Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13385* | 2021 |
RAS isoforms and mutations in cancer at a glance GA Hobbs, CJ Der, KL Rossman Journal of cell science 129 (7), 1287-1292, 2016 | 977 | 2016 |
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer KL Bryant, CA Stalnecker, D Zeitouni, JE Klomp, S Peng, AP Tikunov, ... Nature medicine 25 (4), 628-640, 2019 | 598 | 2019 |
Copper is required for oncogenic BRAF signalling and tumorigenesis DC Brady, MS Crowe, ML Turski, GA Hobbs, X Yao, A Chaikuad, S Knapp, ... Nature 509 (7501), 492-496, 2014 | 539 | 2014 |
Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer GA Hobbs, NM Baker, AM Miermont, RD Thurman, M Pierobon, TH Tran, ... Cancer discovery 10 (1), 104-123, 2020 | 166 | 2020 |
Altered RNA splicing by mutant p53 activates oncogenic RAS signaling in pancreatic cancer LF Escobar-Hoyos, A Penson, R Kannan, H Cho, CH Pan, RK Singh, ... Cancer cell 38 (2), 198-211. e8, 2020 | 143 | 2020 |
Redox regulation of Ras and Rho GTPases: mechanism and function L Mitchell, GA Hobbs, A Aghajanian, SL Campbell Antioxidants & redox signaling 18 (3), 250-258, 2013 | 101 | 2013 |
Tyrosine phosphorylation of tau accompanies disease progression in transgenic mouse models of tauopathy K Bhaskar, GA Hobbs, SH Yen, G Lee Neuropathology and applied neurobiology 36 (6), 462-477, 2010 | 100 | 2010 |
Rho GTPases, oxidation, and cell redox control GA Hobbs, B Zhou, AD Cox, SL Campbell Small GTPases 5 (2), e28579, 2014 | 85 | 2014 |
Selective targeting of the KRAS G12C mutant: kicking KRAS when it’s down GA Hobbs, A Wittinghofer, CJ Der Cancer Cell 29 (3), 251-253, 2016 | 75 | 2016 |
Evaluation of the selectivity and sensitivity of isoform-and mutation-specific RAS antibodies AM Waters, I Ozkan-Dagliyan, AV Vaseva, N Fer, LA Strathern, GA Hobbs, ... Science signaling 10 (498), eaao3332, 2017 | 62 | 2017 |
Redox regulation of Rac1 by thiol oxidation GA Hobbs, LE Mitchell, ME Arrington, HP Gunawardena, MJ DeCristo, ... Free Radical Biology and Medicine 79, 237-250, 2015 | 44 | 2015 |
Glutathiolated Ras: characterization and implications for Ras activation GA Hobbs, MG Bonini, HP Gunawardena, X Chen, SL Campbell Free Radical Biology and Medicine 57, 221-229, 2013 | 37 | 2013 |
STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer JE Lefler, CB MarElia-Bennett, KA Thies, BE Hildreth, SM Sharma, ... Life science alliance 5 (11), 2022 | 27 | 2022 |
RAS mutations are not created equal GA Hobbs, CJ Der Cancer discovery 9 (6), 696-698, 2019 | 27 | 2019 |
Not all RAS mutations are equal: a detailed review of the functional diversity of RAS hot spot mutations RA Burge, GA Hobbs Advances in Cancer Research 153, 29-61, 2022 | 22 | 2022 |
Functional and biological heterogeneity of KRASQ61 mutations MV Huynh, GA Hobbs, A Schaefer, M Pierobon, LM Carey, JN Diehl, ... Science signaling 15 (746), eabn2694, 2022 | 19 | 2022 |
Targeting p130Cas-and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition AM Waters, TO Khatib, B Papke, CM Goodwin, GA Hobbs, JN Diehl, ... Cell reports 35 (13), 2021 | 19 | 2021 |
Molecular characterization of the interaction of sialic acid with the periplasmic binding protein from Haemophilus ducreyi TG Setty, JC Mowers, AG Hobbs, SP Maiya, S Syed, RS Munson, ... Journal of Biological Chemistry 293 (52), 20073-20084, 2018 | 19 | 2018 |
Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants I Khan, A Koide, M Zuberi, G Ketavarapu, E Denbaum, KW Teng, JM Rhett, ... Cell reports 38 (6), 2022 | 15 | 2022 |