Human aquaporins: regulators of transcellular water flow RE Day, P Kitchen, DS Owen, C Bland, L Marshall, AC Conner, RM Bill, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1840 (5), 1492-1506, 2014 | 371 | 2014 |
Targeting aquaporin-4 subcellular localization to treat central nervous system edema P Kitchen, MM Salman, AM Halsey, C Clarke-Bland, JA MacDonald, ... Cell 181 (4), 784-799. e19, 2020 | 355 | 2020 |
Lifting the lid on GPCRs: the role of extracellular loops M Wheatley, D Wootten, MT Conner, J Simms, R Kendrick, RT Logan, ... British journal of pharmacology 165 (6), 1688-1703, 2012 | 349 | 2012 |
Beyond water homeostasis: Diverse functional roles of mammalian aquaporins P Kitchen, RE Day, MM Salman, MT Conner, RM Bill, AC Conner Biochimica et Biophysica Acta (BBA)-General Subjects 1850 (12), 2410-2421, 2015 | 152 | 2015 |
High-throughput screening platforms in the discovery of novel drugs for neurodegenerative diseases H Aldewachi, RN Al-Zidan, MT Conner, MM Salman Bioengineering 8 (2), 30, 2021 | 140 | 2021 |
Inhibitors of mammalian aquaporin water channels M Abir-Awan, P Kitchen, MM Salman, MT Conner, AC Conner, RM Bill International journal of molecular sciences 20 (7), 1589, 2019 | 123 | 2019 |
Rapid aquaporin translocation regulates cellular water flow MT Conner, AC Conner, CE Bland, LHJ Taylor, JEP Brown, HR Parri, ... Journal of Biological Chemistry 287 (14), 11516-11525, 2012 | 108 | 2012 |
Identification and molecular mechanisms of the rapid tonicity-induced relocalization of the aquaporin 4 channel P Kitchen, RE Day, LHJ Taylor, MM Salman, RM Bill, MT Conner, ... Journal of Biological Chemistry 290 (27), 16873-16881, 2015 | 105 | 2015 |
Hypothermia increases aquaporin 4 (AQP 4) plasma membrane abundance in human primary cortical astrocytes via a calcium/transient receptor potential vanilloid 4 (TRPV 4)‐and … MM Salman, P Kitchen, MN Woodroofe, JE Brown, RM Bill, AC Conner, ... European Journal of Neuroscience 46 (9), 2542-2547, 2017 | 93 | 2017 |
Systematic analysis of the entire second extracellular loop of the V1a vasopressin receptor: key residues, conserved throughout a G-protein-coupled receptor family, identified M Conner, SR Hawtin, J Simms, D Wootten, Z Lawson, AC Conner, ... Journal of Biological Chemistry 282 (24), 17405-17412, 2007 | 89 | 2007 |
Membrane trafficking of aquaporin 1 is mediated by protein kinase C via microtubules and regulated by tonicity MT Conner, AC Conner, JEP Brown, RM Bill Biochemistry 49 (5), 821-823, 2010 | 68 | 2010 |
Plasma membrane abundance of human aquaporin 5 is dynamically regulated by multiple pathways P Kitchen, F Öberg, J Sjöhamn, K Hedfalk, RM Bill, AC Conner, ... PloS one 10 (11), e0143027, 2015 | 65 | 2015 |
Transcriptome analysis suggests a role for the differential expression of cerebral aquaporins and the MAPK signalling pathway in human temporal lobe epilepsy MM Salman, MA Sheilabi, D Bhattacharyya, P Kitchen, AC Conner, ... European Journal of Neuroscience 46 (5), 2121-2132, 2017 | 64 | 2017 |
Improving recombinant eukaryotic membrane protein yields in Pichia pastoris: The importance of codon optimization and clone selection F Öberg, J Sjöhamn, MT Conner, RM Bill, K Hedfalk Molecular membrane biology 28 (6), 398-411, 2011 | 63 | 2011 |
Transcriptome analysis of gene expression provides new insights into the effect of mild therapeutic hypothermia on primary human cortical astrocytes cultured under hypoxia MM Salman, P Kitchen, MN Woodroofe, RM Bill, AC Conner, PR Heath, ... Frontiers in Cellular Neuroscience 11, 386, 2017 | 60 | 2017 |
Functional and biophysical analysis of the C-terminus of the CGRP-receptor; a family B GPCR M Conner, MR Hicks, T Dafforn, TJ Knowles, C Ludwig, S Staddon, ... Biochemistry 47 (32), 8434-8444, 2008 | 58 | 2008 |
Charged extracellular residues, conserved throughout a G-protein-coupled receptor family, are required for ligand binding, receptor activation, and cell-surface expression SR Hawtin, J Simms, M Conner, Z Lawson, RA Parslow, J Trim, ... Journal of Biological Chemistry 281 (50), 38478-38488, 2006 | 57 | 2006 |
An emerging consensus on aquaporin translocation as a regulatory mechanism AC Conner, RM Bill, MT Conner Molecular membrane biology 30 (1), 101-112, 2013 | 55 | 2013 |
Molecular mechanisms governing aquaporin relocalisation A Markou, L Unger, M Abir-Awan, A Saadallah, A Halsey, Z Balklava, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1864 (4), 183853, 2022 | 54 | 2022 |
Water channel pore size determines exclusion properties but not solute selectivity P Kitchen, MM Salman, SU Pickel, J Jennings, S Törnroth-Horsefield, ... Scientific Reports 9 (1), 20369, 2019 | 51 | 2019 |