Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys JC Crispín, M Oukka, G Bayliss, RA Cohen, CA Van Beek, IE Stillman, ... The journal of immunology 181 (12), 8761-8766, 2008 | 917 | 2008 |
Pathogenesis of human systemic lupus erythematosus: recent advances JC Crispín, SNC Liossis, K Kis-Toth, LA Lieberman, VC Kyttaris, YT Juang, ... Trends in molecular medicine 16 (2), 47-57, 2010 | 501 | 2010 |
The role of IL-23/IL-17 axis in lupus nephritis Z Zhang, VC Kyttaris, GC Tsokos The Journal of Immunology 183 (5), 3160-3169, 2009 | 360 | 2009 |
T cells as therapeutic targets in SLE JC Crispín, VC Kyttaris, C Terhorst, GC Tsokos Nature Reviews Rheumatology 6 (6), 317-325, 2010 | 297 | 2010 |
Systemic lupus erythematosus serum IgG increases CREM binding to the IL-2 promoter and suppresses IL-2 production through CaMKIV YT Juang, Y Wang, EE Solomou, Y Li, C Mawrin, K Tenbrock, VC Kyttaris, ... The Journal of clinical investigation 115 (4), 996-1005, 2005 | 271 | 2005 |
Cutting edge: IL-23 receptor deficiency prevents the development of lupus nephritis in C57BL/6–lpr/lpr mice VC Kyttaris, Z Zhang, VK Kuchroo, M Oukka, GC Tsokos The Journal of Immunology 184 (9), 4605-4609, 2010 | 240 | 2010 |
Phosphorylated ERM is responsible for increased T cell polarization, adhesion, and migration in patients with systemic lupus erythematosus Y Li, T Harada, YT Juang, VC Kyttaris, Y Wang, M Zidanic, K Tung, ... The Journal of Immunology 178 (3), 1938-1947, 2007 | 207 | 2007 |
Stat3 promotes IL-10 expression in lupus T cells through trans-activation and chromatin remodeling CM Hedrich, T Rauen, SA Apostolidis, AP Grammatikos, ... Proceedings of the National Academy of Sciences 111 (37), 13457-13462, 2014 | 177 | 2014 |
Protein phosphatase 2A is a negative regulator of IL-2 production in patients with systemic lupus erythematosus CG Katsiari, VC Kyttaris, YT Juang, GC Tsokos The Journal of clinical investigation 115 (11), 3193-3204, 2005 | 174 | 2005 |
Differential expression and molecular associations of Syk in systemic lupus erythematosus T cells S Krishnan, YT Juang, B Chowdhury, A Magilavy, CU Fisher, H Nguyen, ... The Journal of Immunology 181 (11), 8145-8152, 2008 | 150 | 2008 |
Immune cells and cytokines in systemic lupus erythematosus: an update VC Kyttaris, YT Juang, GC Tsokos Current opinion in rheumatology 17 (5), 518-522, 2005 | 145 | 2005 |
Increased expression of STAT3 in SLE T cells contributes to enhanced chemokine-mediated cell migration T Harada, V Kyttaris, Y Li, YT Juang, Y Wang, GC Tsokos Autoimmunity 40 (1), 1-8, 2007 | 137 | 2007 |
The CD38/NAD/SIRTUIN1/EZH2 axis mitigates cytotoxic CD8 T cell function and identifies patients with SLE prone to infections E Katsuyama, A Suarez-Fueyo, SJ Bradley, M Mizui, AV Marin, L Mulki, ... Cell reports 30 (1), 112-123. e4, 2020 | 136 | 2020 |
How signaling and gene transcription aberrations dictate the systemic lupus erythematosus T cell phenotype JC Crispín, VC Kyttaris, YT Juang, GC Tsokos Trends in immunology 29 (3), 110-115, 2008 | 125 | 2008 |
cAMP response element modulator α controls IL2 and IL17A expression during CD4 lineage commitment and subset distribution in lupus CM Hedrich, JC Crispin, T Rauen, C Ioannidis, SA Apostolidis, MS Lo, ... Proceedings of the National Academy of Sciences 109 (41), 16606-16611, 2012 | 120 | 2012 |
Increased levels of NF-ATc2 differentially regulate CD154 and IL-2 genes in T cells from patients with systemic lupus erythematosus VC Kyttaris, Y Wang, YT Juang, A Weinstein, GC Tsokos The Journal of immunology 178 (3), 1960-1966, 2007 | 104 | 2007 |
Ocular manifestations of systemic lupus erythematosus: a clinical review V Peponis, VC Kyttaris, C Tyradellis, I Vergados, NM Sitaras Lupus 15 (1), 3-12, 2006 | 104 | 2006 |
IL-23 limits the production of IL-2 and promotes autoimmunity in lupus H Dai, F He, GC Tsokos, VC Kyttaris The Journal of Immunology 199 (3), 903-910, 2017 | 99 | 2017 |
Expression of CD44 variant isoforms CD44v3 and CD44v6 is increased on T cells from patients with systemic lupus erythematosus and is correlated with disease activity JC Crispín, BT Keenan, MD Finnell, BL Bermas, P Schur, E Massarotti, ... Arthritis & Rheumatism 62 (5), 1431-1437, 2010 | 96 | 2010 |
Circulating Adiponectin Is Inversely Associated with Risk of Thyroid Cancer: In Vivo and in Vitro Studies N Mitsiades, K Pazaitou-Panayiotou, KN Aronis, HS Moon, ... The Journal of Clinical Endocrinology & Metabolism 96 (12), E2023-E2028, 2011 | 95 | 2011 |