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Thomas Kjeldsen
Thomas Kjeldsen
其他姓名Thomas B. Kjeldsen, Thomas børglum Kjeldsen
在 novonordisk.com 的电子邮件经过验证
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引用次数
引用次数
年份
Expression of Tn, sialosyl-Tn, and T antigens in human colon cancer
SH Itzkowitz, M Yuan, CK Montgomery, T Kjeldsen, HK Takahashi, ...
Cancer Research 49 (1), 197-204, 1989
6731989
Preparation and Characterization of Monoclonal Antibodies Directed to the Tumor-associated O-linked Sialosyl-2→6 α-N-Acetylgalactosaminyl (Sialosyl-Tn) Epitope
T Kjeldsen, H Clausen, S Hirohashi, T Ogawa, H Iijima, S Hakomori
Cancer research 48 (8), 2214-2220, 1988
5511988
Yeast secretory expression of insulin precursors
T Kjeldsen
Applied microbiology and biotechnology 54, 277-286, 2000
2852000
Alanine scanning mutagenesis of insulin
C Kristensen, T Kjeldsen, FC Wiberg, L Schäffer, M Hach, S Havelund, ...
Journal of Biological Chemistry 272 (20), 12978-12983, 1997
2681997
The ligand specificities of the insulin receptor and the insulin-like growth factor I receptor reside in different regions of a common binding site.
T Kjeldsen, AS Andersen, FC Wiberg, JS Rasmussen, L Schäffer, ...
Proceedings of the National Academy of Sciences 88 (10), 4404-4408, 1991
1961991
Secretory expression and characterization of insulin in Pichia pastoris
T Kjeldsen, AF Pettersson, M Hach
Biotechnology and applied biochemistry 29 (1), 79-86, 1999
1661999
Expression of Tn, sialosyl Tn, and T antigens in human pancreas
S Itzkowitz, T Kjeldsen, A Friera, SI Hakomori, US Yang, YS Kim
Gastroenterology 100 (6), 1691-1700, 1991
1631991
A panel of monoclonal antibodies for the type I insulin-like growth factor receptor. Epitope mapping, effects on ligand binding, and biological activity.
MA Soos, CE Field, R Lammers, A Ullrich, B Zhang, RA Roth, ...
Journal of Biological Chemistry 267 (18), 12955-12963, 1992
1481992
Structure-function relationship of the insulin-like growth factor-I receptor tyrosine kinase.
M Grønborg, BS Wulff, JS Rasmussen, T Kjeldsen, S Gammeltoft
Journal of Biological Chemistry 268 (31), 23435-23440, 1993
1391993
Identification of determinants that confer ligand specificity on the insulin receptor.
AS Andersen, T Kjeldsen, FC Wiberg, H Vissing, L Schäffer, ...
Journal of Biological Chemistry 267 (19), 13681-13686, 1992
1051992
Molecular and pharmacological characterization of insulin icodec: a new basal insulin analog designed for once-weekly dosing
E Nishimura, L Pridal, T Glendorf, BF Hansen, F Hubálek, T Kjeldsen, ...
BMJ Open Diabetes Research and Care 9 (1), e002301, 2021
1012021
Molecular engineering of insulin icodec, the first acylated insulin analog for once-weekly administration in humans
TB Kjeldsen, F Hubalek, CU Hjørringgaard, TM Tagmose, E Nishimura, ...
Journal of Medicinal Chemistry 64 (13), 8942-8950, 2021
982021
Intracellular retention of newly synthesized insulin in yeast is caused by endoproteolytic processing in the Golgi complex
B Zhang, A Chang, TB Kjeldsen, P Arvan
The Journal of cell biology 153 (6), 1187-1198, 2001
962001
A removable spacer peptide in an α-factor-leader/insulin precursor fusion protein improves processing and concomitant yield of the insulin precursor in Saccharomyces cerevisiae
T Kjeldsen, J Brandt, AS Andersen, M Egel-Mitani, M Hach, AF Pettersson, ...
Gene 170 (1), 107-112, 1996
961996
Changing the insulin receptor to possess insulin-like growth factor I ligand specificity
AS Andersen, T Kjeldsen, FC Wiberg, PM Christensen, ...
Biochemistry 29 (32), 7363-7366, 1990
951990
A single-chain insulin-like growth factor I/insulin hybrid binds with high affinity to the insulin receptor
C Kristensen, AS Andersen, M Hach, FC Wiberg, L Schäffer, T Kjeldsen
Biochemical Journal 305 (3), 981-986, 1995
901995
Engineering-enhanced protein secretory expression in yeast with application to insulin
T Kjeldsen, S Ludvigsen, I Diers, P Balschmidt, AR Sørensen, ...
Journal of Biological Chemistry 277 (21), 18245-18248, 2002
892002
Insulin analog with additional disulfide bond has increased stability and preserved activity
TN Vinther, M Norrman, U Ribel, K Huus, M Schlein, DB Steensgaard, ...
Protein Science 22 (3), 296-305, 2013
812013
Nuclear volume and expression of T‐antigen, sialosyl‐Tn‐antigen, and Tn‐antigen in carcinoma of the human bladder. Relation to tumor recurrence and progression
NC Langkilde, H Wolf, H Clausen, T Kjeldsen, TF Ørntoft
Cancer 69 (1), 219-227, 1992
701992
Importance of the solvent-exposed residues of the insulin B chain α-helix for receptor binding
T Glendorf, AR Sørensen, E Nishimura, I Pettersson, T Kjeldsen
Biochemistry 47 (16), 4743-4751, 2008
662008
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