Dynamic adipocyte phosphoproteome reveals that Akt directly regulates mTORC2 SJ Humphrey, G Yang, P Yang, DJ Fazakerley, J Stöckli, JY Yang, ... Cell metabolism 17 (6), 1009-1020, 2013 | 416 | 2013 |
Global phosphoproteomic analysis of human skeletal muscle reveals a network of exercise-regulated kinases and AMPK substrates NJ Hoffman, BL Parker, R Chaudhuri, KH Fisher-Wellman, M Kleinert, ... Cell metabolism 22 (5), 922-935, 2015 | 365 | 2015 |
GLUT4 exocytosis J Stöckli, DJ Fazakerley, DE James Journal of cell science 124 (24), 4147-4159, 2011 | 316 | 2011 |
Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration S Balaban, RF Shearer, LS Lee, M van Geldermalsen, M Schreuder, ... Cancer & metabolism 5 (1), 1-14, 2017 | 313 | 2017 |
Mapping insulin/GLUT4 circuitry AF Rowland, DJ Fazakerley, DE James Traffic 12 (6), 672-681, 2011 | 200 | 2011 |
Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation DJ Fazakerley, AY Minard, JR Krycer, KC Thomas, J Stöckli, DJ Harney, ... Journal of Biological Chemistry 293 (19), 7315-7328, 2018 | 111 | 2018 |
Selective insulin resistance in adipocytes SX Tan, KH Fisher-Wellman, DJ Fazakerley, Y Ng, H Pant, J Li, CC Meoli, ... Journal of Biological Chemistry 290 (18), 11337-11348, 2015 | 111 | 2015 |
Muscle and adipose tissue insulin resistance: malady without mechanism? DJ Fazakerley, JR Krycer, AL Kearney, SL Hocking, DE James Journal of Lipid Research 60 (10), 1720-1732, 2019 | 109 | 2019 |
Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle EP Taddeo, RC Laker, DS Breen, YN Akhtar, BM Kenwood, JA Liao, ... Molecular metabolism 3 (2), 124-134, 2014 | 107 | 2014 |
Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance DJ Fazakerley, R Chaudhuri, P Yang, GJ Maghzal, KC Thomas, JR Krycer, ... Elife 7, e32111, 2018 | 102 | 2018 |
Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity LE Wu, D Samocha-Bonet, PT Whitworth, DJ Fazakerley, N Turner, ... Molecular metabolism 3 (4), 465-473, 2014 | 102 | 2014 |
mTORC1 is a major regulatory node in the FGF21 signaling network in adipocytes AY Minard, SX Tan, P Yang, DJ Fazakerley, W Domanova, BL Parker, ... Cell reports 17 (1), 29-36, 2016 | 98 | 2016 |
Lipid and glucose metabolism in hepatocyte cell lines and primary mouse hepatocytes: a comprehensive resource for in vitro studies of hepatic metabolism SR Nagarajan, M Paul-Heng, JR Krycer, DJ Fazakerley, AF Sharland, ... American Journal of Physiology-Endocrinology and Metabolism 316 (4), E578-E589, 2019 | 92 | 2019 |
Kinetic evidence for unique regulation of GLUT4 trafficking by insulin and AMP-activated protein kinase activators in L6 myotubes DJ Fazakerley, GD Holman, A Marley, DE James, J Stöckli, ACF Coster Journal of Biological Chemistry 285 (3), 1653-1660, 2010 | 85 | 2010 |
Amplification and demultiplexing in insulin-regulated Akt protein kinase pathway in adipocytes SX Tan, Y Ng, CC Meoli, A Kumar, PS Khoo, DJ Fazakerley, JR Junutula, ... Journal of Biological Chemistry 287 (9), 6128-6138, 2012 | 79 | 2012 |
Terminal galactosylation and sialylation switching on membrane glycoproteins upon TNF-alpha-induced insulin resistance in adipocytes BL Parker, M Thaysen-Andersen, DJ Fazakerley, M Holliday, NH Packer, ... Molecular & Cellular Proteomics 15 (1), 141-153, 2016 | 78 | 2016 |
Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo M Kleinert, L Sylow, DJ Fazakerley, JR Krycer, KC Thomas, AJ Oxbøll, ... Molecular metabolism 3 (6), 630-641, 2014 | 74 | 2014 |
Global redox proteome and phosphoproteome analysis reveals redox switch in Akt Z Su, JG Burchfield, P Yang, SJ Humphrey, G Yang, D Francis, S Yasmin, ... Nature communications 10 (1), 5486, 2019 | 73 | 2019 |
High dietary fat and sucrose result in an extensive and time-dependent deterioration in health of multiple physiological systems in mice JG Burchfield, MA Kebede, CC Meoli, J Stöckli, PT Whitworth, AL Wright, ... Journal of biological chemistry 293 (15), 5731-5745, 2018 | 72 | 2018 |
The RabGAP TBC1D1 plays a central role in exercise-regulated glucose metabolism in skeletal muscle J Stöckli, CC Meoli, NJ Hoffman, DJ Fazakerley, H Pant, ME Cleasby, ... Diabetes 64 (6), 1914-1922, 2015 | 70 | 2015 |