Biological insights from 108 schizophrenia-associated genetic loci C Pantelis, GN Papadimitriou, S Papiol, E Parkhomenko, MT Pato, ... Nature 511 (7510), 421-427, 2014 | 7441 | 2014 |
Genetics of rheumatoid arthritis contributes to biology and drug discovery Y Okada, D Wu, G Trynka, T Raj, C Terao, K Ikari, Y Kochi, K Ohmura, ... Nature 506 (7488), 376-381, 2014 | 2480 | 2014 |
Partitioning heritability by functional annotation using genome-wide association summary statistics HK Finucane, B Bulik-Sullivan, A Gusev, G Trynka, Y Reshef, PR Loh, ... Nature genetics 47 (11), 1228-1235, 2015 | 2220 | 2015 |
Genome-wide association analysis identifies 13 new risk loci for schizophrenia S Ripke, C O'dushlaine, K Chambert, JL Moran, AK Kähler, S Akterin, ... Nature genetics 45 (10), 1150-1159, 2013 | 1732 | 2013 |
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci EA Stahl, S Raychaudhuri, EF Remmers, G Xie, S Eyre, BP Thomson, Y Li, ... Nature genetics 42 (6), 508-514, 2010 | 1572 | 2010 |
A polygenic burden of rare disruptive mutations in schizophrenia SM Purcell, JL Moran, M Fromer, D Ruderfer, N Solovieff, P Roussos, ... Nature 506 (7487), 185-190, 2014 | 1555 | 2014 |
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection AF Pardiñas, P Holmans, AJ Pocklington, V Escott-Price, S Ripke, ... Nature genetics 50 (3), 381-389, 2018 | 1522 | 2018 |
Analysis of shared heritability in common disorders of the brain Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ... Science 360 (6395), eaap8757, 2018 | 1390 | 2018 |
Genome-wide association study identifies 30 loci associated with bipolar disorder EA Stahl, G Breen, AJ Forstner, A McQuillin, S Ripke, V Trubetskoy, ... Nature genetics 51 (5), 793-803, 2019 | 1384 | 2019 |
Modeling linkage disequilibrium increases accuracy of polygenic risk scores BJ Vilhjálmsson, J Yang, HK Finucane, A Gusev, S Lindström, S Ripke, ... The american journal of human genetics 97 (4), 576-592, 2015 | 1335 | 2015 |
Mapping genomic loci implicates genes and synaptic biology in schizophrenia V Trubetskoy, AF Pardiñas, T Qi, G Panagiotaropoulou, S Awasthi, ... Nature 604 (7906), 502-508, 2022 | 1245 | 2022 |
Gene expression elucidates functional impact of polygenic risk for schizophrenia M Fromer, P Roussos, SK Sieberts, JS Johnson, DH Kavanagh, ... Nature neuroscience 19 (11), 1442-1453, 2016 | 1074 | 2016 |
Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis S Raychaudhuri, C Sandor, EA Stahl, J Freudenberg, HS Lee, X Jia, ... Nature genetics 44 (3), 291-296, 2012 | 1063 | 2012 |
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal, Z Zhu, EM Tucker-Drob, ... Cell 179 (7), 1469-1482. e11, 2019 | 1061 | 2019 |
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects CR Marshall, DP Howrigan, D Merico, B Thiruvahindrapuram, W Wu, ... Nature genetics 49 (1), 27-35, 2017 | 928 | 2017 |
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics AN Barbeira, SP Dickinson, R Bonazzola, J Zheng, HE Wheeler, ... Nature communications 9 (1), 1825, 2018 | 871 | 2018 |
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology N Mullins, AJ Forstner, KS O’Connell, B Coombes, JRI Coleman, Z Qiao, ... Nature genetics 53 (6), 817-829, 2021 | 809 | 2021 |
Genetic analyses of diverse populations improves discovery for complex traits GL Wojcik, M Graff, KK Nishimura, R Tao, J Haessler, CR Gignoux, ... Nature 570 (7762), 514-518, 2019 | 797 | 2019 |
Progress and promise of genome-wide association studies for human complex trait genetics BE Stranger, EA Stahl, T Raj Genetics 187 (2), 367-383, 2011 | 764 | 2011 |
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis S Eyre, J Bowes, D Diogo, A Lee, A Barton, P Martin, A Zhernakova, ... Nature genetics 44 (12), 1336-1340, 2012 | 762 | 2012 |