Expression of Tn, sialosyl-Tn, and T antigens in human colon cancer SH Itzkowitz, M Yuan, CK Montgomery, T Kjeldsen, HK Takahashi, ... Cancer Research 49 (1), 197-204, 1989 | 673 | 1989 |
Preparation and Characterization of Monoclonal Antibodies Directed to the Tumor-associated O-linked Sialosyl-2→6 α-N-Acetylgalactosaminyl (Sialosyl-Tn) Epitope T Kjeldsen, H Clausen, S Hirohashi, T Ogawa, H Iijima, S Hakomori Cancer research 48 (8), 2214-2220, 1988 | 551 | 1988 |
Yeast secretory expression of insulin precursors T Kjeldsen Applied microbiology and biotechnology 54, 277-286, 2000 | 285 | 2000 |
Alanine scanning mutagenesis of insulin C Kristensen, T Kjeldsen, FC Wiberg, L Schäffer, M Hach, S Havelund, ... Journal of Biological Chemistry 272 (20), 12978-12983, 1997 | 268 | 1997 |
The ligand specificities of the insulin receptor and the insulin-like growth factor I receptor reside in different regions of a common binding site. T Kjeldsen, AS Andersen, FC Wiberg, JS Rasmussen, L Schäffer, ... Proceedings of the National Academy of Sciences 88 (10), 4404-4408, 1991 | 196 | 1991 |
Secretory expression and characterization of insulin in Pichia pastoris T Kjeldsen, AF Pettersson, M Hach Biotechnology and applied biochemistry 29 (1), 79-86, 1999 | 166 | 1999 |
Expression of Tn, sialosyl Tn, and T antigens in human pancreas S Itzkowitz, T Kjeldsen, A Friera, SI Hakomori, US Yang, YS Kim Gastroenterology 100 (6), 1691-1700, 1991 | 163 | 1991 |
A panel of monoclonal antibodies for the type I insulin-like growth factor receptor. Epitope mapping, effects on ligand binding, and biological activity. MA Soos, CE Field, R Lammers, A Ullrich, B Zhang, RA Roth, ... Journal of Biological Chemistry 267 (18), 12955-12963, 1992 | 148 | 1992 |
Structure-function relationship of the insulin-like growth factor-I receptor tyrosine kinase. M Grønborg, BS Wulff, JS Rasmussen, T Kjeldsen, S Gammeltoft Journal of Biological Chemistry 268 (31), 23435-23440, 1993 | 139 | 1993 |
Identification of determinants that confer ligand specificity on the insulin receptor. AS Andersen, T Kjeldsen, FC Wiberg, H Vissing, L Schäffer, ... Journal of Biological Chemistry 267 (19), 13681-13686, 1992 | 105 | 1992 |
Molecular and pharmacological characterization of insulin icodec: a new basal insulin analog designed for once-weekly dosing E Nishimura, L Pridal, T Glendorf, BF Hansen, F Hubálek, T Kjeldsen, ... BMJ Open Diabetes Research and Care 9 (1), e002301, 2021 | 101 | 2021 |
Molecular engineering of insulin icodec, the first acylated insulin analog for once-weekly administration in humans TB Kjeldsen, F Hubalek, CU Hjørringgaard, TM Tagmose, E Nishimura, ... Journal of Medicinal Chemistry 64 (13), 8942-8950, 2021 | 98 | 2021 |
Intracellular retention of newly synthesized insulin in yeast is caused by endoproteolytic processing in the Golgi complex B Zhang, A Chang, TB Kjeldsen, P Arvan The Journal of cell biology 153 (6), 1187-1198, 2001 | 96 | 2001 |
A removable spacer peptide in an α-factor-leader/insulin precursor fusion protein improves processing and concomitant yield of the insulin precursor in Saccharomyces cerevisiae T Kjeldsen, J Brandt, AS Andersen, M Egel-Mitani, M Hach, AF Pettersson, ... Gene 170 (1), 107-112, 1996 | 96 | 1996 |
Changing the insulin receptor to possess insulin-like growth factor I ligand specificity AS Andersen, T Kjeldsen, FC Wiberg, PM Christensen, ... Biochemistry 29 (32), 7363-7366, 1990 | 95 | 1990 |
A single-chain insulin-like growth factor I/insulin hybrid binds with high affinity to the insulin receptor C Kristensen, AS Andersen, M Hach, FC Wiberg, L Schäffer, T Kjeldsen Biochemical Journal 305 (3), 981-986, 1995 | 90 | 1995 |
Engineering-enhanced protein secretory expression in yeast with application to insulin T Kjeldsen, S Ludvigsen, I Diers, P Balschmidt, AR Sørensen, ... Journal of Biological Chemistry 277 (21), 18245-18248, 2002 | 89 | 2002 |
Insulin analog with additional disulfide bond has increased stability and preserved activity TN Vinther, M Norrman, U Ribel, K Huus, M Schlein, DB Steensgaard, ... Protein Science 22 (3), 296-305, 2013 | 81 | 2013 |
Nuclear volume and expression of T‐antigen, sialosyl‐Tn‐antigen, and Tn‐antigen in carcinoma of the human bladder. Relation to tumor recurrence and progression NC Langkilde, H Wolf, H Clausen, T Kjeldsen, TF Ørntoft Cancer 69 (1), 219-227, 1992 | 70 | 1992 |
Importance of the solvent-exposed residues of the insulin B chain α-helix for receptor binding T Glendorf, AR Sørensen, E Nishimura, I Pettersson, T Kjeldsen Biochemistry 47 (16), 4743-4751, 2008 | 66 | 2008 |