Oncometabolite d-2HG alters T cell metabolism to impair CD8+ T cell function G Notarangelo, JB Spinelli, EM Perez, GJ Baker, K Kurmi, I Elia, ... Science 377 (6614), 1519-1529, 2022 | 138 | 2022 |
Molecular imaging of biological samples on nanophotonic laser desorption ionization platforms SA Stopka, C Rong, AR Korte, S Yadavilli, J Nazarian, TT Razunguzwa, ... Angewandte Chemie International Edition 55 (14), 4482-4486, 2016 | 101 | 2016 |
De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma DD Shi, MR Savani, MM Levitt, AC Wang, JE Endress, CE Bird, J Buehler, ... Cancer cell 40 (9), 939-956. e16, 2022 | 64 | 2022 |
Laser‐ablation electrospray ionization mass spectrometry with ion mobility separation reveals metabolites in the symbiotic interactions of soybean roots and rhizobia SA Stopka, BJ Agtuca, DW Koppenaal, L Paša‐Tolić, G Stacey, A Vertes, ... The Plant Journal 91 (2), 340-354, 2017 | 54 | 2017 |
Ambient metabolic profiling and imaging of biological samples with ultrahigh molecular resolution using laser ablation electrospray ionization 21 Tesla FTICR mass spectrometry SA Stopka, LZ Samarah, JB Shaw, AV Liyu, D Veličković, BJ Agtuca, ... Analytical chemistry 91 (8), 5028-5035, 2019 | 52 | 2019 |
Observed metabolic asymmetry within soybean root nodules reflects unexpected complexity in rhizobacteria-legume metabolite exchange D Veličković, BJ Agtuca, SA Stopka, A Vertes, DW Koppenaal, ... The ISME Journal 12 (9), 2335-2338, 2018 | 51 | 2018 |
Metabolic Noise and Distinct Subpopulations Observed by Single Cell LAESI Mass Spectrometry of Plant Cells in situ SA Stopka, R Khattar, BJ Agtuca, CR Anderton, L Paša-Tolić, G Stacey, ... Frontiers in plant science 9, 1646, 2018 | 49 | 2018 |
Heterogeneous delivery across the blood-brain barrier limits the efficacy of an EGFR-targeting antibody drug conjugate in glioblastoma BM Marin, KA Porath, S Jain, M Kim, JE Conage-Pough, JH Oh, CL Miller, ... Neuro-oncology 23 (12), 2042-2053, 2021 | 46 | 2021 |
Single-cell metabolic profiling: metabolite formulas from isotopic fine structures in heterogeneous plant cell populations LZ Samarah, R Khattar, TH Tran, SA Stopka, CA Brantner, P Parlanti, ... Analytical Chemistry 92 (10), 7289-7298, 2020 | 46 | 2020 |
Large-scale metabolite analysis of standards and human serum by laser desorption ionization mass spectrometry from silicon nanopost arrays AR Korte, SA Stopka, N Morris, T Razunguzwa, A Vertes Analytical chemistry 88 (18), 8989-8996, 2016 | 46 | 2016 |
Clinical efficacy of ONC201 in H3K27M-mutant diffuse midline gliomas is driven by disruption of integrated metabolic and epigenetic pathways S Venneti, AR Kawakibi, S Ji, SM Waszak, SR Sweha, M Mota, M Pun, ... Cancer discovery 13 (11), 2370-2393, 2023 | 45 | 2023 |
A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma S Pal, JP Kaplan, H Nguyen, SA Stopka, MR Savani, MS Regan, ... Cancer Cell 40 (9), 957-972. e10, 2022 | 44 | 2022 |
Chronic convection-enhanced delivery of topotecan for patients with recurrent glioblastoma: a first-in-patient, single-centre, single-arm, phase 1b trial EF Spinazzi, MG Argenziano, PS Upadhyayula, MA Banu, JA Neira, ... The Lancet Oncology 23 (11), 1409-1418, 2022 | 37 | 2022 |
Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma S Coy, S Wang, SA Stopka, JR Lin, C Yapp, CC Ritch, L Salhi, GJ Baker, ... Nature communications 13 (1), 4814, 2022 | 35 | 2022 |
Optical microscopy-guided laser ablation electrospray ionization ion mobility mass spectrometry: ambient single cell metabolomics with increased confidence in molecular … MJ Taylor, S Mattson, A Liyu, SA Stopka, YM Ibrahim, A Vertes, ... Metabolites 11 (4), 200, 2021 | 30 | 2021 |
Trace analysis and reaction monitoring by nanophotonic ionization mass spectrometry from elevated bowtie and silicon nanopost arrays SA Stopka, XA Holmes, AR Korte, LR Compton, ST Retterer, A Vertes Advanced Functional Materials 28 (29), 1801730, 2018 | 30 | 2018 |
BAF complex maintains glioma stem cells in pediatric H3K27M glioma E Panditharatna, JG Marques, T Wang, MC Trissal, I Liu, L Jiang, A Beck, ... Cancer discovery 12 (12), 2880-2905, 2022 | 28 | 2022 |
Metabolomic profiling of wild‐type and mutant soybean root nodules using laser‐ablation electrospray ionization mass spectrometry reveals altered metabolism BJ Agtuca, SA Stopka, S Evans, L Samarah, Y Liu, D Xu, MG Stacey, ... The Plant Journal 103 (5), 1937-1958, 2020 | 28 | 2020 |
In-Situ Metabolomic Analysis of Setaria viridis Roots Colonized by Beneficial Endophytic Bacteria BJ Agtuca, SA Stopka, TR Tuleski, FP do Amaral, S Evans, Y Liu, D Xu, ... Molecular Plant-Microbe Interactions 33 (2), 272-283, 2020 | 27 | 2020 |
A non-dividing cell population with high pyruvate dehydrogenase kinase activity regulates metabolic heterogeneity and tumorigenesis in the intestine C Sebastian, C Ferrer, M Serra, JE Choi, N Ducano, A Mira, MS Shah, ... Nature Communications 13 (1), 1503, 2022 | 26 | 2022 |