CUG-binding protein 1 regulates HSC activation and liver fibrogenesis X Wu, X Wu, Y Ma, F Shao, Y Tan, T Tan, L Gu, Y Zhou, B Sun, Y Sun, ... Nature communications 7 (1), 13498, 2016 | 87 | 2016 |
Andrographolide alleviates imiquimod-induced psoriasis in mice via inducing autophagic proteolysis of MyD88 F Shao, T Tan, Y Tan, Y Sun, X Wu, Q Xu Biochemical Pharmacology 115, 94-103, 2016 | 54 | 2016 |
Role of CXCR3 signaling in response to anti-PD-1 therapy X Han, Y Wang, J Sun, T Tan, X Cai, P Lin, Y Tan, B Zheng, B Wang, ... EBioMedicine 48, 169-177, 2019 | 52 | 2019 |
Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells Z Wang, M Burigotto, S Ghetti, F Vaillant, T Tan, BD Capaldo, M Palmieri, ... Cancer Discovery 14 (2), 362-379, 2024 | 24 | 2024 |
Low-viscosity matrix suspension culture enables scalable analysis of patient-derived organoids and tumoroids from the large intestine Y Hirokawa, J Clarke, M Palmieri, T Tan, D Mouradov, S Li, C Lin, F Li, ... Communications biology 4 (1), 1067, 2021 | 23 | 2021 |
The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells Z Wang, H Hu, L Heitink, K Rogers, Y You, T Tan, CLW Suen, A Garnham, ... Cell Death & Differentiation 30 (4), 1033-1046, 2023 | 20 | 2023 |
Genotype-Tailored ERK/MAPK Pathway and HDAC Inhibition Rewires the Apoptotic Rheostat to Trigger Colorectal Cancer Cell Death LJ Jenkins, IY Luk, WD Fairlie, EF Lee, M Palmieri, KL Schoffer, T Tan, ... Molecular Cancer Therapeutics 22 (1), 52-62, 2023 | 12 | 2023 |
Unified framework for patient-derived, tumor-organoid-based predictive testing of standard-of-care therapies in metastatic colorectal cancer T Tan, D Mouradov, M Lee, G Gard, Y Hirokawa, S Li, C Lin, F Li, H Luo, ... Cell Reports Medicine 4 (12), 2023 | 10 | 2023 |
A fumigaclavine C isostere alleviates Th1-mediated experimental colitis via competing with IFN-γ for binding to IFN-γ receptor 1 Y Tan, X Wu, J Sun, W Guo, F Gong, F Shao, T Tan, Y Cao, B Zheng, Y Gu, ... Biochemical Pharmacology 123, 63-72, 2017 | 7 | 2017 |
Low-viscosity matrix suspension culture for human colorectal epithelial organoids and tumoroids T Tan, Y Hirokawa, J Clarke, A Sakthianandeswaren, OM Sieber Bio-protocol 12 (8), e4394-e4394, 2022 | 6 | 2022 |
BCL-XL inhibitors enhance the apoptotic efficacy of BRAF inhibitors in BRAFV600E colorectal cancer J Mariadason, L Jenkins, I Luk, F Chionh, T Tan, K Needham, N Vukelic, ... | 1 | 2023 |
BCL-XL inhibitors enhance the apoptotic efficacy of BRAF inhibitors in BRAFV600E colorectal cancer LJ Jenkins, IY Luk, F Chionh, T Tan, K Needham, J Ayton, CM Reehorst, ... Cell Death & Disease 15 (3), 183, 2024 | | 2024 |
Abstract C043: Discovery of new drug combinations for metastatic colorectal cancer EJ In, T Tan, D Mouradov, A Sakthianandeswaren, A Au, K Lowes, ... Molecular Cancer Therapeutics 22 (12_Supplement), C043-C043, 2023 | | 2023 |
FORECAST-1: Feasibility of organoid response assessment to define effective treatments for patients with colorectal cancer after failure of standard therapy. M Lee, G Gard, J Tie, NC Tebbutt, T Tan, A Jalali, B Lee, O Sieber, ... Journal of Clinical Oncology 40 (16_suppl), 3583-3583, 2022 | | 2022 |
FORECAST-1: Feasibility of organoid response assessment to define effective treatments for patients with colorectal cancer after failure of standard therapy. G Gard, M Lee, Y Hirokawa, J Tie, J Clarke, NC Tebbutt, T Tan, A Jalali, ... Journal of Clinical Oncology 39 (15_suppl), e15571-e15571, 2021 | | 2021 |
Dual MAPK and HDAC inhibition rewires the apoptotic rheostat to trigger colorectal cancer cell death LJ Jenkins, IY Luk, M Palmieri, WD Fairlie, EF Lee, KL Schoffer, T Tan, ... bioRxiv, 2021.02. 15.431252, 2021 | | 2021 |
Metastatic colorectal cancer cells harness nonsense-mediated mRNA decay for immune evasion X Wu, T Tan, Q Xu The Journal of Immunology 204 (1_Supplement), 242.17-242.17, 2020 | | 2020 |
Resistance to anti-PD-1 therapy is associated with the retention of CXCR3+ CD4+ CD8-T cells in blood X Han, T Tan, J Sun, X Chen, X Cai, P Lin, Y Tan, B Wang, Y Wang, ... Annals of Oncology 29, viii425-viii426, 2018 | | 2018 |