关注
Paulo Cilas Morais Lyra Junior
Paulo Cilas Morais Lyra Junior
其他姓名Paulo Lyra, Paulo Lyra-Jr
H. Lee Moffitt Cancer Center
在 ufes.br 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer
CM Phelan, KB Kuchenbaecker, JP Tyrer, SP Kar, K Lawrenson, ...
Nature genetics 49 (5), 680-691, 2017
4582017
A transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants
A Gusev, K Lawrenson, X Lin, PC Lyra Jr, S Kar, KC Vavra, F Segato, ...
Nature genetics 51 (5), 815-823, 2019
1152019
The impact of lipid metabolism on breast cancer: a review about its role in tumorigenesis and immune escape
D Zipinotti dos Santos, JC de Souza, TM Pimenta, B da Silva Martins, ...
Cell Communication and Signaling 21 (1), 161, 2023
432023
Integration of functional assay data results provides strong evidence for classification of hundreds of BRCA1 variants of uncertain significance
PCM Lyra Jr, TC Nepomuceno, MLM de Souza, GF Machado, MF Veloso, ...
Genetics in Medicine 23 (2), 306-315, 2021
332021
Functional analysis and fine mapping of the 9p22. 2 ovarian cancer susceptibility locus
MA Buckley, NT Woods, JP Tyrer, G Mendoza-Fandiño, K Lawrenson, ...
Cancer research 79 (3), 467-481, 2019
272019
Conventional cancer treatment
I dos Santos Guimarães, RD Daltoé, AL Herlinger, KP Madeira, ...
Cancer treatment-conventional and innovative approaches, 2013
172013
Inhibition of CXCR2 plays a pivotal role in re-sensitizing ovarian cancer to cisplatin treatment
TB Henriques, DZ Dos Santos, I dos Santos Guimarães, NG Tessarollo, ...
Aging (albany NY) 13 (10), 13405, 2021
142021
Targeting the PI3K/AKT/mTOR pathway in cancer cells
IS Guimarães, NG Tessarollo, P Lyra-Junior, DZ dos Santos, RC Zampier, ...
Updates on cancer treatment, 2015
132015
Functional landscape of common variants associated with susceptibility to epithelial ovarian cancer
PCM Lyra, LB Rangel, ANA Monteiro
Current Epidemiology Reports 7, 49-57, 2020
92020
Two distinct mechanisms underlie estrogen-receptor-negative breast cancer susceptibility at the 2p23. 2 locus
G Mendoza-Fandiño, PCM Lyra Jr, TC Nepomuceno, CM Harro, ...
European Journal of Human Genetics 30 (4), 465-473, 2022
72022
Identification of two genetic loci associated with leukopenia after chemotherapy in patients with breast cancer
PA Fasching, D Liu, S Scully, JN Ingle, PC Lyra Jr, B Rack, A Hein, ...
Clinical Cancer Research 28 (15), 3342-3355, 2022
62022
EMBRACE Study, GEMO Study Collaborators, HEBON Study, KConFab Investigators, OPAL study group
CM Phelan, KB Kuchenbaecker, JP Tyrer, SP Kar, K Lawrenson, ...
Identification of 12, 0
6
GWAS in breast cancer
PCM Lyra‐Junior, NG Tessarollo, IS Guimarães, TB Henriques, ...
Breast Cancer-From Biology to Medicine, 2017
52017
Functional analysis and clinical classification of 462 germline BRCA2 missense variants affecting the DNA binding domain
C Hu, H Huang, J Na, C Lumby, M Abozaid, MA Holdren, TJ Rao, ...
The American Journal of Human Genetics 111 (3), 584-593, 2024
42024
Saturation genome editing-based functional evaluation and clinical classification of BRCA2 single nucleotide variants
H Huang, C Hu, J Na, SN Hart, RD Gnanaolivu, M Abozaid, T Rao, ...
bioRxiv, 2023.12. 14.571597, 2023
22023
Target Cancer Therapy
T Ladislau, KP Madeira, RD Daltoé, IS Guimarães, SF Teixeira, ...
Cancer Treatment-Conventional and Innovative Approaches, 38-62, 2013
22013
Integration of functional data to classify BRCA1/2 missense variants: An ENIGMA project
P Lyra, L Dalcolmo, M Parsons, T Nepomuceno, S Brito, NPN Nguyen, ...
Cancer Research 84 (6_Supplement), 7325-7325, 2024
12024
Saturation genome editing-based functional evaluation and clinical classification of BRCA2 single nucleotide variants.
F Couch, H Huang, T Pesaran, R Karam, S Yadav, SM Domchek, ...
Journal of Clinical Oncology 42 (16_suppl), 10511-10511, 2024
2024
Assessment of BRCA1 and BRCA2 Germline Variant Data From Patients With Breast Cancer in a Real-World Data Registry
TC Nepomuceno, P Lyra, J Zhu, F Yi, RH Martin, D Lupu, L Peterson, ...
JCO Clinical Cancer Informatics 8, e2300251, 2024
2024
Abstract PR09: Functional and clinical characterization of hypomorphic missense variants in the BRCA2 cancer predisposition gene
H Huang, C Hu, J Na, M Abozaid, A Munankarmy, T Rao, CAD Lumby, ...
Cancer Research 84 (3_Supplement_1), PR09-PR09, 2024
2024
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