Lone pair− aromatic interactions: To stabilize or not to stabilize M Egli, S Sarkhel Accounts of chemical research 40 (3), 197-205, 2007 | 589 | 2007 |
N H… O, O H… O, and C H… O hydrogen bonds in protein–ligand complexes: Strong and weak interactions in molecular recognition S Sarkhel, GR Desiraju Proteins: Structure, Function, and Bioinformatics 54 (2), 247-259, 2004 | 314 | 2004 |
Water− Nucleobase “Stacking”: H− π and lone pair− π interactions in the atomic resolution crystal structure of an RNA pseudoknot S Sarkhel, A Rich, M Egli Journal of the American Chemical Society 125 (30), 8998-8999, 2003 | 156 | 2003 |
Novel biodegradable polyesteramide microspheres for controlled drug delivery in Ophthalmology V Andrés-Guerrero, M Zong, E Ramsay, B Rojas, S Sarkhel, B Gallego, ... Journal of Controlled Release 211, 105-117, 2015 | 109 | 2015 |
Formulation and stability of cytokine therapeutics T Lipiäinen, M Peltoniemi, S Sarkhel, T Yrjönen, H Vuorela, A Urtti, ... Journal of pharmaceutical sciences 104 (2), 307-326, 2015 | 88 | 2015 |
A convenient synthesis and hepatoprotective activity of imidazo [1, 2-c] pyrimido [5, 4-e] pyrimidine, tetraazaacenaphthene and tetraazaphenalene from cyclic ketene aminals … VJ Ram, A Goel, S Sarkhel, PR Maulik Bioorganic & medicinal chemistry 10 (5), 1275-1280, 2002 | 86 | 2002 |
Expression without boundaries: cell-free protein synthesis in pharmaceutical research MG Casteleijn, A Urtti, S Sarkhel International journal of pharmaceutics 440 (1), 39-47, 2013 | 72 | 2013 |
2 ‘-Fluoroarabino-and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H F Li, S Sarkhel, CJ Wilds, Z Wawrzak, TP Prakash, M Manoharan, M Egli Biochemistry 45 (13), 4141-4152, 2006 | 61 | 2006 |
A stacked pyrazolo [3, 4-d] pyrimidine-based flexible molecule PR Maulik, K Avasthi, G Biswas, S Biswas, DS Rawat, S Sarkhel, ... Acta Crystallographica Section C: Crystal Structure Communications 54 (2 …, 1998 | 43 | 1998 |
A facile access to the synthesis of functionalised unsymmetrical biaryls from 2 H-pyran-2-ones through carbanion induced C–C bond formation VJ Ram, M Nath, P Srivastava, S Sarkhel, PR Maulik Journal of the Chemical Society, Perkin Transactions 1, 3719-3723, 2000 | 41 | 2000 |
Structure-based drug design: synthesis, crystal structure, biological evaluation and docking studies of mono-and bis-benzo [b] oxepines as non-steroidal estrogens S Sarkhel, A Sharon, V Trivedi, PR Maulik, MM Singh, P Venugopalan, ... Bioorganic & medicinal chemistry 11 (23), 5025-5033, 2003 | 31 | 2003 |
Release of functional dexamethasone by intracellular enzymes: A modular peptide-based strategy for ocular drug delivery M Bhattacharya, A Sadeghi, S Sarkhel, M Hagström, S Bahrpeyma, ... Journal of Controlled Release 327, 584-594, 2020 | 30 | 2020 |
1H NMR and X-ray crystallographic analysis of 1, 2-bis (4, 6-diethylthio-1H-pyrazolo [3, 4-d] pyrimidin-1-yl) ethane and its ‘propylene linker’-analog: molecular recognition … K Avasthi, DS Rawat, PR Maulik, S Sarkhel, CK Broder, JAK Howard Tetrahedron Letters 42 (40), 7115-7117, 2001 | 30 | 2001 |
Disappearance of intramolecular stacking due to one-atom movement or increment of apropylene linker'in pyrazolo [3, 4-d] pyrimidine-based flexible models PR Maulik, K Avasthi, S Sarkhel, T Chandra, DS Rawat, B Logsdon, ... Acta Crystallographica Section C: Crystal Structure Communications 56 (11 …, 2000 | 25 | 2000 |
Codon optimization and factorial screening for enhanced soluble expression of human ciliary neurotrophic factor in Escherichia coli JM Itkonen, A Urtti, LE Bird, S Sarkhel BMC biotechnology 14, 1-11, 2014 | 21 | 2014 |
Resolution, molecular structure and biological activities of the D-and L-enantiomers of potent anti-implantation agent, DL-2-[4-(2-piperidinoethoxy) phenyl]-3-phenyl-2H-1 … K Hajela, J Pandey, A Dwivedy, JD Dhar, S Sarkhel, PR Maulik, ... Bioorganic & medicinal chemistry 7 (9), 2083-2090, 1999 | 21 | 1999 |
Differentially cleaving peptides as a strategy for controlled drug release in human retinal pigment epithelial cells M Bhattacharya, S Sarkhel, J Peltoniemi, R Broadbridge, M Tuomainen, ... Journal of Controlled Release 251, 37-48, 2017 | 20 | 2017 |
Asymmetric usage of antagonist charged residues drives interleukin-5 receptor recruitment but is insufficient for receptor activation T Ishino, U Pillalamarri, D Panarello, M Bhattacharya, C Urbina, S Horvat, ... Biochemistry 45 (4), 1106-1115, 2006 | 20 | 2006 |
A dimeric layered structure of a 4-oxo-4, 5-dihydro-1H-pyrazolo [3, 4-d] pyrimidine compound K Avasthi, DS Rawat, S Sarkhel, PR Maulik Acta Crystallographica Section C: Crystal Structure Communications 58 (6 …, 2002 | 14 | 2002 |
High-throughput in vitro drug release and pharmacokinetic simulation as a tool for drug delivery system development: application to intravitreal ocular administration S Sarkhel, E Ramsay, LS Kontturi, J Peltoniemi, A Urtti International Journal of Pharmaceutics 477 (1-2), 469-475, 2014 | 10 | 2014 |