Rapid neuronal differentiation of induced pluripotent stem cells for measuring network activity on micro-electrode arrays M Frega, SHC Van Gestel, K Linda, J Van Der Raadt, J Keller, ... JoVE (Journal of Visualized Experiments), e54900, 2017 | 158 | 2017 |
Neuronal network dysfunction in a model for Kleefstra syndrome mediated by enhanced NMDAR signaling M Frega, K Linda, JM Keller, G Gümüş-Akay, B Mossink, JR van Rhijn, ... Nature communications 10 (1), 4928, 2019 | 128 | 2019 |
Ptchd1 deficiency induces excitatory synaptic and cognitive dysfunctions in mouse DC Ung, G Iacono, H Méziane, E Blanchard, MA Papon, M Selten, ... Molecular psychiatry 23 (5), 1356-1367, 2018 | 86 | 2018 |
Cadherin-13 is a critical regulator of GABAergic modulation in human stem-cell-derived neuronal networks B Mossink, JR Van Rhijn, S Wang, K Linda, MR Vitale, JEM Zöller, ... Molecular Psychiatry 27 (1), 1-18, 2022 | 66 | 2022 |
Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway S Wang, JR van Rhijn, I Akkouh, N Kogo, N Maas, A Bleeck, IS Ortiz, ... Cell reports 39 (5), 2022 | 35 | 2022 |
Foxp2 loss of function increases striatal direct pathway inhibition via increased GABA release JR van Rhijn, SE Fisher, SC Vernes, N Nadif Kasri Brain Structure and Function 223, 4211-4226, 2018 | 27 | 2018 |
SETD1A mediated H3K4 methylation and its role in neurodevelopmental and neuropsychiatric disorders S Wang, A Bleeck, N Nadif Kasri, T Kleefstra, JR van Rhijn, D Schubert Frontiers in Molecular Neuroscience 14, 772000, 2021 | 20 | 2021 |
Brunner syndrome associated MAOA mutations result in NMDAR hyperfunction and increased network activity in human dopaminergic neurons JR Van Rhijn, Y Shi, M Bormann, B Mossink, M Frega, H Recaioglu, ... Neurobiology of disease 163, 105587, 2022 | 10 | 2022 |
Retinoic acid signaling: A new piece in the spoken language puzzle JR Van Rhijn, SC Vernes Frontiers in Psychology 6, 1816, 2015 | 9 | 2015 |
Neuronal network dysfunction in a human model for Kleefstra syndrome mediated by enhanced NMDAR signaling M Frega, K Linda, JM Keller, G Gümüş-Akay, B Mossink, JR van Rhijn, ... bioRxiv, 585596, 2019 | 7 | 2019 |
Neuronal network dysfunction in a model for Kleefstra syndrome mediated by enhanced NMDAR signaling. Nat. Commun. 10, 1–15 M Frega, K Linda, JM Keller, G Gümüsç-Akay, B Mossink, JR van Rhijn, ... | 6 | 2019 |
A human in vitro neuronal model for studying homeostatic plasticity at the network level X Yuan, S Puvogel, JR van Rhijn, U Ciptasari, A Esteve-Codina, M Meijer, ... Stem cell reports 18 (11), 2222-2239, 2023 | 4 | 2023 |
Brunner Syndrome associated MAOA dysfunction in human induced dopaminergic neurons results in dysregulated NMDAR expression and increased network activity Y Shi, JR Van Rhijn, M Bormann, B Mossink, M Frega, M Hakobjan, ... bioRxiv, 741108, 2019 | 4 | 2019 |
Brunner syndrome associated MAOA dysfunction in human dopaminergic neurons results in NMDAR hyperfunction and increased network activity Y Shi, JR van Rhijn, M Bormann, B Mossink, M Frega, H Recaioglu, ... bioRxiv, 2020.10. 28.359224, 2020 | | 2020 |
The cell-type specific contribution of EHMT1 to E/I balance in human in vitro neuronal networks B Mossink, JR van Rhijn, AHA Verboven, G Parodi, S Wang, M Negwer, ... The cell-type specific contribution of EHMT1 to neuronal network dysfunction …, 2020 | | 2020 |
Cadherin 13 interacts with Integrin Beta-1 and Integrin Beta-3 to regulate inhibitory synaptic function in a human neuronal model B Mossink, J van Rhijn, M Selten, K Linda, E van Hughte, J Bak, M Frega, ... EUROPEAN JOURNAL OF HUMAN GENETICS 27, 1435-1435, 2019 | | 2019 |
van Rhijn, JR, Fisher, SE, Vernes, SC, and Nadif-Kasri, N.(2018). Foxp2 loss of function increases striatal direct pathway inhibition via increased GABA release. Submitted. JR van Rhijn FOXP2 IN, 201, 2019 | | 2019 |
Heterozygous DNA-binding domain mutation of Foxp2 impairs striatal inhibition JR van Rhijn, SE Fisher, SC Vernes, NN Kasri FOXP2 IN, 93, 2019 | | 2019 |
Reduced excitatory activity in a human dopaminergic model for FOXP2 homozygous deletion JR van Rhijn, Y Shi, M Frega, D Schubert, T Maricic, S Pääbo, NN Kasri FOXP2 IN, 133, 2019 | | 2019 |
The role of FoxP2 in striatal circuitry JR Van Rhijn Radboud University Nijmegen Nijmegen, 2019 | | 2019 |