Effects of net charge and the number of positively charged residues on the biological activity of amphipathic α‐helical cationic antimicrobial peptides Z Jiang, AI Vasil, JD Hale, REW Hancock, ML Vasil, RS Hodges Peptide Science 90 (3), 369-383, 2008 | 540 | 2008 |
Rational Design of α‐Helical Antimicrobial Peptides to Target Gram‐negative Pathogens, Acinetobacter baumannii and Pseudomonas aeruginosa: Utilization of … Z Jiang, AI Vasil, L Gera, ML Vasil, RS Hodges Chemical biology & drug design 77 (4), 225-240, 2011 | 138 | 2011 |
Effects of hydrophobicity on the antifungal activity of α‐helical antimicrobial peptides Z Jiang, BJ Kullberg, H Van Der Lee, AI Vasil, JD Hale, CT Mant, ... Chemical biology & drug design 72 (6), 483-495, 2008 | 97 | 2008 |
Anti-tuberculosis activity of α-helical antimicrobial peptides: de novo designed L-and D-enantiomers versus L-and D-LL37 Z Jiang, M P. Higgins, J Whitehurst, K O. Kisich, M I. Voskuil, R S. Hodges Protein and peptide letters 18 (3), 241-252, 2011 | 75 | 2011 |
“Specificity determinants” improve therapeutic indices of two antimicrobial peptides piscidin 1 and dermaseptin S4 against the Gram-negative pathogens Acinetobacter baumannii … Z Jiang, AI Vasil, ML Vasil, RS Hodges Pharmaceuticals 7 (4), 366-391, 2014 | 72 | 2014 |
De Novo designed amphipathic α-helical antimicrobial peptides incorporating dab and dap residues on the polar face to treat the gram-negative pathogen, Acinetobacter baumannii CT Mant, Z Jiang, L Gera, T Davis, KL Nelson, S Bevers, RS Hodges Journal of medicinal chemistry 62 (7), 3354-3366, 2019 | 51 | 2019 |
Effects of net charge and the number of positively charged residues on the biological activity of amphipathic α-helical cationic antimicrobial peptides Z Jiang, AI Vasil, J Hale, REW Hancock, ML Vasil, RS Hodges the 20th American Peptide Symposium 2007, Montreal, Quebec, Canada, 561-562, 2009 | 46* | 2009 |
Role of positively charged residues on the polar and non‐polar faces of amphipathic α‐helical antimicrobial peptides on specificity and selectivity for Gram‐negative pathogens Z Jiang, CT Mant, M Vasil, RS Hodges Chemical biology & drug design 91 (1), 75-92, 2018 | 29 | 2018 |
An improved approach to hydrophilic interaction chromatography of peptides: Salt gradients in the presence of high isocratic acetonitrile concentrations CT Mant, Z Jiang, BE Boyes, RS Hodges Journal of Chromatography A 1277, 15-25, 2013 | 16 | 2013 |
Development of antimicrobial peptides as therapeutic agents RS Hodges, Z Jiang, J Whitehurst, CT Mant Development of Therapeutic Agents Handbook, 2011 | 15 | 2011 |
Dermaseptin-type and piscidin-type antimicrobial peptides Z Jiang, RS Hodges, L Gera US Patent 10,221,222, 2019 | 14* | 2019 |
Platform technology to generate broadly cross‐reactive antibodies to α‐helical epitopes in hemagglutinin proteins from influenza A viruses Z Jiang, L Gera, CT Mant, B Hirsch, Z Yan, JA Shortt, DD Pollock, Z Qian, ... Peptide Science 106 (2), 144-159, 2016 | 12 | 2016 |
Separation of highly charged (+ 5 to+ 10) amphipathic α-helical peptide standards by cation-exchange and reversed-phase high-performance liquid chromatography CT Mant, A Byars, S Ankarlo, Z Jiang, RS Hodges Journal of Chromatography A 1574, 60-70, 2018 | 5 | 2018 |
Design of new antimicrobial peptides (AMPs) with “specificity determinants” that encode selectivity for gram negative pathogens and remove both gram-positive activity and … Z Jiang, L Gera, CT Mant, RS Hodges Proceedings of the 24th American Peptide Symposium, 245-248, 2015 | 4 | 2015 |
Antimicrobial Peptides and Methods of Use RS Hodges, Z Jiang US Patent App. 12/574,545, 2010 | 4 | 2010 |
Effect of net positive charge and charge distribution on the polar face of amphipathic alpha-helical antimicrobial peptides on their biological and biophysical properties Z Jiang, AI Vasil, ML Vasil, RS Hodges the 21st American Peptide Symposium 2009, Bloomington, IN, USA 92 (4), 266-267, 2009 | 2* | 2009 |
Development of novel broad Spectrum anticancer small molecule Peptidomimetics with Nanomolar activity L Gera, J Tentler, SG Eckhardt, Z Jiang, A D'Alessandro, RS Hodges Twenty‐fourth American Peptide Symposium, Orlando, FL, 241-244, 2015 | 1 | 2015 |
Amphipathic alpha-helical antimicrobial peptides treat infections by gram-negative pathogens RS Hodges, Z Jiang, L Gera US Patent App. 17/423,611, 2022 | | 2022 |
Antimicrobial peptides and methods of treating gram-negative pathogens: polar and non-polar face analogs RS Hodges, Z Jiang, L Gera US Patent 10,874,745, 2020 | | 2020 |
Antimicrobial peptides and methods of treating gram-negative pathogen infections: polar and non-polar face analogs RS Hodges, Z Jiang, L Gera US Patent App. 16/616,372, 2020 | | 2020 |