Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017α and P450 aromatase localized in neurons Y Hojo, T Hattori, T Enami, A Furukawa, K Suzuki, H Ishii, H Mukai, ... Proceedings of the National Academy of Sciences 101 (3), 865-870, 2004 | 766 | 2004 |
Rapid modulation of long‐term depression and spinogenesis via synaptic estrogen receptors in hippocampal principal neurons H Mukai, T Tsurugizawa, G Murakami, S Kominami, H Ishii, ... Journal of neurochemistry 100 (4), 950-967, 2007 | 258 | 2007 |
Estrogen synthesis in the brain—role in synaptic plasticity and memory Y Hojo, G Murakami, H Mukai, S Higo, Y Hatanaka, M Ogiue-Ikeda, H Ishii, ... Molecular and cellular endocrinology 290 (1-2), 31-43, 2008 | 257 | 2008 |
Comparison between hippocampus-synthesized and circulation-derived sex steroids in the hippocampus Y Hojo, S Higo, H Ishii, Y Ooishi, H Mukai, G Murakami, T Kominami, ... Endocrinology 150 (11), 5106-5112, 2009 | 180 | 2009 |
Hippocampal cytochrome P450s synthesize brain neurosteroids which are paracrine neuromodulators of synaptic signal transduction K Shibuya, N Takata, Y Hojo, A Furukawa, N Yasumatsu, T Kimoto, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1619 (3), 301-316, 2003 | 167 | 2003 |
Local neurosteroid production in the hippocampus: influence on synaptic plasticity of memory H Mukai, T Tsurugizawa, M Ogiue-Ikeda, G Murakami, Y Hojo, H Ishii, ... Neuroendocrinology 84 (4), 255-263, 2007 | 136 | 2007 |
Hippocampal synthesis of sex steroids and corticosteroids: essential for modulation of synaptic plasticity Y Hojo, S Higo, S Kawato, Y Hatanaka, Y Ooishi, G Murakami, H Ishii, ... Frontiers in endocrinology 2, 43, 2011 | 98 | 2011 |
Gene structures, biochemical characterization and distribution of rat melatonin receptors H Ishii, N Tanaka, M Kobayashi, M Kato, Y Sakuma The Journal of Physiological Sciences 59, 37-47, 2009 | 95 | 2009 |
Retinoic acid stimulates 17β-estradiol and testosterone synthesis in rat hippocampal slice cultures E Munetsuna, Y Hojo, M Hattori, H Ishii, S Kawato, A Ishida, ... Endocrinology 150 (9), 4260-4269, 2009 | 89 | 2009 |
Activation of A‐Type γ‐Amino Butyric Acid Receptors Excites Gonadotrophin‐Releasing Hormone Neurones Isolated from Adult Rats C Yin, H Ishii, N Tanaka, Y Sakuma, M Kato Journal of neuroendocrinology 20 (5), 566-575, 2008 | 67 | 2008 |
Semicomprehensive analysis of the postnatal age-related changes in the mRNA expression of sex steroidogenic enzymes and sex steroid receptors in the male rat hippocampus T Kimoto, H Ishii, S Higo, Y Hojo, S Kawato Endocrinology 151 (12), 5795-5806, 2010 | 55 | 2010 |
17β-Estradiol at Physiological Concentrations Augments Ca2+-Activated K+ Currents via Estrogen Receptor β in the Gonadotropin-Releasing Hormone Neuronal … I Nishimura, K Ui-Tei, K Saigo, H Ishii, Y Sakuma, M Kato Endocrinology 149 (2), 774-782, 2008 | 50 | 2008 |
Endogenous synthesis of corticosteroids in the hippocampus S Higo, Y Hojo, H Ishii, Y Komatsuzaki, Y Ooishi, G Murakami, H Mukai, ... PLoS One 6 (7), e21631, 2011 | 43 | 2011 |
Role of cytochrome p450 in synaptocrinology: endogenous estrogen synthesis in the brain hippocampus G Murakami, N Tanabe, H Ishii, M Ogiue-Ikeda, T Tsurugizawa, H Mukai, ... Drug metabolism reviews 38 (3), 353-369, 2006 | 40 | 2006 |
Enhancement of nitric oxide production by association of nitric oxide synthase with N‐methyl‐d‐aspartate receptors via postsynaptic density 95 in genetically … H Ishii, K Shibuya, Y Ohta, H Mukai, S Uchino, N Takata, JA Rose, ... Journal of neurochemistry 96 (6), 1531-1539, 2006 | 39 | 2006 |
Alternative promoter usage and alternative splicing of the rat estrogen receptor α gene generate numerous mRNA variants with distinct 5′-ends H Ishii, M Kobayashi, Y Sakuma The Journal of Steroid Biochemistry and Molecular Biology 118 (1-2), 59-69, 2010 | 37 | 2010 |
Comparison of sex-steroid synthesis between neonatal and adult rat hippocampus S Higo, Y Hojo, H Ishii, T Kominami, K Nakajima, D Poirier, T Kimoto, ... Biochemical and biophysical research communications 385 (1), 62-66, 2009 | 31 | 2009 |
Identification of novel splicing events and post-transcriptional regulation of human estrogen receptor α F isoforms M Kobayashi, H Ishii, Y Sakuma Molecular and cellular endocrinology 333 (1), 55-61, 2011 | 28 | 2011 |
GnRH (1-5), a metabolite of gonadotropin-releasing hormone, enhances luteinizing hormone release via activation of kisspeptin neurons in female rats N Ieda, S Minabe, K Ikegami, Y Watanabe, Y Sugimoto, A Sugimoto, ... Endocrine Journal 67 (4), 409-418, 2020 | 23 | 2020 |
Rat GnRH neurons exhibit large conductance voltage-and Ca2+-Activated K+ (BK) currents and express BK channel mRNAs Y Hiraizumi, I Nishimura, H Ishii, N Tanaka, T Takeshita, Y Sakuma, ... The journal of physiological sciences 58 (1), 21-29, 2008 | 22 | 2008 |