss is syntetic lethal with Trastuzumab emtansine
E Messuti, BA Duso, A Castiglioni, G Tini, E Bonetti, G Ciossani, ...
Molecular Cancer Therapeutics 23 (6_Supplement), A013-A013, 2024
2024
Intra-tubular damage is targeted by maytansinoids and rescued by NF1: Revisiting mechanism and biomarkers of an established ADC payload
E Messuti, BA Duso, A Castiglioni, G Tini, E Bonetti, G Ciossani, ...
Cancer Research 84 (6_Supplement), 513-513, 2024
2024
A novel, RAS-independent role for NF1 in microtubular dynamics and damage repair dictates sensitivity to T-DM1 in HER2-positive breast cancer
BA Duso, E Messuti, G Tini, E Bonetti, A Castiglioni, G Frigè, G Ciossani, ...
bioRxiv, 2023.12. 06.569572, 2023
2023
A novel, RAS-independent role for NF1 in microtubular dynamics and damage repair dictates sensitivity to T-DM1 in HER2-positive breast cancer
E Messuti, G Tini, E Bonetti, A Castiglioni, G Frige, G Ciossani, S Monzani, ...
2023
Benchmarking and improving the performance of variant-calling pipelines with RecallME
G Vozza, E Bonetti, G Tini, V Favalli, G Frigè, G Bucci, S De Summa, ...
Bioinformatics 39 (12), btad722, 2023
2023
NF1 (neurofibromatosis 1) controls microtubule dynamics and dictates sensitivity to maytansinoids
BA Duso, E Messuti, E Bonetti, G Tini, A Castiglioni, G Ciossani, ...
Cancer Research 83 (7_Supplement), 4896-4896, 2023
2023
Computer-Assisted Interpretation of Cancer-Predisposing Variants
E Bonetti, G Vozza, L Mazzarella
Hereditary Gastric and Breast Cancer Syndrome: CDH1: One Genotype with …, 2023
2023
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