| Metabolomic analysis reveals increased aerobic glycolysis and amino acid deficit in a cellular model of amyotrophic lateral sclerosis GN Valbuena, M Rizzardini, S Cimini, AP Siskos, C Bendotti, L Cantoni, ... Molecular neurobiology 53, 2222-2240, 2016 | 78 | 2016 |
| Systematic integration of molecular profiles identifies miR-22 as a regulator of lipid and folate metabolism in breast cancer cells C Koufaris, GN Valbuena, Y Pomyen, GD Tredwell, E Nevedomskaya, ... Oncogene 35 (21), 2766-2776, 2016 | 67 | 2016 |
| Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia EG Vazquez, N Nasreddin, GN Valbuena, EJ Mulholland, ... Cell stem cell 29 (8), 1213-1228. e8, 2022 | 57 | 2022 |
| Suppression of MTHFD2 in MCF-7 breast cancer cells increases glycolysis, dependency on exogenous glycine, and sensitivity to folate depletion C Koufaris, S Gallage, T Yang, CH Lau, GN Valbuena, HC Keun Journal of proteome research 15 (8), 2618-2625, 2016 | 46 | 2016 |
| MicroRNAs as biomarkers for prostate cancer prognosis: a systematic review and a systematic reanalysis of public data S Rana, GN Valbuena, E Curry, CL Bevan, HC Keun British journal of cancer 126 (3), 502-513, 2022 | 43 | 2022 |
| Bone morphogenetic protein pathway antagonism by Grem1 regulates epithelial cell fate in intestinal regeneration MAJ Koppens, H Davis, GN Valbuena, EJ Mulholland, N Nasreddin, ... Gastroenterology 161 (1), 239-254. e9, 2021 | 41 | 2021 |
| Indisulam targets RNA splicing and metabolism to serve as a therapeutic strategy for high-risk neuroblastoma A Nijhuis, A Sikka, O Yogev, L Herendi, C Balcells, Y Ma, E Poon, ... Nature Communications 13 (1), 1380, 2022 | 40 | 2022 |
| The coordinated action of VCP/p97 and GCN2 regulates cancer cell metabolism and proteostasis during nutrient limitation K Parzych, P Saavedra-García, GN Valbuena, HA Al-Sadah, ... Oncogene 38 (17), 3216-3231, 2019 | 39 | 2019 |
| Inadequate fine-tuning of protein synthesis and failure of amino acid homeostasis following inhibition of the ATPase VCP/p97 K Parzych, TM Chinn, Z Chen, S Loaiza, F Porsch, GN Valbuena, ... Cell death & disease 6 (12), e2031-e2031, 2015 | 34 | 2015 |
| Spinal cord metabolic signatures in models of fast-and slow-progressing SOD1G93A amyotrophic lateral sclerosis GN Valbuena, L Cantoni, M Tortarolo, C Bendotti, HC Keun Frontiers in neuroscience 13, 1276, 2019 | 19 | 2019 |
| The impact of p53 on aristolochic acid I-induced nephrotoxicity and DNA damage in vivo and in vitro M Sborchia, EG De Prez, MH Antoine, L Bienfait, R Indra, G Valbuena, ... Archives of toxicology 93, 3345-3366, 2019 | 18 | 2019 |
| Altered Metabolic Profiles Associate with Toxicity in SOD1G93A Astrocyte-Neuron Co-Cultures GN Valbuena, M Tortarolo, C Bendotti, L Cantoni, HC Keun Scientific Reports 7 (1), 50, 2017 | 16 | 2017 |
| Tracing Nutrient Flux Following Monocarboxylate Transporter-1 Inhibition with AZD3965 M Braga, M Kaliszczak, L Carroll, ZT Schug, K Heinzmann, N Baxan, ... Cancers 12 (6), 1703, 2020 | 11 | 2020 |
| The 14q32 maternally imprinted locus is a major source of longitudinally stable circulating microRNAs as measured by small RNA sequencing GN Valbuena, S Apostolidou, R Roberts, J Barnes, W Alderton, L Harper, ... Scientific reports 9 (1), 15787, 2019 | 11 | 2019 |
| Profiling the metabolic signature of senescence FM Geier, S Fuchs, G Valbuena, AM Leroi, JG Bundy Cell Senescence: Methods and Protocols, 355-371, 2013 | 4 | 2013 |
| Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1 C Beach, D MacLean, D Majorova, S Melemenidis, DK Nambiar, RK Kim, ... The Journal of clinical investigation 133 (23), 2023 | 1 | 2023 |
| Metabolomic studies of amyotrophic lateral sclerosis G Valbuena Imperial College London, 2015 | 1 | 2015 |
| GREMLIN1 disrupts intestinal epithelial-mesenchymal crosstalk to induce a wnt-dependent ectopic stem cell niche via stromal remodelling EJ Mulholland, HL Belnoue-Davis, GN Valbuena, N Gunduz, A Ligeza, ... bioRxiv, 2024.04. 28.591245, 2024 | | 2024 |
