Electrophoretic mobility shift assay (EMSA) for detecting protein–nucleic acid interactions LM Hellman, MG Fried Nature protocols 2 (8), 1849-1861, 2007 | 1489 | 2007 |
Computational design of the affinity and specificity of a therapeutic T cell receptor BG Pierce, LM Hellman, M Hossain, NK Singh, CW Vander Kooi, Z Weng, ... PLoS computational biology 10 (2), e1003478, 2014 | 99 | 2014 |
T cell receptor cross-reactivity expanded by dramatic peptide–MHC adaptability TP Riley, LM Hellman, MH Gee, JL Mendoza, JA Alonso, KC Foley, ... Nature chemical biology 14 (10), 934-942, 2018 | 93 | 2018 |
Cutting edge: evidence for a dynamically driven T cell signaling mechanism WF Hawse, MM Champion, MV Joyce, LM Hellman, M Hossain, V Ryan, ... The Journal of Immunology 188 (12), 5819-5823, 2012 | 93 | 2012 |
Differential scanning fluorimetry based assessments of the thermal and kinetic stability of peptide–MHC complexes LM Hellman, L Yin, Y Wang, SJ Blevins, TP Riley, OS Belden, TT Spear, ... Journal of immunological methods 432, 95-101, 2016 | 77 | 2016 |
Furin processing of semaphorin 3F determines its anti-angiogenic activity by regulating direct binding and competition for neuropilin MW Parker, LM Hellman, P Xu, MG Fried, CW Vander Kooi Biochemistry 49 (19), 4068-4075, 2010 | 75 | 2010 |
Structural mechanism of laforin function in glycogen dephosphorylation and lafora disease M Raththagala, MK Brewer, MW Parker, AR Sherwood, BK Wong, S Hsu, ... Molecular cell 57 (2), 261-272, 2015 | 71 | 2015 |
How an alloreactive T-cell receptor achieves peptide and MHC specificity Y Wang, NK Singh, TT Spear, LM Hellman, KH Piepenbrink, ... Proceedings of the National Academy of Sciences 114 (24), E4792-E4801, 2017 | 60 | 2017 |
Improving T cell receptor on-target specificity via structure-guided design LM Hellman, KC Foley, NK Singh, JA Alonso, TP Riley, JR Devlin, ... Molecular Therapy 27 (2), 300-313, 2019 | 57 | 2019 |
Cell-wall remodeling by the zinc-protease AmpDh3 from Pseudomonas aeruginosa M Lee, C Artola-Recolons, C Carrasco-López, S Martínez-Caballero, ... Journal of the American chemical society 135 (34), 12604-12607, 2013 | 55 | 2013 |
Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells T Moore, CR Wagner, GM Scurti, KA Hutchens, C Godellas, AL Clark, ... Cancer Immunology, Immunotherapy 67, 311-325, 2018 | 52 | 2018 |
Reaction products and the X-ray structure of AmpDh2, a virulence determinant of Pseudomonas aeruginosa S Martínez-Caballero, M Lee, C Artola-Recolons, C Carrasco-López, ... Journal of the American chemical society 135 (28), 10318-10321, 2013 | 50 | 2013 |
Dynamically driven allostery in MHC proteins: Peptide-dependent tuning of class I MHC global flexibility CM Ayres, ET Abualrous, A Bailey, C Abraham, LM Hellman, SA Corcelli, ... Frontiers in immunology 10, 966, 2019 | 49 | 2019 |
FOXO3–NF-κB RelA protein complexes reduce proinflammatory cell signaling and function MG Thompson, M Larson, A Vidrine, K Barrios, F Navarro, K Meyers, ... The Journal of Immunology 195 (12), 5637-5647, 2015 | 47 | 2015 |
Hexahistidine-tag-specific optical probes for analyses of proteins and their interactions C Zhao, LM Hellman, X Zhan, WS Bowman, SW Whiteheart, MG Fried Analytical biochemistry 399 (2), 237-245, 2010 | 46 | 2010 |
Trimeric transmembrane domain interactions in paramyxovirus fusion proteins: roles in protein folding, stability, and function EC Smith, SE Smith, JR Carter, SR Webb, KM Gibson, LM Hellman, ... Journal of Biological Chemistry 288 (50), 35726-35735, 2013 | 45 | 2013 |
Role of Munc13-4 as a Ca2+-dependent tether during platelet secretion MC Chicka, Q Ren, D Richards, LM Hellman, J Zhang, MG Fried, ... Biochemical Journal 473 (5), 627-639, 2016 | 41 | 2016 |
Beyond anchoring: the expanding role of the hendra virus fusion protein transmembrane domain in protein folding, stability, and function EC Smith, MR Culler, LM Hellman, MG Fried, TP Creamer, RE Dutch Journal of virology 86 (6), 3003-3013, 2012 | 38 | 2012 |
Muropeptide Binding and the X-ray Structure of the Effector Domain of the Transcriptional Regulator AmpR of Pseudomonas aeruginosa DA Dik, T Domínguez-Gil, M Lee, D Hesek, B Byun, J Fishovitz, ... Journal of the american chemical society 139 (4), 1448-1451, 2017 | 37 | 2017 |
Residues in the hendra virus fusion protein transmembrane domain are critical for endocytic recycling A Popa, JR Carter, SE Smith, L Hellman, MG Fried, RE Dutch Journal of virology 86 (6), 3014-3026, 2012 | 37 | 2012 |