From big data to precision medicine T Hulsen, SS Jamuar, AR Moody, JH Karnes, O Varga, S Hedensted, ... Frontiers in medicine 6, 34, 2019 | 455 | 2019 |
Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis CJ Rhodes, K Batai, M Bleda, M Haimel, L Southgate, M Germain, ... The Lancet Respiratory Medicine 7 (3), 227-238, 2019 | 171 | 2019 |
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C9 and HLA‐B Genotypes and Phenytoin Dosing: 2020 Update JH Karnes, AE Rettie, AA Somogyi, R Huddart, AE Fohner, CM Formea, ... Clinical Pharmacology & Therapeutics 109 (2), 302-309, 2021 | 158 | 2021 |
Biobanks and electronic medical records: enabling cost-effective research E Bowton, JR Field, S Wang, JS Schildcrout, SL Van Driest, JT Delaney, ... Science translational medicine 6 (234), 234cm3-234cm3, 2014 | 144 | 2014 |
Phenome-wide scanning identifies multiple diseases and disease severity phenotypes associated with HLA variants JH Karnes, L Bastarache, CM Shaffer, S Gaudieri, Y Xu, AM Glazer, ... Science Translational Medicine 9 (389), eaai8708, 2017 | 115 | 2017 |
Warfarin pharmacogenomics in diverse populations JB Kaye, LE Schultz, HE Steiner, RA Kittles, LH Cavallari, JH Karnes Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 37 (9 …, 2017 | 111 | 2017 |
Exome sequencing implicates an increased burden of rare potassium channel variants in the risk of drug-induced long QT interval syndrome P Weeke, JD Mosley, D Hanna, JT Delaney, C Shaffer, QS Wells, ... Journal of the American College of Cardiology 63 (14), 1430-1437, 2014 | 94 | 2014 |
Comparison of HLA allelic imputation programs JH Karnes, CM Shaffer, L Bastarache, S Gaudieri, AM Glazer, HE Steiner, ... PloS one 12 (2), e0172444, 2017 | 78 | 2017 |
A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough JD Mosley, CM Shaffer, SL Van Driest, PE Weeke, QS Wells, JH Karnes, ... The pharmacogenomics journal 16 (3), 231-237, 2016 | 68 | 2016 |
Genome-wide association and pathway analysis of left ventricular function after anthracycline exposure in adults QS Wells, OJ Veatch, JP Fessel, AY Joon, RT Levinson, JD Mosley, ... Pharmacogenetics and genomics 27 (7), 247-254, 2017 | 61 | 2017 |
A genome-wide association study of heparin-induced thrombocyto-penia using an electronic medical record JH Karnes, RM Cronin, J Rollin, A Teumer, C Pouplard, CM Shaffer, ... Thrombosis and haemostasis 113 (04), 772-781, 2015 | 60 | 2015 |
Genome-wide association study in African Americans with acute respiratory distress syndrome identifies the selectin P ligand gene as a risk factor C Bime, N Pouladi, S Sammani, K Batai, N Casanova, T Zhou, CL Kempf, ... American journal of respiratory and critical care medicine 197 (11), 1421-1432, 2018 | 59 | 2018 |
Antihypertensive medications: benefits of blood pressure lowering and hazards of metabolic effects JH Karnes, RM Cooper-DeHoff Expert review of cardiovascular therapy 7 (6), 689-702, 2009 | 59 | 2009 |
Applications of immunopharmacogenomics: predicting, preventing, and understanding immune-mediated adverse drug reactions JH Karnes, MA Miller, KD White, KC Konvinse, RK Pavlos, AJ Redwood, ... Annual review of pharmacology and toxicology 59 (1), 463-486, 2019 | 51 | 2019 |
Innovation in clinical pharmacy practice and opportunities for academic–practice partnership American College of Clinical Pharmacy, PO Gubbins, ST Micek, ... Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 34 (5 …, 2014 | 51 | 2014 |
Mendelian randomisation and experimental medicine approaches to interleukin-6 as a drug target in pulmonary arterial hypertension M Toshner, C Church, L Harbaum, C Rhodes, SSV Moreschi, J Liley, ... European Respiratory Journal 59 (3), 2022 | 49 | 2022 |
Immunopharmacogenomics: mechanisms of HLA‐associated drug reactions P Deshpande, RJ Hertzman, AM Palubinsky, JB Giles, JH Karnes, ... Clinical Pharmacology & Therapeutics 110 (3), 607-615, 2021 | 44 | 2021 |
Cost-effectiveness of anticoagulants for suspected heparin-induced thrombocytopenia in the United States A Aljabri, Y Huckleberry, JH Karnes, M Gharaibeh, HI Kutbi, Y Raz, S Yun, ... Blood, The Journal of the American Society of Hematology 128 (26), 3043-3051, 2016 | 40 | 2016 |
Clinical and genetic factors associated with cutaneous squamous cell carcinoma in kidney and heart transplant recipients ML Sanders, JH Karnes, JC Denny, DM Roden, TA Ikizler, KA Birdwell Transplantation direct 1 (4), 1-7, 2015 | 36 | 2015 |
Mining the plasma proteome for insights into the molecular pathology of pulmonary arterial hypertension L Harbaum, CJ Rhodes, J Wharton, A Lawrie, JH Karnes, AA Desai, ... American Journal of Respiratory and Critical Care Medicine 205 (12), 1449-1460, 2022 | 32 | 2022 |