Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population ME Levine, JA Suarez, S Brandhorst, P Balasubramanian, CW Cheng, ... Cell metabolism 19 (3), 407-417, 2014 | 1072 | 2014 |
A periodic diet that mimics fasting promotes multi-system regeneration, enhanced cognitive performance, and healthspan S Brandhorst, IY Choi, M Wei, CW Cheng, S Sedrakyan, G Navarrete, ... Cell metabolism 22 (1), 86-99, 2015 | 896 | 2015 |
Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy C Lee, L Raffaghello, S Brandhorst, FM Safdie, G Bianchi, ... Science translational medicine 4 (124), 124ra27-124ra27, 2012 | 810 | 2012 |
Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease M Wei, S Brandhorst, M Shelehchi, H Mirzaei, CW Cheng, J Budniak, ... Science translational medicine 9 (377), eaai8700, 2017 | 555 | 2017 |
A diet mimicking fasting promotes regeneration and reduces autoimmunity and multiple sclerosis symptoms IY Choi, L Piccio, P Childress, B Bollman, A Ghosh, S Brandhorst, ... Cell reports 15 (10), 2136-2146, 2016 | 521 | 2016 |
Spermidine promotes stress resistance in Drosophila melanogaster through autophagy-dependent and-independent pathways N Minois, D Carmona-Gutierrez, MA Bauer, P Rockenfeller, T Eisenberg, ... Cell death & disease 3 (10), e401-e401, 2012 | 489 | 2012 |
Fasting-mimicking diet reduces HO-1 to promote T cell-mediated tumor cytotoxicity S Di Biase, C Lee, S Brandhorst, B Manes, R Buono, CW Cheng, ... Cancer cell 30 (1), 136-146, 2016 | 360 | 2016 |
Fasting enhances the response of glioma to chemo-and radiotherapy F Safdie, S Brandhorst, M Wei, W Wang, C Lee, S Hwang, PS Conti, ... Public Library of Science 7 (9), e44603, 2012 | 255 | 2012 |
Fasting-mimicking diet modulates microbiota and promotes intestinal regeneration to reduce inflammatory bowel disease pathology P Rangan, I Choi, M Wei, G Navarrete, E Guen, S Brandhorst, N Enyati, ... Cell reports 26 (10), 2704-2719. e6, 2019 | 251 | 2019 |
Fasting-mimicking diet and hormone therapy induce breast cancer regression I Caffa, V Spagnolo, C Vernieri, F Valdemarin, P Becherini, M Wei, ... Nature 583 (7817), 620-624, 2020 | 242 | 2020 |
Safety and feasibility of fasting in combination with platinum-based chemotherapy TB Dorff, S Groshen, A Garcia, M Shah, D Tsao-Wei, H Pham, CW Cheng, ... BMC cancer 16, 1-9, 2016 | 220 | 2016 |
Fasting and caloric restriction in cancer prevention and treatment S Brandhorst, VD Longo Metabolism in cancer, 241-266, 2016 | 182 | 2016 |
Dietary restrictions and nutrition in the prevention and treatment of cardiovascular disease S Brandhorst, VD Longo Circulation research 124 (6), 952-965, 2019 | 126 | 2019 |
Short-term calorie and protein restriction provide partial protection from chemotoxicity but do not delay glioma progression S Brandhorst, M Wei, S Hwang, TE Morgan, VD Longo Experimental gerontology 48 (10), 1120-1128, 2013 | 115 | 2013 |
Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers M Di Tano, F Raucci, C Vernieri, I Caffa, R Buono, M Fanti, S Brandhorst, ... Nature Communications 11 (1), 2332, 2020 | 107 | 2020 |
The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan K Yen, HH Mehta, SJ Kim, YH Lue, J Hoang, N Guerrero, J Port, Q Bi, ... Aging (Albany NY) 12 (12), 11185, 2020 | 84 | 2020 |
Humanin prevents age-related cognitive decline in mice and is associated with improved cognitive age in humans K Yen, J Wan, HH Mehta, B Miller, A Christensen, ME Levine, ... Scientific reports 8 (1), 14212, 2018 | 82 | 2018 |
Protein quantity and source, fasting-mimicking diets, and longevity S Brandhorst, VD Longo Advances in nutrition 10, S340-S350, 2019 | 79 | 2019 |
Protective effects of short-term dietary restriction in surgical stress and chemotherapy S Brandhorst, E Harputlugil, JR Mitchell, VD Longo Ageing research reviews 39, 68-77, 2017 | 74 | 2017 |
Time-restricted eating, intermittent fasting, and fasting-mimicking diets in weight loss M Fanti, A Mishra, VD Longo, S Brandhorst Current obesity reports 10, 70-80, 2021 | 68 | 2021 |