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Ammon E. Posey
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A lethal de novo mutation in the middle domain of the dynamin-related GTPase Drp1 impairs higher order assembly and mitochondrial division
CR Chang, CM Manlandro, D Arnoult, J Stadler, AE Posey, RB Hill, ...
Journal of biological chemistry 285 (42), 32494-32503, 2010
1942010
Phase separation of intrinsically disordered proteins
AE Posey, AS Holehouse, RV Pappu
Methods in enzymology 611, 1-30, 2018
1652018
Arginine-enriched mixed-charge domains provide cohesion for nuclear speckle condensation
JA Greig, TA Nguyen, M Lee, AS Holehouse, AE Posey, RV Pappu, ...
Molecular cell 77 (6), 1237-1250. e4, 2020
1522020
Profilin reduces aggregation and phase separation of huntingtin N-terminal fragments by preferentially binding to soluble monomers and oligomers
AE Posey, KM Ruff, TS Harmon, SL Crick, A Li, MI Diamond, RV Pappu
Journal of Biological Chemistry 293 (10), 3734-3746, 2018
1132018
Self-assembly of block heterochiral peptides into helical tapes
TM Clover, CL O’Neill, R Appavu, G Lokhande, AK Gaharwar, AE Posey, ...
Journal of the American Chemical Society 142 (47), 19809-19813, 2020
612020
Dilute phase oligomerization can oppose phase separation and modulate material properties of a ribonucleoprotein condensate
I Seim, AE Posey, WT Snead, BM Stormo, D Klotsa, RV Pappu, ...
Proceedings of the National Academy of Sciences 119 (13), e2120799119, 2022
532022
Inhibition of amyloid beta fibril formation by monomeric human transthyretin
K Garai, AE Posey, X Li, JN Buxbaum, RV Pappu
Protein Science 27 (7), 1252-1261, 2018
432018
Molecular motor Dnm1 synergistically induces membrane curvature to facilitate mitochondrial fission
MW Lee, EY Lee, GH Lai, NW Kennedy, AE Posey, W Xian, AL Ferguson, ...
ACS central science 3 (11), 1156-1167, 2017
332017
Glycine-Rich Peptides from FUS Have an Intrinsic Ability to Self-Assemble into Fibers and Networked Fibrils: Published as part of the Biochemistry virtual special …
M Kar, AE Posey, F Dar, AA Hyman, RV Pappu
Biochemistry 60 (43), 3213-3222, 2021
262021
GADIS: Algorithm for designing sequences to achieve target secondary structure profiles of intrinsically disordered proteins
TS Harmon, MD Crabtree, SL Shammas, AE Posey, J Clarke, RV Pappu
Protein Engineering, Design and Selection 29 (9), 339-346, 2016
232016
Quantifying charge state heterogeneity for proteins with multiple ionizable residues
MJ Fossat, AE Posey, RV Pappu
Biophysical Journal 120 (24), 5438-5453, 2021
192021
Mechanistic inferences from analysis of measurements of protein phase transitions in live cells
AE Posey, KM Ruff, JM Lalmansingh, TS Kandola, JJ Lange, R Halfmann, ...
Journal of molecular biology 433 (12), 166848, 2021
182021
Dynamical control enables the formation of demixed biomolecular condensates
AZ Lin, KM Ruff, F Dar, A Jalihal, MR King, JM Lalmansingh, AE Posey, ...
Nature Communications 14 (1), 7678, 2023
172023
A targeted mutation identified through pKa measurements indicates a postrecruitment role for Fis1 in yeast mitochondrial fission
M Koppenol-Raab, MC Harwig, AE Posey, JM Egner, KR MacKenzie, ...
Journal of Biological Chemistry 291 (39), 20329-20344, 2016
162016
Gold nanoshell assembly on a ferritin protein employed as a bio-template
JW Kim, AE Posey, GD Watt, SH Choi, PT Lillehei
Journal of Nanoscience and Nanotechnology 10 (3), 1771-1777, 2010
142010
Methods in Enzymology
AE Posey, AS Holehouse, RV Pappu
Elsevier, Inc 611, 1-30, 2018
132018
Quantifying coexistence concentrations in multi-component phase-separating systems using analytical HPLC
A Bremer, AE Posey, MB Borgia, WM Borcherds, M Farag, RV Pappu, ...
Biomolecules 12 (10), 1480, 2022
122022
Uncovering the contributions of charge regulation to the stability of single alpha helices
MJ Fossat, AE Posey, RV Pappu
Chemphyschem 24 (7), e202200746, 2023
82023
Sequence-specific interactions determine viscoelasticity and aging dynamics of protein condensates
I Alshareedah, WM Borcherds, SR Cohen, A Singh, AE Posey, M Farag, ...
bioRxiv, 2023.04. 06.535902, 2023
72023
A first glimpse of nucleation of phase transitions in living cells
AE Posey, RV Pappu
Molecular cell 71 (1), 1-3, 2018
22018
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