| Immunogenicity of a DNA vaccine candidate for COVID-19 TRF Smith, A Patel, S Ramos, D Elwood, X Zhu, J Yan, EN Gary, ... Nature communications 11 (1), 2601, 2020 | 705 | 2020 |
| Intradermal-delivered DNA vaccine induces durable immunity mediating a reduction in viral load in a rhesus macaque SARS-CoV-2 challenge model A Patel, JN Walters, EL Reuschel, K Schultheis, E Parzych, EN Gary, ... Cell Reports Medicine 2 (10), 2021 | 83* | 2021 |
| SARS-CoV-2 assays to detect functional antibody responses that block ACE2 recognition in vaccinated animals and infected patients SN Walker, N Chokkalingam, EL Reuschel, M Purwar, Z Xu, EN Gary, ... Journal of Clinical Microbiology 58 (11), 10.1128/jcm. 01533-20, 2020 | 61 | 2020 |
| In vivo delivery of synthetic DNA–encoded antibodies induces broad HIV-1–neutralizing activity MC Wise, Z Xu, E Tello-Ruiz, C Beck, A Trautz, A Patel, STC Elliott, ... The Journal of clinical investigation 130 (2), 827-837, 2020 | 40 | 2020 |
| In vivo assembly of nanoparticles achieved through synergy of structure‐based protein engineering and synthetic DNA generates enhanced adaptive immunity Z Xu, MC Wise, N Chokkalingam, S Walker, E Tello‐Ruiz, STC Elliott, ... Advanced Science 7 (8), 1902802, 2020 | 38 | 2020 |
| A DNA-Launched Nanoparticle Vaccine Elicits CD8+ T-cell Immunity to Promote In Vivo Tumor Control Z Xu, N Chokkalingam, E Tello-Ruiz, MC Wise, MA Bah, S Walker, ... Cancer immunology research 8 (11), 1354-1364, 2020 | 22 | 2020 |
| Nucleic acid delivery of immune-focused SARS-CoV-2 nanoparticles drives rapid and potent immunogenicity capable of single-dose protection KM Konrath, K Liaw, Y Wu, X Zhu, SN Walker, Z Xu, K Schultheis, ... Cell reports 38 (5), 2022 | 20 | 2022 |
| DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2 EM Parzych, J Du, AR Ali, K Schultheis, D Frase, TRF Smith, J Cui, ... Nature Communications 13 (1), 5886, 2022 | 17 | 2022 |
| Incorporation of a novel CD4+ helper epitope identified from Aquifex aeolicus enhances humoral responses induced by DNA and protein vaccinations Z Xu, N Chokkalingam, E Tello-Ruiz, S Walker, DW Kulp, DB Weiner Iscience 23 (8), 2020 | 11 | 2020 |
| Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer Z Xu, S Walker, MC Wise, N Chokkalingam, M Purwar, A Moore, ... Nature Communications 13 (1), 695, 2022 | 4* | 2022 |
| Engineered antibody cytokine chimera synergizes with DNA-launched nanoparticle vaccines to potentiate melanoma suppression in vivo NJ Tursi, Z Xu, M Helble, S Walker, K Liaw, N Chokkalingam, T Kannan, ... Frontiers in immunology 14, 1072810, 2023 | 1 | 2023 |
| In vivo delivery of engineered synthetic DNA-encoded SARS-CoV-2 monoclonal antibodies for pre-exposure prophylaxis in non-human primates A Patel, K Rosenke, EM Parzych, F Feldmann, S Bharti, AJ Griffin, ... Emerging Microbes & Infections 13 (1), 2294860, 2024 | | 2024 |
| DNA Delivery of Immune-Focused Nanoparticle Vaccines Drives Rapid, Potent, and Broad Immunogenicity Against Sars-Cov-2 and Its Variants K Liaw, K Konrath, Y Wu, X Xu, S Walker, Z Xu, N Chokkalingam, N Tursi, ... 2022 AIChE Annual Meeting, 2022 | | 2022 |
| DNA-launched nanoparticle vaccines induce cytolytic T cell responses for in vivo tumor control K Liaw, Z Xu, N Chokkalingam, D Kulp, D Weiner Cancer Research 82 (12_Supplement), 1738-1738, 2022 | | 2022 |
| DNA Delivery of Immune-Focused SARS-CoV-2 Nanoparticle Vaccines Drives Rapid and Potent Immunogenicity and Achieves Single-Dose Protection K Liaw, K Konrath, Y Wu, Z Xu, S Walker, K Schultheis, N Chokkalingam, ... MOLECULAR THERAPY 30 (4), 508-509, 2022 | | 2022 |
| DNA-launched HPV E7 nanoparticle vaccine induces potent anti-tumor cytolytic T-cell responses K Liaw, Z Xu, N Tursi, N Chokkalingam, D Kulp, D Weiner Cancer Research 81 (13 Supplement), 268-268, 2021 | | 2021 |
| Engineered Antibody Cytokine Chimera Synergizes with DNA-Launched Nanoparticle Vaccines to Potentiate Suppression of Melanoma Proliferation In Vivo NJ Tursi, Z Xu, S Walker, K Liaw, N Chokkalingam, M Helble, Y Wu, ... MOLECULAR THERAPY 29 (4), 301-302, 2021 | | 2021 |
| Development of a generalizable DNA-launched nanoparticle platform to enhance adaptive immunity of DNA vaccines Z Xu, M Wise, N Chokkalingam, S Walker, D Kulp, D Weiner EUROPEAN JOURNAL OF IMMUNOLOGY 49, 1664-1665, 2019 | | 2019 |
| Abstract LB-294: Cellular microRNAs whose expression is altered by the oncogenic mouse polyomavirus N Chokkalingam, CK Sung Cancer Research 75 (15_Supplement), LB-294-LB-294, 2015 | | 2015 |
