Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer CM Phelan, KB Kuchenbaecker, JP Tyrer, SP Kar, K Lawrenson, ... Nature genetics 49 (5), 680-691, 2017 | 458 | 2017 |
A transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants A Gusev, K Lawrenson, X Lin, PC Lyra Jr, S Kar, KC Vavra, F Segato, ... Nature genetics 51 (5), 815-823, 2019 | 115 | 2019 |
The impact of lipid metabolism on breast cancer: a review about its role in tumorigenesis and immune escape D Zipinotti dos Santos, JC de Souza, TM Pimenta, B da Silva Martins, ... Cell Communication and Signaling 21 (1), 161, 2023 | 43 | 2023 |
Integration of functional assay data results provides strong evidence for classification of hundreds of BRCA1 variants of uncertain significance PCM Lyra Jr, TC Nepomuceno, MLM de Souza, GF Machado, MF Veloso, ... Genetics in Medicine 23 (2), 306-315, 2021 | 33 | 2021 |
Functional analysis and fine mapping of the 9p22. 2 ovarian cancer susceptibility locus MA Buckley, NT Woods, JP Tyrer, G Mendoza-Fandiño, K Lawrenson, ... Cancer research 79 (3), 467-481, 2019 | 27 | 2019 |
Conventional cancer treatment I dos Santos Guimarães, RD Daltoé, AL Herlinger, KP Madeira, ... Cancer treatment-conventional and innovative approaches, 2013 | 17 | 2013 |
Inhibition of CXCR2 plays a pivotal role in re-sensitizing ovarian cancer to cisplatin treatment TB Henriques, DZ Dos Santos, I dos Santos Guimarães, NG Tessarollo, ... Aging (albany NY) 13 (10), 13405, 2021 | 14 | 2021 |
Targeting the PI3K/AKT/mTOR pathway in cancer cells IS Guimarães, NG Tessarollo, P Lyra-Junior, DZ dos Santos, RC Zampier, ... Updates on cancer treatment, 2015 | 13 | 2015 |
Functional landscape of common variants associated with susceptibility to epithelial ovarian cancer PCM Lyra, LB Rangel, ANA Monteiro Current Epidemiology Reports 7, 49-57, 2020 | 9 | 2020 |
Two distinct mechanisms underlie estrogen-receptor-negative breast cancer susceptibility at the 2p23. 2 locus G Mendoza-Fandiño, PCM Lyra Jr, TC Nepomuceno, CM Harro, ... European Journal of Human Genetics 30 (4), 465-473, 2022 | 7 | 2022 |
Identification of two genetic loci associated with leukopenia after chemotherapy in patients with breast cancer PA Fasching, D Liu, S Scully, JN Ingle, PC Lyra Jr, B Rack, A Hein, ... Clinical Cancer Research 28 (15), 3342-3355, 2022 | 6 | 2022 |
EMBRACE Study, GEMO Study Collaborators, HEBON Study, KConFab Investigators, OPAL study group CM Phelan, KB Kuchenbaecker, JP Tyrer, SP Kar, K Lawrenson, ... Identification of 12, 0 | 6 | |
GWAS in breast cancer PCM Lyra‐Junior, NG Tessarollo, IS Guimarães, TB Henriques, ... Breast Cancer-From Biology to Medicine, 2017 | 5 | 2017 |
Functional analysis and clinical classification of 462 germline BRCA2 missense variants affecting the DNA binding domain C Hu, H Huang, J Na, C Lumby, M Abozaid, MA Holdren, TJ Rao, ... The American Journal of Human Genetics 111 (3), 584-593, 2024 | 4 | 2024 |
Saturation genome editing-based functional evaluation and clinical classification of BRCA2 single nucleotide variants H Huang, C Hu, J Na, SN Hart, RD Gnanaolivu, M Abozaid, T Rao, ... bioRxiv, 2023.12. 14.571597, 2023 | 2 | 2023 |
Target Cancer Therapy T Ladislau, KP Madeira, RD Daltoé, IS Guimarães, SF Teixeira, ... Cancer Treatment-Conventional and Innovative Approaches, 38-62, 2013 | 2 | 2013 |
Integration of functional data to classify BRCA1/2 missense variants: An ENIGMA project P Lyra, L Dalcolmo, M Parsons, T Nepomuceno, S Brito, NPN Nguyen, ... Cancer Research 84 (6_Supplement), 7325-7325, 2024 | 1 | 2024 |
Saturation genome editing-based functional evaluation and clinical classification of BRCA2 single nucleotide variants. F Couch, H Huang, T Pesaran, R Karam, S Yadav, SM Domchek, ... Journal of Clinical Oncology 42 (16_suppl), 10511-10511, 2024 | | 2024 |
Assessment of BRCA1 and BRCA2 Germline Variant Data From Patients With Breast Cancer in a Real-World Data Registry TC Nepomuceno, P Lyra, J Zhu, F Yi, RH Martin, D Lupu, L Peterson, ... JCO Clinical Cancer Informatics 8, e2300251, 2024 | | 2024 |
Abstract PR09: Functional and clinical characterization of hypomorphic missense variants in the BRCA2 cancer predisposition gene H Huang, C Hu, J Na, M Abozaid, A Munankarmy, T Rao, CAD Lumby, ... Cancer Research 84 (3_Supplement_1), PR09-PR09, 2024 | | 2024 |